Search Results - "Rotwein, P"
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Local insulin-like growth factor I expression is essential for Purkinje neuron survival at birth
Published in Cell death and differentiation (01-01-2011)“…IGF1, an anabolic and neuroprotective factor, promotes neuronal survival by blocking apoptosis. It is released into the bloodstream by the liver, or…”
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2
Myostatin and insulin-like growth factors in uremic sarcopenia: the yin and yang in muscle mass regulation
Published in Kidney international (01-08-2006)“…Myostatin and the insulin-like growth factors (IGF-I and -II) play inhibitory and stimulatory roles, respectively, in the development and regulation of…”
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3
Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors
Published in Physiological reviews (01-10-1996)“…The insulin-like growth factors (IGFs), IGF-I and IGF-II, comprise a conserved pair of secreted proteins with diverse effects on growth, development, and…”
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4
Insulin-Like Growth Factor-Mediated Muscle Cell Survival: Central Roles for Akt and Cyclin-Dependent Kinase Inhibitor p21
Published in Molecular and Cellular Biology (01-12-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
A Calcineurin-NFATc3-Dependent Pathway Regulates Skeletal Muscle Differentiation and Slow Myosin Heavy-Chain Expression
Published in Molecular and Cellular Biology (01-09-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
PL08 Deconstructing muscle differentiation: defining insulin-like growth factor actions in muscle development and repair
Published in Growth hormone & IGF research (01-10-2012)Get full text
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OR5,30 Distinct epigenetic actions of growth hormone and Stat5b
Published in Growth hormone & IGF research (2010)Get full text
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8
Loss of the imprinted IGF2/cation-independent mannose 6-phosphate receptor results in fetal overgrowth and perinatal lethality
Published in Genes & development (15-12-1994)“…Murine embryos that inherit a nonfunctional insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor (Igf2r) gene from their fathers are…”
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Rapid changes in nuclear protein tyrosine phosphorylation after growth hormone treatment in vivo. Identification of phosphorylated mitogen-activated protein kinase and STAT91
Published in The Journal of biological chemistry (18-03-1994)“…Growth hormone (GH) plays a central role in regulating growth and intermediary metabolism in vertebrates, although the mechanisms by which GH initiates these…”
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10
"Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II
Published in The Journal of biological chemistry (25-08-1991)“…Differentiation of muscle cells to form postmitotic myotubes is usually viewed as being negatively controlled by medium components, sometimes designated…”
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11
Human growth disorders: molecular genetics of the growth hormone-insulin-like growth factor I axis
Published in Acta Paediatrica (01-02-1999)“…Rotwein P. Human growth disorders: molecular genetics of the growth hormone‐insulin‐like growth factor I axis. Acta Paidiatr 1999; Suppl 428: 148–51…”
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12
Mosaic evolution of the insulin-like growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene
Published in The Journal of biological chemistry (05-06-1987)“…Insulin-like growth factor I (IGF-I) plays a major role in mammalian growth and regenerative processes as a mediator of many of the biological effects of…”
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13
Two Insulin-Like Growth Factor I Messenger RNAs are Expressed in Human Liver
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1986)“…Through use of a synthetic oligonucleotide probe, human insulin-like growth factor I (IGF-I) cDNA clones were isolated from a liver library. Two types of cDNAs…”
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14
Structure of the chicken insulin-like growth factor I gene reveals conserved promoter elements
Published in The Journal of biological chemistry (25-05-1991)“…Insulin-like growth factor I plays a major role in cellular growth by mediating many of the actions of growth hormone. In mammals, IGF-I gene expression is…”
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15
Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth
Published in The American journal of physiology (01-07-1990)“…We have investigated the hypothesis that there is local regulation of insulin-like growth factor (IGF) gene expression during skeletal muscle growth…”
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Characterization of the Human Growth Hormone Receptor Gene and Demonstration of a Partial Gene Deletion in Two Patients with Laron-Type Dwarfism
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1989)“…Laron-type dwarfism is an autosomal recessive genetic disorder that is characterized by high levels of growth hormone and low levels of insulin-like growth…”
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Insulin-like Growth Factor Binding Protein-5 Modulates Muscle Differentiation through an Insulin-like Growth Factor-Dependent Mechanism
Published in The Journal of cell biology (01-05-1996)“…The insulin-like growth factor binding proteins (IGFBPs) are a family of six secreted proteins which bind to and modulate the actions of insulin-like growth…”
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CCAAT/enhancer-binding protein delta activates insulin-like growth factor-I gene transcription in osteoblasts. Identification of a novel cyclic AMP signaling pathway in bone
Published in The Journal of biological chemistry (12-12-1997)“…Insulin-like growth factor-I (IGF-I) plays a key role in skeletal growth by stimulating bone cell replication and differentiation. We previously showed that…”
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19
Differential Expression of Insulin-Like Growth Factor Genes in Rat Central Nervous System
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1988)“…A sensitive solution-hybridization assay was used to investigate the expression of genes encoding insulin-like growth factors I and II (IGF-I and -II) in the…”
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Rapid activation of insulin-like growth factor binding protein-5 gene transcription during myoblast differentiation
Published in Molecular endocrinology (Baltimore, Md.) (01-07-1995)“…Insulin-like growth factor binding proteins (IGFBPs) comprise a family of secreted proteins that bind insulin-like growth factors-I and -II (IGF-I and -II)…”
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