Search Results - "Rouillard, Nicholas"

Spatial and temporal variation in New Hampshire bat diets by O’Rourke, Devon, Rouillard, Nicholas P., Parise, Katy L., Foster, Jeffrey T.

“…Insectivorous bats consume a diverse array of arthropod prey, with diets varying by bat species, sampling location, and season. North American bat diets remain…”
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Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations by Dillon, Marcus M., Rouillard, Nicholas P., Van Dam, Brian, Gallet, Romain, Cooper, Vaughn S.

“…Beneficial mutations fuel adaptation by altering phenotypes that enhance the fit of organisms to their environment. However, the phenotypic effects of…”
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1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in the TRAC locus outperforms lentiviral-based engineering of T cells by Narayan, Santosh, Drain, Allison P, Swanson, Nathaniel, Rouillard, Nicholas, Warner, Tyler, Danek, Nicole, Gareau, Ken, Black, Cheryl, Parsons, James, Thomas, Anthony, Liang, Jinsheng, Shen, Luhua, Tetrault, Tanya, Nguyen, Vince, Priyata, Iqraa, Vidyasagar, Sarah, Francis, Joshua, He, Xingyue, Browne, Patrick J, Lamothe, Rebecca C, Storlie, Meghan D, Cost, Gregory J, Schmitt, Thomas M, Greenberg, Philip D, Chandran, Smita S, Klebanoff, Christopher A, Gupta, Ankit, Hallet, Damien, Shapiro, Gary, Nguyen, Kim, Vincent, Loic

“…BackgroundThe AFNT-212 cell therapy consists of autologous CD8+ and CD4+ T cells expressing 1) a T Cell Receptor (TCR) specific for the prevalent oncogenic…”
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355 Directing a high avidity KRAS G12D-specific TCR engineered with a CD8αβ co-receptor and chimeric cytokine receptor using non-viral knock-in enhances anti-tumor responses by Drain, Allison P, Rouillard, Nicholas, Swanson, Nathaniel, Narayan, Santosh, Warner, Tyler, Danek, Nicole, Gareau, Ken, Black, Cheryl, Parsons, James, Thomas, Anthony, Liang, Jinsheng, Shen, Luhua, Tetrault, Tanya, Nguyen, Vince, Priyata, Iqraa, Vidyasagar, Sarah, Francis, Joshua, He, Xingyue, Browne, Patrick J, Lamothe, Rebecca C, Storlie, Meghan D, Cost, Gregory J, Schmitt, Thomas M, Greenberg, Philip D, Chandran, Smita S, Klebanoff, Christopher A, Gupta, Ankit, Hallet, Damien, Shapiro, Gary, Nguyen, Kim, Vincent, Loic

“…BackgroundAdoptive T cell therapy has demonstrated clinical activity in a subset of patients with solid tumors; however, consistent responses will require…”
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Differences in liver and mortality outcomes of non-alcoholic fatty liver disease by race and ethnicity: A longitudinal real-world study by Nguyen, Vy H., Le, Isaac, Ha, Audrey, Le, Richard Hieu, Rouillard, Nicholas Ajit, Fong, Ashley, Gudapati, Surya, Park, Jung Eun, Maeda, Mayumi, Barnett, Scott, Cheung, Ramsey, Nguyen, Mindie H.

“…Background/Aims: Understanding of nonalcoholic fatty liver disease (NAFLD) continues to expand, but the relationship between race and ethnicity and NAFLD…”
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Su1555 ASSOCIATION BETWEEN REDUCED LIVER AND NON-LIVER MORTALITY AND BARIATRIC SURGERY IN PATIENTS WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE (MASLD)-RELATED LIVER CIRRHOSIS – IMPACT OF SURGICAL APPROACH, 2005-2019 by Rouillard, Nicholas, Kam, Leslie Y., Barnett, Scott, Zhang, Xinrong, Manikat, Richie, Cheung, Ramsey, Nguyen, Mindie H.

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Sa1552 ETHNIC DIFFERENCES IN LIVER AND MORTALITY OUTCOMES OF NONALCOHOLIC FATTY LIVER DISEASE: A REAL-WORLD STUDY WITH LONGITUDINAL FOLLOW-UP by Nguyen, Vy H., Le, Isaac, Ha, Audrey, Le, Richard H., Rouillard, Nicholas, Fong, Ashley, Gudapati, Surya T., Park, Jung Eun, Maeda, Mayumi, Barnett, Scott, Henry, Linda, Cheung, Ramsey, Nguyen, Mindie H.

