Search Results - "Roug, Anne S."

Revisiting CLEC12A as leukaemic stem cell marker in AML: highlighting the necessity of precision diagnostics in patients eligible for targeted therapy by Bill, Marie, Aggerholm, Anni, Kjeldsen, Eigil, Roug, Anne S., Hokland, Peter, Nederby, Line

“…Summary Targeted therapy directed against rare disease‐propagating leukaemic stem cells (LSCs) is a promising prospect for improving the outcome of acute…”
Get full text

Soluble CD163 as a prognostic biomarker in B-cell chronic lymphocytic leukemia by Nederby, Line, Roug, Anne S., Knudsen, Signe S., Skovbo, Anni, Kjeldsen, Eigil, Moller, Holger J., Hokland, Marianne

Get full text

Immunophenotypically defined stem cell subsets in paediatric AML are highly heterogeneous and demonstrate differences in BCL‐2 expression by cytogenetic subgroups by Petersen, Marianne A., Rosenberg, Carina A., Brøndum, Rasmus F., Aggerholm, Anni, Kjeldsen, Eigil, Rahbek, Ole, Ludvigsen, Maja, Hasle, Henrik, Roug, Anne S., Bill, Marie

“…In adult acute myeloid leukaemia (AML), immunophenotypic differences enable discrimination of leukaemic stem cells (LSCs) from healthy haematopoietic stem…”
Get full text

hMICL and CD123 in combination with a CD45/CD34/CD117 backbone – a universal marker combination for the detection of minimal residual disease in acute myeloid leukaemia by Roug, Anne S., Larsen, Hanne Ø., Nederby, Line, Just, Tom, Brown, Gordon, Nyvold, Charlotte G., Ommen, Hans B., Hokland, Peter

“…Summary Real‐time quantitative polymerase chain reaction (qPCR) has been extensively validated for the detection of minimal residual disease (MRD) in acute…”
Get full text

The prognostic effect of smoking status on intensively treated acute myeloid leukaemia – A Danish nationwide cohort study by Kristensen, Daniel, Nielsen, Lars B., Roug, Anne S., Kristensen, Tove‐Christina C., El‐Galaly, Tarec C., Nørgaard, Jan M., Marcher, Claus W., Schöllkopf, Claudia, Theilgaard‐Mönch, Kim, Severinsen, Marianne T.

“…Summary With rising life expectancy, the importance of patient‐related prognostic factors and how to integrate such data into clinical decision‐making becomes…”
Get full text

Diagnosing and following adult patients with acute myeloid leukaemia in the genomic age by Roug, Anne S., Hansen, Marcus C., Nederby, Line, Hokland, Peter

“…Summary The diagnosis and follow‐up process of adult patients with acute myeloid leukaemia (AML) is challenging to clinicians and laboratory staff alike. While…”
Get full text

Nature and nurture: a case of transcending haematological pre‐malignancies in a pair of monozygotic twins adding possible clues on the pathogenesis of B‐cell proliferations by Hansen, Marcus C., Nyvold, Charlotte G., Roug, Anne S., Kjeldsen, Eigil, Villesen, Palle, Nederby, Line, Hokland, Peter

“…Summary We describe a comprehensive molecular analysis of a pair of monozygotic twins, who came to our attention when one experienced amaurosis fugax and was…”
Get full text

Direct costs of antineoplastic and supportive treatment for progressive multiple myeloma in a tax-based health system by Brøndum, Rasmus F, Vestergaard, Anne S, Børty, Lars, Vesteghem, Charles, Rytter, Anne S, Nielsen, Marlene M, Severinsen, Marianne T, Jensen, Paw, Gregersen, Henrik, El-Galaly, Tarec C, Dybkær, Karen, Ehlers, Lars H, Bøgsted, Martin, Roug, Anne S

“…To estimate current real-world costs of drugs and supportive care for the treatment of multiple myeloma in a tax-based health system. Forty-one patients were…”
Get full text

Combination of RNA- and exome sequencing: Increasing specificity for identification of somatic point mutations and indels in acute leukaemia by Hansen, Marcus C, Herborg, Laura L, Hansen, Maria, Roug, Anne S, Hokland, Peter

“…Graphical abstract…”
Get full text

Development of a Precision Medicine Workflow in Hematological Cancers, Aalborg University Hospital, Denmark by Bødker, Julie S, Sønderkær, Mads, Vesteghem, Charles, Schmitz, Alexander, Brøndum, Rasmus F, Sommer, Mia, Rytter, Anne S, Nielsen, Marlene M, Madsen, Jakob, Jensen, Paw, Pedersen, Inge S, Grubach, Lykke, Severinsen, Marianne T, Roug, Anne S, El-Galaly, Tarec C, Dybkær, Karen, Bøgsted, Martin

