Search Results - "Rouhana, Sarah"
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Ranolazine: An Old Drug with Emerging Potential; Lessons from Pre-Clinical and Clinical Investigations for Possible Repositioning
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2022)“…Ischemic heart disease is a significant public health problem with high mortality and morbidity. Extensive scientific investigations from basic sciences to…”
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Perimenopause Decreases SERCA2a Activity in the Hearts of a Mouse Model of Ovarian Failure
Published in Biomolecules (Basel, Switzerland) (01-06-2024)“…Risk of cardiovascular disease mortality rises in women after menopause. While increased cardiovascular risk is largely attributed to postmenopausal declines…”
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Abstract P3119: Identifying The Windows Of Cardiac Risk And Opportunity In Menopause
Published in Circulation research (04-08-2023)“…Abstract only Post-acute myocardial infarction (AMI) mortality has significant sex differences with a bias towards higher rates in women. While treatment…”
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Accelerated Ovarian Failure (AOF) is an Effective Transitional Menopausal Model for the Study of Alzheimer’s Disease
Published in Alzheimer's & dementia (01-12-2023)“…Background Biological females account for 70% of Alzheimer’s disease (AD) cases. It’s hypothesized that the estrogen depletion females experience during…”
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Sex differences in the cardiac stress response following SARS-CoV-2 infection of ferrets
Published in American journal of physiology. Heart and circulatory physiology (01-11-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection damages the heart, increasing the risk of adverse cardiovascular events. Female sex…”
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Early calcium handling imbalance in pressure overload-induced heart failure with nearly normal left ventricular ejection fraction
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2019)“…Heart failure with preserved ejection fraction (HFpEF) is a common clinical syndrome associated with high morbidity and mortality. Therapeutic options are…”
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