Search Results - "Rottenberg, S."

SP-0385: The study of therapy resistance in genetically engineered mouse models for BRCA1-mutated breast cancer by Rottenberg, S, Barazas, M, Jonkers, J, Borst, G

Get full text

PO-496 Loss of PARG drives PARP inhibitor resistance in BRCA2-deficient mouse mammary tumours by Gogola, E, Jonkers, J, Rottenberg, S

“…IntroductionInhibitors of poly(ADP-ribose) polymerase (PARP) have recently entered the clinic for the treatment of homologous recombination (HR)-deficient…”
Get full text

Thymoma-associated Exfoliative Dermatitis in Cats by Rottenberg, S., von Tscharner, C., Roosje, P. J.

“…Five cases of exfoliative dermatitis in cats were presented from 1996 to 2002 in which a feline thymoma was found by postmortem or postsurgical examination…”
Get full text

Genetically Enigineered Mouse Models and High Precision Fractionated Radiation Therapy to Unravel Mechanisms of Irradiation Escape by Borst, G, Barazas, M, Gasparini, A, Sol, W, Jonkers, J, Verheij, M, Sonke, J, Rottenberg, S

Get full text

Using BRCA1/2-Deficient Mouse Mammary Tumors and μIGRT to Investigate Underlying Mechanisms Causing Radioresistance by Borst, G, Gasparini, A, Sol, W, Kersbergen, A, Jonkers, J, Verheij, M, Sonke, J, Rottenberg, S

Get full text

Bacillus anthracis as a cause of bovine abortion - a necropsy case requiring special biosafety measures by Dettwiler, M, Mehinagic, K, Gobeli Brawand, S, Thomann, A, Feyer, S, Hüsser, L, Theubet, G, Gigandet, J, Rottenberg, S, Posthaus, H

“…In spring 2017, the first case of bovine anthrax in 20 years in Switzerland occurred in the canton of Jura. Carcasses of anthrax-deceased animals should not be…”
Get more information

169: Homologous recombination deficiency and radio-curability in mouse models for BRCA1/2-deficient breast cancer by Rottenberg, S, Borst, G, Gasparini, A, Barazas, M, Guyader, C, Sol, W, Kersbergen, A, Verheij, M, Sonke, J.J

Get full text

OC-0487: Genetically engineered breast cancer mouse models to explore and target radioresistance by Borst, G, Coackley, C, Yucel, H, Guyader, C, Berlin, A, Sonke, J.J, Verheij, M, Jonkers, J, Rottenberg, S, Bristow, R

Get full text

PO-0758: Modelling radiotherapy escape using BRCA1/2-def mouse mammary tumors and image-guided irradiation by Borst, G.R, Gasparini, A, Sol, W, Kersbergen, A, Jonkers, J, Verheij, M, Sonke, J.J, Rottenberg, S

Get full text

PO-019 Phosphoproteomics to characterise DNA damage response in mouse mammary tumours of different PARP inhibitor susceptibility by Rolfs, F, Gogola, E, Piersma, S, Pham, T, Knol, J, Rottenberg, S, Jonkers, J, Jimenez, C

“…IntroductionTriple negative breast cancers show very poor prognosis, with only limited treatment options. A subgroup of these tumours is deficient in…”
Get full text

381 INVITED Preclinical Evaluation of PARP Inhibitors in Mouse Models of Human Breast Cancer by Rottenberg, S, Jaspers, J.E, Drost, R, Bouwman, P, O'Connor, M.J, Borst, P, Jonkers, J

Get full text

AI-driven quantification of Cryptosporidium spp in the intestine of infant mice by Goepfert, C., Dale, M., Valenti, A.G., Klebic, I., Franzen, J., Siffert, M., Rottenberg, S., Olias, P.

Get full text

Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps by Paes Dias, Mariana, Tripathi, Vivek, van der Heijden, Ingrid, Cong, Ke, Manolika, Eleni-Maria, Bhin, Jinhyuk, Gogola, Ewa, Galanos, Panagiotis, Annunziato, Stefano, Lieftink, Cor, Andújar-Sánchez, Miguel, Chakrabarty, Sanjiban, Smith, Graeme C.M., van de Ven, Marieke, Beijersbergen, Roderick L., Bartkova, Jirina, Rottenberg, Sven, Cantor, Sharon, Bartek, Jiri, Ray Chaudhuri, Arnab, Jonkers, Jos

“…Inhibitors of poly(ADP-ribose) (PAR) polymerase (PARPi) have entered the clinic for the treatment of homologous recombination (HR)-deficient cancers. Despite…”
Get full text

CRISPR/Cas9: A useful tool to study the pathogenesis of the equine sarcoid? by Monod, A., Koch, C., Rottenberg, S., Gerber, V., Hahn, K.

Get full text

Bacillus anthracis as a Cause of Bovine Abortion – A Challenging Case Regarding Diagnosis and Biosafety by Dettwiler, M., Mehinagic, K., Brawand, S.Gobeli, Rottenberg, S., Posthaus, H.

Get full text

Functional Genetic Screens to Dissect the Essentialome of Disease by Woods, K., Dettwiler, M., Inglebert, M., Maurizio, M., Olias, P., Doench, J., Rottenberg, S.

Get full text

BRCA-deficient mouse mammary tumour organoids as a rapid tool to study anti-cancer drug resistance by Rottenberg, S., Duarte, A., Duarte, E., Francica, P., Mutlu, M., Blatter, S., Sachs, N., Clevers, H., Jonkers, J.

Get full text

Targeting G0-like Residual Cells in a Mouse Model for BRCA1-deficient Mammary Tumours by Blatter, S., Regenscheit, N., Guyader, C., Küçükosmanoğlu, A., de Visser, K., Borst, P., Rottenberg, S.

Get full text

Targeting drug tolerance of residual BRCA1-mutated mouse mammary tumours by Blatter, S., Pajic, M., Guyader, C., Gonggrijp, M., Kersbergen, A., Küçükosmanoğlu, A., Sol, W., Drost, R., Jonkers, J., Borst, P., Rottenberg, S.

Get full text

PO-494 Using functional genetic screens to understand resistance to PARPi in BRCA-deficient tumours by Dias, M., Gogola, E., Bhin, J., Rolfs, F., Rottenberg, S., Jonkers, J.

“…Error-free repair of double-strand DNA breaks is achieved by homologous recombination (HR), and both BRCA1 and BRCA2 are crucial for this process. Inactivating…”
Get full text