“…Within recent years, many precision cancer medicine initiatives have been developed. Most of these have focused on solid cancers, while the potential of…”
Get full text

Expression of the hMICL in acute myeloid leukemia—a highly reliable disease marker at diagnosis and during follow‐up by Larsen, Hanne Ø., Roug, Anne S., Just, Tom, Brown, Gordon D., Hokland, Peter

“…Background: Stable flow cytometric markers for malignant myeloid cells are highly warranted. Based on data from stem cell research, we hypothesized that the…”
Get full text

Interleukin-21 and rituximab enhance NK cell functionality in patients with B-cell chronic lymphocytic leukaemia by Eskelund, Christian W, Nederby, Line, Thysen, Anna H, Skovbo, Anni, Roug, Anne S, Hokland, Marianne E

“…Abstract We have examined natural killer (NK) cell functionality of 54 B-CLL patients upon in vitro stimulation with interleukin-21 (IL-21), together with the…”
Get full text

Cell sorting enables interphase fluorescence in situ hybridization detection of low BCR‐ABL1 producing stem cells in chronic myeloid leukaemia patients beyond deep molecular remission by Kooten Niekerk, Peter B., Petersen, Charlotte C., Nyvold, Charlotte G., Ommen, Hans B., Roug, Anne S., Nederby, Line, Hokland, Peter, Kjeldsen, Eigil

“…Summary The exact disease state of chronic myeloid leukaemia (CML) patients in deep molecular remission is unknown, because even the most sensitive…”
Get full text

The CD94/NKG2C-expressing NK cell subset is augmented in chronic lymphocytic leukemia patients with positive human cytomegalovirus serostatus by Petersen, Line, Roug, Anne S, Skovbo, Anni, Thysen, Anna H, Eskelund, Christian W, Hokland, Marianne E

“…Human cytomegalovirus (HCMV) manipulates the host immune system in various ways. Allegedly, HCMV infection is associated with increased percentages of a…”
Get more information

Increased expression of CD69 on T cells as an early immune marker for human cytomegalovirus reactivation in chronic lymphocytic leukemia patients by Petersen, Charlotte C, Nederby, Line, Roug, Anne S, Skovbo, Anni, Peterslund, Niels A, Hokland, Peter, Nielsen, Bendt, Hokland, Marianne

“…Reactivation of human cytomegalovirus (HCMV) remains a serious problem in immunosuppressed individuals. To investigate whether a change in the immune status…”
Get more information

Revisiting CLEC 12A as leukaemic stem cell marker in AML : highlighting the necessity of precision diagnostics in patients eligible for targeted therapy by Bill, Marie, Aggerholm, Anni, Kjeldsen, Eigil, Roug, Anne S., Hokland, Peter, Nederby, Line

“…Targeted therapy directed against rare disease‐propagating leukaemic stem cells ( LSC s) is a promising prospect for improving the outcome of acute myeloid…”
Get full text

Abstract 3648: Resolving copy number variations from existing exome SNP data without the need for sophisticated software by Hansen, Marcus C., Herborg, Laura L., Roug, Anne S., Chotirat, Sadudee, Auewarakul, Chirayu U., Kjeldsen, Eigil, Hokland, Peter

“…Several tools exists to evaluate copy-number variation (CNV) from sequencing read data. Here, the aim is to investigate whether larger CNVs in leukemia can be…”
Get full text

h MICL and CD 123 in combination with a CD 45/ CD 34/ CD 117 backbone – a universal marker combination for the detection of minimal residual disease in acute myeloid leukaemia by Roug, Anne S., Larsen, Hanne Ø., Nederby, Line, Just, Tom, Brown, Gordon, Nyvold, Charlotte G., Ommen, Hans B., Hokland, Peter

“…Real‐time quantitative polymerase chain reaction (q PCR ) has been extensively validated for the detection of minimal residual disease ( MRD ) in acute myeloid…”
Get full text

Cell sorting enables interphase fluorescence in situ hybridization detection of low BCR‐ABL 1 producing stem cells in chronic myeloid leukaemia patients beyond deep molecular remission by van Kooten Niekerk, Peter B., Petersen, Charlotte C., Nyvold, Charlotte G., Ommen, Hans B., Roug, Anne S., Nederby, Line, Hokland, Peter, Kjeldsen, Eigil

“…The exact disease state of chronic myeloid leukaemia ( CML ) patients in deep molecular remission is unknown, because even the most sensitive quantitative…”
Get full text