Search Results - "Rotterova, Aneta"
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C‑3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10
Published in ACS omega (12-03-2024)“…17β-HSD10 is a mitochondrial enzyme that catalyzes the steroidal oxidation of a hydroxy group to a keto group and, thus, is involved in maintaining steroid…”
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Correction to “C‑3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10”
Published in ACS omega (09-04-2024)“…[This corrects the article DOI: 10.1021/acsomega.3c10148.]…”
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Physiologically relevant fluorescent assay for identification of 17β-hydroxysteroid dehydrogenase type 10 inhibitors
Published in Journal of neurochemistry (01-10-2023)“…Mitochondrial enzyme 17β-hydroxysteroid dehydrogenase type 10 (HSD10) is a potential molecular target for treatment of mitochondrial-related disorders such as…”
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Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation
Published in European journal of medicinal chemistry (05-10-2023)“…17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a multifunctional mitochondrial enzyme and putative drug target for the treatment of various…”
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Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity
Published in ACS medicinal chemistry letters (14-12-2023)“…Multifunctional mitochondrial enzyme 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a potential drug target for the treatment of various pathologies…”
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