Search Results - "Rotstein, H."

Fluorine-18-Labeled Fluorescent Dyes for Dual-Mode Molecular Imaging by Munch, Maxime, Rotstein, Benjamin H, Ulrich, Gilles

“…Recent progress realized in the development of optical imaging (OPI) probes and devices has made this technique more and more affordable for imaging studies…”
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Small Heterocycles in Multicomponent Reactions by Rotstein, Benjamin H, Zaretsky, Serge, Rai, Vishal, Yudin, Andrei K

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A low cost and open access system for rapid synthesis of large volumes of gold and silver nanoparticles by Ross, Alex, Muñoz, Marcelo, Rotstein, Benjamin H., Suuronen, Erik J., Alarcon, Emilio I.

“…Rapid synthesis of nanomaterials in scalable quantities is critical for accelerating the discovery and commercial translation of nanoscale-based technologies…”
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Diagnostic accuracy of 3-T magnetic resonance imaging with 3D T1 VIBE versus computer tomography in pars stress fracture of the lumbar spine by Ang, E. C., Robertson, A. F., Malara, F. A., O’Shea, T., Roebert, J. K., Schneider, M. E., Rotstein, A. H.

“…Objective To compare the diagnostic accuracy of 3-T magnetic resonance imaging (MRI) with thin-slice 3D T1 VIBE sequence to 128-slice computer tomography (CT)…”
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Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB by Liang, Steven H., Wang, Lu, Stephenson, Nickeisha A., Rotstein, Benjamin H., Vasdev, Neil

“…Non-activated (electron-rich and/or sterically hindered) arenes are prevalent chemical scaffolds in pharmaceuticals and positron emission tomography (PET)…”
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Interobserver and intraobserver variability of glenoid track measurements by Schneider, Adrian K., FMH(Orth), MD, Hoy, Gregory A., MBBS, Dip Anat., FRACS(Orth), Ek, Eugene T., MBBS(Hons), PhD, FRACS(Orth), Rotstein, Andrew H., MBBS, FRANZCR, Tate, Julie, BSc(Hons), PgCert(CT), Taylor, David McD, MBBS, MD, MPH, DRCOG, FACEM, Evans, Matthew C., MBBS, FRACS(Orth)

“…Background A method of assessing combined glenoid and humeral bone loss in traumatic shoulder instability with an associated treatment protocol was recently…”
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HELM: A Hierarchical Notation Language for Complex Biomolecule Structure Representation by Zhang, Tianhong, Li, Hongli, Xi, Hualin, Stanton, Robert V, Rotstein, Sergio H

“…When biological macromolecules are used as therapeutic agents, it is often necessary to introduce non-natural chemical modifications to improve their…”
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Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase by Wang, Lu, Mori, Wakana, Cheng, Ran, Yui, Joji, Hatori, Akiko, Ma, Longle, Zhang, Yiding, Rotstein, Benjamin H, Fujinaga, Masayuki, Shimoda, Yoko, Yamasaki, Tomoteru, Xie, Lin, Nagai, Yuji, Minamimoto, Takafumi, Higuchi, Makoto, Vasdev, Neil, Zhang, Ming-Rong, Liang, Steven H

“…Monoacylglycerol lipase (MAGL) is a 33 kDa member of the serine hydrolase superfamily that preferentially degrades 2-arachidonoylglycerol (2-AG) to arachidonic…”
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Conformational Modulation of in Vitro Activity of Cyclic RGD Peptides via Aziridine Aldehyde-Driven Macrocyclization Chemistry by Roxin, Áron, Chen, Juan, Scully, Conor C. G, Rotstein, Benjamin H, Yudin, Andrei K, Zheng, Gang

“…Here, we demonstrate a conjugation strategy whereby cyclic RGD-containing macrocycles are prepared using aziridine aldehydes, isocyanides, and linear peptides,…”
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Synthesis of [11C]Bexarotene by Cu-Mediated [11C]Carbon Dioxide Fixation and Preliminary PET Imaging by Rotstein, Benjamin H, Hooker, Jacob M, Woo, Jiyeon, Collier, Thomas Lee, Brady, Thomas J, Liang, Steven H, Vasdev, Neil

