Search Results - "Rougon, G."

Fibronectin expression in glioblastomas promotes cell cohesion, collective invasion of basement membrane in vitro and orthotopic tumor growth in mice by Serres, E, Debarbieux, F, Stanchi, F, Maggiorella, L, Grall, D, Turchi, L, Burel-Vandenbos, F, Figarella-Branger, D, Virolle, T, Rougon, G, Van Obberghen-Schilling, E

“…Glioblastoma multiforme (GBM) are highly invasive and angiogenic malignancies with a median survival time from diagnosis of <15 months. Previous work has…”
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New insights into the diversity and function of neuronal immunoglobulin superfamily molecules by ROUGON, Geneviève, HOBERT, Oliver

“…Immunoglobulin superfamily (IgSF) proteins are implicated in diverse steps of brain development, including neuronal migration, axon pathfinding, target…”
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Cis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A by Castellani, V., De Angelis, E., Kenwrick, S., Rougon, G.

“…Mutations in the L1 gene induce a spectrum of human neurological disorders due to abnormal development of several brain structures and fiber tracts. Among its…”
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Dual Functional Activity of Semaphorin 3B Is Required for Positioning the Anterior Commissure by Julien, Falk, Bechara, Ahmad, Fiore, Roberto, Nawabi, Homaira, Zhou, Heather, Hoyo-Becerra, Carolina, Bozon, Muriel, Rougon, Geneviève, Grumet, Martin, Püschel, Andreas W., Sanes, Joshua R., Castellani, Valérie

“…Chemorepulsion by semaphorins plays a critical role during the development of neuronal projections. Although semaphorin-induced chemoattraction has been…”
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Negative Regulation of Central Nervous System Myelination by Polysialylated-Neural Cell Adhesion Molecule by Charles, P., Hernandez, M. P., Stankoff, B., Aigrot, M. S., Colin, C., Rougon, G., Zalc, B., Lubetzki, C.

“…Many factors have been shown to promote myelination, but few have been shown to be inhibitory. Here, we show that polysialylated-neural cell adhesion molecule…”
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Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance by Castellani, V, Chédotal, A, Schachner, M, Faivre-Sarrailh, C, Rougon, G

“…In humans, defects of the corticospinal tract have been attributed to mutations in the gene encoding L1 CAM, a phenotype that is reproduced in L1-deficient…”
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Capsiate administration results in an uncoupling protein-3 downregulation, an enhanced muscle oxidative capacity and a decreased abdominal fat content in vivo by Faraut, B, Giannesini, B, Matarazzo, V, Le Fur, Y, Rougon, G, Cozzone, P.J, Bendahan, D

“…Objectives: The involvement of skeletal muscle mitochondrial uncoupling protein-3 (UCP3) in the control of energy expenditure in skeletal muscle and at the…”
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Brain-Derived Neurotrophic Factor Restores Long-Term Potentiation in Polysialic Acid-Neural Cell Adhesion Molecule-Deficient Hippocampus by Muller, D., Djebbara-Hannas, Z., Jourdain, P., Vutskits, L., Durbec, P., Rougon, G., Kiss, J. Z.

“…The neural cell adhesion molecule (NCAM) and its polysialylated form (PSA-NCAM) contribute to long-term potentiation (LTP) in the CA1 hippocampus. Here we…”
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PSA-NCAM modulates BDNF-dependent survival and differentiation of cortical neurons by Vutskits, L., Djebbara-Hannas, Z., Zhang, H., Paccaud, J.-P., Durbec, P., Rougon, G., Muller, D., Kiss, J. Z.

