Search Results - "Roubini, E"

Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding by Amit, Ido, Yakir, Liat, Katz, Menachem, Zwang, Yaara, Marmor, Mina D, Citri, Ami, Shtiegman, Keren, Alroy, Iris, Tuvia, Shmuel, Reiss, Yuval, Roubini, Eli, Cohen, Maya, Wides, Ron, Bacharach, Eran, Schubert, Ullrich, Yarden, Yosef

“…The tumor suppressor gene 101 (tsg101) regulates vesicular trafficking processes in yeast and mammals. We report a novel protein, Tal (Tsg101-associated…”
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Detection of ERK activation by a novel monoclonal antibody by Yung, Yuval, Dolginov, Yakov, Zhong, Yao, Rubinfeld, Hadara, Michael, Dan, Hanoch, Tamar, Roubini, Eli, Lando, Zeev, Zharhary, Dorit, Seger, Rony

“…The mitogen-activated protein kinase, ERK is activated by a dual phosphorylation on threonine and tyrosine residues. Using a synthetic diphospho peptide, we…”
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Cyclic parathyroid hormone-related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization by Chorev, Michael, Roubini, Eliahu, McKee, Roberta L, Gibbons, Susan W, Goldman, Mark E, Caulfield, Michael P, Rosenblatt, Michael

“…Cyclization of parathyroid hormone related protein (7-34)amide [PTHrP(7-34)NH2] via covalent bond formation between the epsilon-amino of Lys13 and the…”
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The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region by Caulfield, M P, McKee, R L, Goldman, M E, Duong, L T, Fisher, J E, Gay, C T, DeHaven, P A, Levy, J J, Roubini, E, Nutt, R F

“…Previous studies examining the interaction of PTH and PTH-related protein (PTHrP) with target tissue have for the most part emphasized the similarity between…”
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Toward nonpeptidal substance P mimetic analogues: design, synthesis, and biological activity by Chorev, M, Roubini, E, Gilon, C, Selinger, Z

“…1,4-Piperazine and 4-hydroxyproline, two small cyclic polyfunctional systems with defined stereochemistry, were introduced as "molecular scaffolds." We define…”
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Modifications of position 12 in a parathyroid hormone and parathyroid hormone-related protein: toward the design of highly potent antagonists by Chorev, Michael, Goldman, Mark E, McKee, Roberta L, Roubini, Eliahu, Levy, Jay J, Gay, C. Thomas, Reagan, Jane E, Fisher, John E, Caporale, Lynn H

“…Truncated N-terminal fragments of parathyroid hormone (PTH), [Tyr34]bovine PTH(7-34)NH2, and parathyroid hormone related protein (PTHrP), PTHrP(7-34)NH2,…”
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Pseudopeptide analogues of substance P and leucine enkephalinamide containing the psi (CH sub(2)O) modification: Synthesis and biological activity by Roubini, E, Laufer, R, Gilon, C, Selinger, Z, Roques, B P, Chorev, M

“…The isosteric methyleneoxy zeta (CH sub(2)O) function was employed as a novel peptide-bond surrogate and incorporated into sequences of two neuropeptides,…”
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Pseudopeptide analogs of substance P and leucine enkephalinamide containing the .psi.(methyleneoxy) modification: synthesis and biological activity by Roubini, Eli, Laufer, Ralph, Gilon, Chaim, Selinger, Zvi, Roques, Bernard P, Chorev, Michael

“…The isosteric methyleneoxy psi (CH2O) function was employed as a novel peptide-bond surrogate and incorporated into sequences of two neuropeptides, substance P…”
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Synthesis of fully active biotinylated analogs of parathyroid hormone and parathyroid hormone-related protein as tools for the characterization of parathyroid hormone receptors by Roubini, Eliahu, Duong, Le T, Gibbons, Susan W, Leu, Chih T, Caulfield, Michael P, Chorev, Michael, Rosenblatt, Michael

“…The synthesis, purification, and characterization of biotinylated analogues of parathyroid hormone (PTH) and PTH-related protein (PTHrP) are described. A novel…”
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Synthesis of fully active biotinylated analogues of parathyroid hormone and parathyroid hormone-related proteins as tools for the characterization of parathyroid hormone receptors by Roubini, E, Duong, L T, Gibbons, S W, Leu, C T, Caulfield, M P, Chorev, M, Rosenblatt, M

“…The synthesis, purification, and characterization of biotinylated analogues of parathyroid hormone (PTH) and PTH-related protein (PTHrP) are described. A novel…”
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Biological activity of parathyroid hormone antagonists substituted at position 13 by Chorev, M, Roubini, E, McKee, R L, Gibbons, S W, Reagan, J E, Goldman, M E, Caulfield, M P, Rosenblatt, M

“…Lysine occupies position 13 in the parathyroid hormone (PTH) antagonist, [Nle8,18,Tyr34]bPTH(7-34)NH2. Acylation of the epsilon-amino group in lysine 13 by a…”
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A novel, mild, specific and indirect maleimido-based radioiodolabeling method. Radiolabeling of analogs derived from parathyroid hormone (PTH) and PTH-related protein (PTHrP) by Chorev, M, Caulfield, M P, Roubini, E, McKee, R L, Gibbons, S W, Leu, C T, Levy, J J, Rosenblatt, M

“…In an effort to design a mild, non-oxidative and site-specific means of radiolabeling bioactive molecules we have employed maleimido-sulfhydryl chemistry to…”
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Effects of hydrophobic substitutions at position 18 on the potency of parathyroid hormone antagonists by Chorev, M, Roubini, E, Goldman, M E, McKee, R L, Gibbons, S W, Reagan, J E, Caulfield, M P, Rosenblatt, M

“…Position 18 in a parathyroid hormone (PTH) antagonist, [Nle8,18,Tyr34]bPTH(7-34)NH2 (ii), was shown to tolerate substitutions by a range of amino acids with…”
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Partially modified retro-inverso enkephalin analogues containing Gly3ψ(NH-CO)PHE4 modification, configurational lability by CHOREV, M, GILON, N, ROUBINI, E, ACKERMAN, E, LEVIAN-TEITELBAUM, D, ROSIN, M

“…Two partially modified retro-inverso analogues of Leu-enkephalin in which the peptide bond between Gly 3 -Phe 4 was reversed resulted from the incorporation of…”
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