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Sa1578 NATURAL HISTORY OF NON-ALCOHOLIC FATTY LIVER DISEASE AMONG REAL-WORLD PATIENTS by Nguyen, Vy H., Ha, Audrey, Rouillard, Nicholas, Le, Richard H., Fong, Ashley, Gudapati, Surya T., Park, Jung Eun, Maeda, Mayumi, Barnett, Scott, Henry, Linda, Cheung, Ramsey, Nguyen, Mindie H.

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Bariatric Surgery Reduced Long-Term Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Cirrhosis by Rouillard, Nicholas A., Barnett, Scott D., Zhang, Xinrong, Kam, Leslie, Manikat, Richie, Cheung, Ramsey, Nguyen, Mindie H.

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Bariatric Surgery Reduces Long-Term Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Cirrhosis by Rouillard, Nicholas A, Barnett, Scott D, Zhang, Xinrong, Kam, Leslie, Manikat, Richie, Cheung, Ramsey, Nguyen, Mindie H

“…With the obesity pandemic, metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common liver disease and a leading cause of end-stage…”
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Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations: DIVERSE RESPONSES TO SELECTION OF E. coli POPULATIONS by Dillon, Marcus M., Rouillard, Nicholas P., Van Dam, Brian, Gallet, Romain, Cooper, Vaughn S.

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Differential Mortality Outcomes in Real-world Patients with Lean, Nonobese, and Obese Nonalcoholic Fatty Liver Disease by Nguyen, Vy H, Ha, Audrey, Rouillard, Nicholas Ajit, Le, Richard Hieu, Fong, Ashley, Gudapati, Surya, Park, Jung Eun, Maeda, Mayumi, Barnett, Scott, Cheung, Ramsey, Nguyen, Mindie H

“…Nonalcoholic fatty liver disease (NAFLD) is commonly associated with obesity but can develop in normal-weight people (lean NAFLD). We compared outcomes in…”
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Su1396: DIFFERENTIAL CLINICAL PRESENTATIONS AND OUTCOMES AMONG U.S. PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) BY RACE AND ETHNICITY: A LONGITUDINAL STUDY by Rouillard, Nicholas, Nguyen, Vy, Le, Richard H., Gudapati, Surya T., Tran, Sally, Cheung, Ramsey, Nguyen, Mindie H.

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Abstract 10: Non-viral engineered T cell therapy specific for the hotspot mutation p53 R175H that integrates signal 1 (TCR), signal 2 (co-stimulation) and signal 3 (cytokine) and co-opts FasL-dependent apoptosis to achieve a coordinated antitumor CD4/8 T cell response by Narayan, Santosh, Gareau, Ken, Gupta, Ankit, Ferrell, Josh, Rouillard, Nicholas, Warner, Tyler, Liang, Jinsheng, Shen, Luhua, Tetrault, Tanya, Francis, Joshua, He, Xingyue, Browne, Patrick J., Lamothe, Rebecca, Storlie, Meghan D., Cost, Gregory J., Schmitt, Thomas M., Greenberg, Philip D., Chandran, Smita S., Hallet, Damien, Gormally, Michael, Klebanoff, Chistopher A., Shapiro, Gary, Nguyen, Kim, Vincent, Loïc

“…Adoptive T cell therapy (ACT) has demonstrated antitumor efficacy in patients with solid cancers but requires further optimization to become a reproducibly…”
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Abstract 9: AFNT-212: A TRAC -knocked-in KRASG12D-specific TCR-T cell product enhanced with CD8αβ and a chimeric cytokine receptor for treatment of solid cancers by Drain, Allison, Rouillard, Nicholas, Swanson, Nathaniel, Canestraro, Martina, Narayan, Santosh, Warner, Tyler, Danek, Nicole, Gareau, Ken, Liang, Jinsheng, Shen, Luhua, Tetrault, Tanya, Priyata, Iqraa, Vidyasagar, Sarah, Riggins-Walker, Taylor, Liu, Hui-Wen, Pechhold, Klaus, Brown, Lauren, Francis, Joshua, He, Xingyue, Browne, Patrick, Lamothe, Rebecca, Storlie, Meghan, Cost, Gregory, Schmitt, Thomas M., Greenberg, Philip D., Chandran, Smita S., Klebanoff, Christopher A., Lam, Hubert, Gupta, Ankit, Hallet, Damien, Shapiro, Gary, Nguyen, Kim, Vincent, Loïc

“…The KRASG12D mutation is an ideal target for anti-cancer therapies as its expression is typically clonal, restricted to cancer tissue, and is among the most…”
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