Search Results - "Roukounakis, Aristomenis"
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Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim
Published in Cell death and differentiation (01-02-2020)“…The BH3-only class of Bcl-2 family proteins triggers mitochondrial apoptosis. Several mechanisms are used to restrain the pro-apoptotic activity of these…”
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Journal Article -
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Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis
Published in Genes & development (01-09-2017)“…The Bcl-2 family protein Bim triggers mitochondrial apoptosis. Bim is expressed in nonapoptotic cells at the mitochondrial outer membrane, where it is…”
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Journal Article