Search Results - "Roughton, Grace A."

Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models by Gutierrez, Wade R., Scherer, Amanda, McGivney, Gavin R., Brockman, Qierra R., Knepper-Adrian, Vickie, Laverty, Emily A., Roughton, Grace A., Dodd, Rebecca D.

“…Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered…”
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Loss of Nf1 and Ink4a/Arf Are Associated with Sex-Dependent Growth Differences in a Mouse Model of Embryonal Rhabdomyosarcoma by Gutierrez, Wade R, Rytlewski, Jeffrey D, Scherer, Amanda, Roughton, Grace A, Carnevale, Nina C, Vyas, Krisha Y, McGivney, Gavin R, Brockman, Qierra R, Knepper-Adrian, Vickie, Dodd, Rebecca D

“…Rhabdomyosarcoma (RMS) is an aggressive form of cancer that accounts for half of all pediatric soft tissue sarcomas. Little progress has been made in improving…”
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Augmenting chemotherapy with low-dose decitabine through an immune-independent mechanism by Gutierrez, Wade R, Scherer, Amanda, Rytlewski, Jeffrey D, Laverty, Emily A, Sheehan, Alexa P, McGivney, Gavin R, Brockman, Qierra R, Knepper-Adrian, Vickie, Roughton, Grace A, Quelle, Dawn E, Gordon, David J, Monga, Varun, Dodd, Rebecca D

“…The DNA methyltransferase inhibitor decitabine has classically been used to reactivate silenced genes and as a pretreatment for anticancer therapies. In a…”
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