“…Bexarotene (Targretin) is a retinoid X receptor (RXR) agonist that has applications for treatment of T cell lymphoma and proposed mechanisms of action in…”
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Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque by Holland, Jason P., Liang, Steven H., Rotstein, Benjamin H., Collier, Thomas L., Stephenson, Nickeisha A., Greguric, Ivan, Vasdev, Neil

“…Alzheimer's disease (AD) and related dementias show increasing clinical prevalence, yet our understanding of the etiology and pathobiology of disease‐related…”
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Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics by Rotstein, Benjamin H., Stephenson, Nickeisha A., Vasdev, Neil, Liang, Steven H.

“…Fluorine-18 ( t ½ =109.7 min) is the most commonly used isotope to prepare radiopharmaceuticals for molecular imaging by positron emission tomography (PET)…”
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Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics by Rotstein, Benjamin H., Stephenson, Nickeisha A., Vasdev, Neil, Liang, Steven H.

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Comparison of corticosteroid, autologous blood or sclerosant injections for chronic tennis elbow by Branson, R, Naidu, K, du Toit, C, Rotstein, A.H, Kiss, R, McMillan, D, Fooks, L, Coombes, B.K, Vicenzino, B

“…Abstract Objectives To compare three different ultrasound-guided injections for chronic tennis elbow Design Assessor-blinded, randomized controlled comparative…”
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Preclinical PET Neuroimaging of [11C]Bexarotene by Rotstein, Benjamin H., Placzek, Michael S., Krishnan, Hema S., Pekošak, Aleksandra, Collier, Thomas Lee, Wang, Changning, Liang, Steven H., Burstein, Ethan S., Hooker, Jacob M., Vasdev, Neil

“…Activation of retinoid X receptors (RXRs) has been proposed as a therapeutic mechanism for the treatment of neurodegeneration, including Alzheimer's and…”
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Fast Carbon Isotope Exchange of Carboxylic Acids Enabled by Organic Photoredox Catalysis by Kong, Duanyang, Munch, Maxime, Qiqige, Qiqige, Cooze, Christopher J. C, Rotstein, Benjamin H, Lundgren, Rylan J

“…Carbazole/cyanobenzene photocatalysts promote the direct isotopic carboxylate exchange of C­(sp3) acids with labeled CO2. Substrates that are not compatible…”
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Practical Radiosynthesis and Preclinical Neuroimaging of [11C]isradipine, a Calcium Channel Antagonist by Rotstein, Benjamin H, Liang, Steven H, Belov, Vasily V, Livni, Eli, Levine, Dylan B, Bonab, Ali A, Papisov, Mikhail I, Perlis, Roy H, Vasdev, Neil

“…In the interest of developing in vivo positron emission tomography (PET) probes for neuroimaging of calcium channels, we have prepared a carbon-11 isotopologue…”
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PET and SPECT Tracers for Myocardial Perfusion Imaging by Klein, Ran, Celiker-Guler, Emel, Rotstein, Benjamin H., deKemp, Robert A.

“…Coronary artery disease has been the leading cause of death since the 1960s, which has motivated the research and development of myocardial perfusion imaging…”
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Intramolecular Friedel‐Crafts Acylation of [11C]Isocyanates Enabling the Radiolabeling of [carbonyl‐11C]DPQ by Ozenil, Marius, Kogler, Lukas, Mair, Braeden A., Hacker, Marcus, Wadsak, Wolfgang, Rotstein, Benjamin H., Pichler, Verena

“…α,β‐aromatic lactams are highly abundant in biologically active molecules, yet so far they cannot be radiolabeled with short‐lived (t1/2=20.3 min), β+‐decaying…”
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Synthesis and Evaluation of [11C]MCC950 for Imaging NLRP3-Mediated Inflammation in Atherosclerosis by Ismailani, Uzair S., Buchler, Ariel, MacMullin, Nicole, Abdirahman, Faduma, Adi, Myriam, Rotstein, Benjamin H.

“…Overexpression of the NLRP3 inflammasome has been attributed to the progressive worsening of a multitude of cardiovascular inflammatory diseases such as…”
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