Search Results - "Rotwein, P."

Local insulin-like growth factor I expression is essential for Purkinje neuron survival at birth by Croci, L, Barili, V, Chia, D, Massimino, L, van Vugt, R, Masserdotti, G, Longhi, R, Rotwein, P, Consalez, G G

“…IGF1, an anabolic and neuroprotective factor, promotes neuronal survival by blocking apoptosis. It is released into the bloodstream by the liver, or…”
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Myostatin and insulin-like growth factors in uremic sarcopenia: the yin and yang in muscle mass regulation by Mak, R.H., Rotwein, P.

“…Myostatin and the insulin-like growth factors (IGF-I and -II) play inhibitory and stimulatory roles, respectively, in the development and regulation of…”
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Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors by Stewart, C E, Rotwein, P

“…The insulin-like growth factors (IGFs), IGF-I and IGF-II, comprise a conserved pair of secreted proteins with diverse effects on growth, development, and…”
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Insulin-Like Growth Factor-Mediated Muscle Cell Survival: Central Roles for Akt and Cyclin-Dependent Kinase Inhibitor p21 by Lawlor, Margaret A., Rotwein, Peter

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression by Delling, Ulrike, Tureckova, Jolana, Lim, Hae W., De Windt, Leon J., Rotwein, Peter, Molkentin, Jeffery D.

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PL08 Deconstructing muscle differentiation: defining insulin-like growth factor actions in muscle development and repair by Rotwein, P, Anguiano, M, Gardner, S, Gross, S

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OR5,30 Distinct epigenetic actions of growth hormone and Stat5b by Chia, D.J, Rotwein, P

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Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality by Lau, M M, Stewart, C E, Liu, Z, Bhatt, H, Rotwein, P, Stewart, C L

“…Murine embryos that inherit a nonfunctional insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor (Igf2r) gene from their fathers are…”
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Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91 by GRONOWSKI, A. M, ROTWEIN, P

“…Growth hormone (GH) plays a central role in regulating growth and intermediary metabolism in vertebrates, although the mechanisms by which GH initiates these…”
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"Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II by FLORINI, J. R, MAGRI, K. A, EWTON, D. Z, JAMES, P. L, GRINDSTAFF, K, ROTWEIN, P. S

“…Differentiation of muscle cells to form postmitotic myotubes is usually viewed as being negatively controlled by medium components, sometimes designated…”
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Human growth disorders: molecular genetics of the growth hormone-insulin-like growth factor I axis by Rotwein, P

“…Rotwein P. Human growth disorders: molecular genetics of the growth hormone‐insulin‐like growth factor I axis. Acta Paidiatr 1999; Suppl 428: 148–51…”
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Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene by Shimatsu, A, Rotwein, P

“…Insulin-like growth factor I (IGF-I) plays a major role in mammalian growth and regenerative processes as a mediator of many of the biological effects of…”
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Two Insulin-Like Growth Factor I Messenger RNAs are Expressed in Human Liver by Rotwein, Peter

“…Through use of a synthetic oligonucleotide probe, human insulin-like growth factor I (IGF-I) cDNA clones were isolated from a liver library. Two types of cDNAs…”
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Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements by KAJIMOTO, Y, ROTWEIN, P

“…Insulin-like growth factor I plays a major role in cellular growth by mediating many of the actions of growth hormone. In mammals, IGF-I gene expression is…”
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Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth by DeVol, D L, Rotwein, P, Sadow, J L, Novakofski, J, Bechtel, P J

“…We have investigated the hypothesis that there is local regulation of insulin-like growth factor (IGF) gene expression during skeletal muscle growth…”
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Characterization of the Human Growth Hormone Receptor Gene and Demonstration of a Partial Gene Deletion in Two Patients with Laron-Type Dwarfism by Godowski, Paul J., Leung, David W., Meacham, Lillian R., Galgani, John P., Hellmiss, Renate, Keret, Ruth, Rotwein, Peter S., Parks, John S., Laron, Zvi, Wood, William I.

“…Laron-type dwarfism is an autosomal recessive genetic disorder that is characterized by high levels of growth hormone and low levels of insulin-like growth…”
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Insulin-like Growth Factor Binding Protein-5 Modulates Muscle Differentiation through an Insulin-like Growth Factor-Dependent Mechanism by James, Payton L., Claire E. H. Stewart, Rotwein, Peter

“…The insulin-like growth factor binding proteins (IGFBPs) are a family of six secreted proteins which bind to and modulate the actions of insulin-like growth…”
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CCAAT/enhancer-binding protein delta activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone by Umayahara, Y., Ji, C., Centrella, M., Rotwein, P., McCarthy, T. L.

“…Insulin-like growth factor-I (IGF-I) plays a key role in skeletal growth by stimulating bone cell replication and differentiation. We previously showed that…”
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Differential Expression of Insulin-Like Growth Factor Genes in Rat Central Nervous System by Rotwein, Peter, Burgess, Susan K., Milbrandt, Jeffrey D., James. E. Krause

“…A sensitive solution-hybridization assay was used to investigate the expression of genes encoding insulin-like growth factors I and II (IGF-I and -II) in the…”
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Rapid activation of insulin-like growth factor binding protein-5 gene transcription during myoblast differentiation by Rotwein, P, James, P L, Kou, K

“…Insulin-like growth factor binding proteins (IGFBPs) comprise a family of secreted proteins that bind insulin-like growth factors-I and -II (IGF-I and -II)…”
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