“…We show that the loss or inactivation of the polysialic acid (PSA) tail of neural cell adhesion molecule (NCAM) on rat cortical neurons in culture leads to…”
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PSA–NCAM Is Required for Activity-Induced Synaptic Plasticity by Muller, D, Wang, C, Skibo, G, Toni, N, Cremer, H, Calaora, V, Rougon, G, Kiss, J.Z

“…Hippocampal organotypic slice cultures maintained 10–20 days in vitro express a high level of the polysialylated embryonic form of neural cell adhesion…”
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Structure, metabolism and cell biology of polysialic acids by Rougon, G

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Increased Neurogenesis in Adult mCD24-Deficient Mice by Belvindrah, Richard, Rougon, Genevieve, Chazal, Genevieve

“…mCD24, a glycosylphosphatidylinositol-anchored highly glycosylated molecule, is expressed on differentiating neurons during development. In the adult CNS, its…”
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Mice deficient for the close homologue of the neural adhesion cell L1 (CHL1) display alterations in emotional reactivity and motor coordination by Pratte, M., Rougon, G., Schachner, M., Jamon, M.

“…Motor and cognitive phenotypes were assessed in mice deficient for the close homologue of the L1 adhesion molecule (CHL1). The CHL1-deficient mice displayed…”
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Downregulation of uncoupling protein-3 in vivo is linked to changes in muscle mitochondrial energy metabolism as a result of capsiate administration by Faraut, B, Giannesini, B, Matarazzo, V, Marqueste, T, Dalmasso, C, Rougon, G, Cozzone, P J, Bendahan, D

“…Although it has been suggested that the skeletal muscle mitochondrial uncoupling protein-3 (UCP3) is involved in regulating energy expenditure, its role is…”
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Pregnenolone sulfate enhances neurogenesis and PSA-NCAM in young and aged hippocampus by Mayo, W., Lemaire, V., Malaterre, J., Rodriguez, J.J., Cayre, M., Stewart, M.G., Kharouby, M., Rougon, G., Le Moal, M., Piazza, P.V., Abrous, D.N.

“…Age-dependent cognitive impairments have been correlated with functional and structural modifications in the hippocampal formation. In particular, the brain…”
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A novel role for polyamines in adult neurogenesis in rodent brain by Malaterre, Jordane, Strambi, Colette, Aouane, Aïcha, Strambi, Alain, Rougon, Geneviève, Cayre, Myriam

“…Although neurogenesis in the adult is known to be regulated by various internal cues such as hormones, growth factors and cell‐adherence molecules, downstream…”
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A semaphorin code defines subpopulations of spinal motor neurons during mouse development by Cohen, Samia, Funkelstein, Lydiane, Livet, Jean, Rougon, Geneviève, Henderson, Christopher E., Castellani, Valerie, Mann, Fanny

“…In the spinal cord, motor neurons (MNs) with similar muscle targets and sensory inputs are grouped together into motor pools. To date, relatively little is…”
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Selection of poly-alpha 2,8-sialic acid mimotopes from a random phage peptide library and analysis of their bioactivity by Torregrossa, Pascal, Buhl, Lone, Bancila, Mircea, Durbec, Pascale, Schafer, Claus, Schachner, Melitta, Rougon, Geneviève

“…Poly-alpha 2-8 sialic acid (PSA), attached to the neural cell adhesion molecule, is a permissive determinant for numerous morphogenetic and neural plasticity…”
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Modulating Sema3A signal with a L1 mimetic peptide is not sufficient to promote motor recovery and axon regeneration after spinal cord injury by Mire, Erik, Thomasset, Nicole, Jakeman, Lyn B., Rougon, Geneviève

“…We examined whether Sema3A, which is upregulated at the site of spinal cord injury, exerts a direct effect on axons. We used ASNKL peptide that prevents…”
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PSA‐NCAM: an important regulator of hippocampal plasticity by Cremer, H., Chazal, G., Lledo, P.M., Rougon, G., Montaron, M.F., Mayo, W., Le Moal, M., Abrous, D.N.

“…The Neural Cell Adhesion Molecule (NCAM) serves as a temporally and spatially regulated modulator of a variety of cell‐cell interactions. This review…”
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