Search Results - "Roubos, Eric W."
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Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat
Published in PloS one (23-11-2011)“…Although the higher prevalence of depression in women than in men is well known, the neuronal basis of this sex difference is largely elusive. Male and female…”
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2
Leptin and the hypothalamo-pituitary–adrenal stress axis
Published in General and comparative endocrinology (15-05-2012)“…Highlights ► We review the functioning of leptin at the organ, cell and molecule level. ► Adipose leptin acts at 3 levels of the hypothalamo-pituitary–adrenal…”
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3
Restraint stress alters the secretory activity of neurons co-expressing urocortin-1, cocaine- and amphetamine-regulated transcript peptide and nesfatin-1 in the mouse Edinger–Westphal nucleus
Published in Brain research (04-03-2010)“…Abstract Central stress regulatory pathways utilize various neuropeptides, such as urocortin-1 (Ucn1) and cocaine- and amphetamine-regulated transcript peptide…”
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4
The gray area between synapse structure and function-Gray's synapse types I and II revisited
Published in Synapse (New York, N.Y.) (01-11-2011)“…On the basis of ultrastructural parameters, the concept was formulated that asymmetric Type I and symmetric Type II synapses are excitatory and inhibitory,…”
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TRH acts as a multifunctional hypophysiotropic factor in vertebrates
Published in General and comparative endocrinology (01-10-2009)“…Abstract Thyrotropin-releasing hormone (TRH) is the first hypothalamic hypophysiotropic neuropeptide whose sequence has been chemically characterized. The…”
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Effects of chronic administration of amitriptyline, gabapentin and minocycline on spinal brain-derived neurotrophic factor expression and neuropathic pain behavior in a rat chronic constriction injury model
Published in Regional anesthesia and pain medicine (01-03-2013)“…In animal models of neuropathic pain (NP), promising results have been reported with the administration of minocycline, possibly through inhibition of spinal…”
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Integration of stress and leptin signaling by CART producing neurons in the rodent midbrain centrally projecting Edinger-Westphal nucleus
Published in Frontiers in neuroanatomy (03-03-2014)“…Leptin targets the brain to regulate feeding, neuroendocrine function and metabolism. The leptin receptor is present in hypothalamic centers controlling energy…”
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Pituitary Adenylate Cyclase-Activating Polypeptide Regulates Brain-Derived Neurotrophic Factor Exon IV Expression through the VPAC1 Receptor in the Amphibian Melanotrope Cell
Published in Endocrinology (Philadelphia) (01-08-2008)“…In mammals, pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors PAC1-R, VPAC1-R, and VPAC2-R play a role in various physiological…”
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Chronic ether stress-induced response of urocortin 1 neurons in the Edinger–Westphal nucleus in the mouse
Published in Brain research (07-06-2005)“…Urocortin 1 (Ucn1) neurons, most abundantly expressed in the Edinger–Westphal nucleus (E-WN), respond to various acute challenges. In a recent study, we found…”
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Differential Neuroendocrine Expression of Multiple Brain-Derived Neurotrophic Factor Transcripts
Published in Endocrinology (Philadelphia) (01-03-2009)“…Brain-derived neurotrophic factor (BDNF) is a neurotrophin with important growth-promoting properties. We report here the first characterization of a BDNF gene…”
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11
Effects of maternal separation on dynamics of urocortin 1 and brain‐derived neurotrophic factor in the rat non‐preganglionic Edinger‐Westphal nucleus
Published in International journal of developmental neuroscience (01-08-2009)“…Although mood disorders are frequently genetically determined and to some degree gender‐dependent, the concept of early life ‘programming’, implying a relation…”
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12
Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain
Published in Brain research (09-02-2006)“…Corticotropin-releasing factor (CRF) acts through CRF 1 and CRF 2 receptors (CRF1, CRF2). To test the hypothesis that CRF controls the expression of these…”
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13
Sex differences in urocortin 1 dynamics in the non-preganglionic Edinger–Westphal nucleus of the rat
Published in Neuroscience research (2010)“…Women have higher vulnerability to stress and stress-induced diseases than men. Estrogen may be involved in the control of sex-dependent stress adaptation via…”
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Brain distribution and evidence for both central and neurohormonal actions of cocaine- and amphetamine-regulated transcript peptide in Xenopus laevis
Published in Journal of comparative neurology (1911) (01-04-2008)“…We tested the hypothesis that, in the amphibian Xenopus laevis, cocaine‐ and amphetamine‐regulated transcript peptide (CARTp) not only has widespread actions…”
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Analysis of the melanotrope cell neuroendocrine interface in two amphibian species, Rana ridibunda and Xenopus laevis : A celebration of 35 years of collaborative research
Published in General and comparative endocrinology (01-01-2011)“…Research highlights ► Overview of molecular and cellular mechanisms of neuroendocrine integration in the R. ridibunda and X. laevis melanotrope cell…”
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Overexpression of corticotropin-releasing hormone in transgenic mice and chronic stress-like autonomic and physiological alterations
Published in The European journal of neuroscience (01-11-2002)“…To gain a greater insight into the relationship between hyperactivity of the corticotropin‐releasing hormone (CRH) system and autonomic and physiological…”
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Sex-specific differences in the dynamics of cocaine- and amphetamine-regulated transcript and nesfatin-1 expressions in the midbrain of depressed suicide victims vs. controls
Published in Neuropharmacology (01-01-2012)“…An intriguing novel pathophysiological insight into mood disorders is the notion that one’s metabolic status influences mood. In rodents, cocaine- and…”
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Plasticity in the melanotrope neuroendocrine interface of Xenopus laevis
Published in Neuroendocrinology (01-01-2007)“…Melanotrope cells of the amphibian pituitary pars intermedia produce alpha-melanophore-stimulating hormone (alpha-MSH), a peptide which causes skin darkening…”
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Sex-dependent and differential responses to acute restraint stress of corticotropin-releasing factor-producing neurons in the rat paraventricular nucleus, central amygdala, and bed nucleus of the stria terminalis
Published in Journal of neuroscience research (01-01-2012)“…Male and female rodents respond differently to acute stress. We tested our hypothesis that this sex difference is based on differences in stress sensitivity of…”
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From frog integument to human skin: dermatological perspectives from frog skin biology
Published in Biological reviews of the Cambridge Philosophical Society (01-08-2014)“…ABSTRACT For over a century, frogs have been studied across various scientific fields, including physiology, embryology, neuroscience, (neuro)endocrinology,…”
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