Search Results - "Rotolo, Renee"

The Psychopharmacology of Effort-Related Decision Making: Dopamine, Adenosine, and Insights into the Neurochemistry of Motivation by Salamone, John D, Correa, Mercè, Ferrigno, Sarah, Yang, Jen-Hau, Rotolo, Renee A, Presby, Rose E

“…Effort-based decision making is studied using tasks that offer choices between high-effort options leading to more highly valued reinforcers versus…”
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Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research by Salamone, John D, Correa, Merce, Yang, Jen-Hau, Rotolo, Renee, Presby, Rose

“…Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing…”
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Lipopolysaccharide-induced changes in effort-related motivational function: Interactions with 2-deoxyglucose by Presby, Rose E., Rotolo, Renee A., Katz, Sydney, Sarwat, Zoha, Correa, Merce, Salamone, John D.

“…•The effects of lipopolysaccharide (LPS) on effort-based choice were assessed in rats.•LPS reduced lever pressing for preferred food pellets but did not affect…”
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Effort-related effects of chronic administration of the DA D2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonist istradefylline by Rotolo, Renee A., Ecevitoglu, Alev, Presby, Rose E., Lindgren, Hanna, Mombereau, Cedric, Nicholas, Cyrene, Moore, Alana, Edelstein, Gayle A., Correa, Merce, Salamone, John D.

“…Rationale Long-acting antipsychotics such as haloperidol decanoate are becoming more commonly used. Long-acting depot formulations have several advantages, but…”
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The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology by Rotolo, Renee A., Presby, Rose E., Tracy, Olivia, Asar, Sokaina, Yang, Jen-Hau, Correa, Merce, Murray, Fraser, Salamone, John D.

“…Depressed individuals suffer from effort-related motivational symptoms such as anergia and fatigue, which are resistant to treatment with many common…”
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Prophylactic exposure to oral riluzole reduces the clinical severity and immune-related biomarkers of experimental autoimmune encephalomyelitis by Rotolo, Renee A., Demuro, Jennifer, Drummond, Gregory, Little, Casey, Johns, Lennart D., Betz, Adrienne J.

“…Glutamate-mediated excitotoxicity and immune cell infiltration are hallmarks of multiple sclerosis. The glutamate release inhibitor, riluzole (RIL), has been…”
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Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia by Salamone, John D., Ecevitoglu, Alev, Carratala-Ros, Carla, Presby, Rose E., Edelstein, Gayle A., Fleeher, Reileigh, Rotolo, Renee A., Meka, Nicolette, Srinath, Sonya, Masthay, Jamie C., Correa, Merce

“…Instrumental behavior is a very complex and multifaceted process. Behavioral output during instrumental performance is influenced by a variety of factors,…”
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Lisdexamfetamine suppresses instrumental and consummatory behaviors supported by foods with varying degrees of palatability: Exploration of a binge-like eating model by Presby, Rose E., Rotolo, Renee A., Yang, Jen-Hau, Correa, Merce, Salamone, John D.

“…Diets high in sugar or fat are associated with multiple health conditions, including binge eating disorder (BED). BED affects approximately 2% of the US adult…”
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Potential therapeutics for effort-related motivational dysfunction: assessing novel atypical dopamine transport inhibitors by Ecevitoglu, Alev, Meka, Nicolette, Rotolo, Renee A, Edelstein, Gayle A, Srinath, Sonya, Beard, Kathryn R, Carratala-Ros, Carla, Presby, Rose E, Cao, Jianjing, Okorom, Amarachi, Newman, Amy H, Correa, Mercè, Salamone, John D

“…People with depression and other neuropsychiatric disorders can experience motivational dysfunctions such as fatigue and anergia, which involve reduced…”
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Behavioral and dopamine transporter binding properties of the modafinil analog (S, S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding by Rotolo, Renee A., Kalaba, Predrag, Dragacevic, Vladimir, Presby, Rose E., Neri, Julia, Robertson, Emily, Yang, Jen-Hau, Correa, Merce, Bakulev, Vasiliy, Volkova, Natalia N., Pifl, Christian, Lubec, Gert, Salamone, John D.

“…Rationale Atypical dopamine (DA) transport blockers such as modafinil and its analogs may be useful for treating motivational symptoms of depression and other…”
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Pharmacological studies of effort-related decision making using mouse touchscreen procedures: effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction by Yang, Jen-Hau, Presby, Rose E., Jarvie, Adam A., Rotolo, Renee A., Fitch, R. Holly, Correa, Mercè, Salamone, John D.

“…Rationale Effort-based decision-making tasks offer animals choices between preferred reinforcers that require high effort to obtain vs. low effort/low reward…”
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Effects of the atypical antipsychotic and D3/D2 dopamine partial agonist cariprazine on effort-based choice behavior: implications for modeling avolition by Ecevitoglu, Alev, Edelstein, Gayle A., Presby, Rose E., Rotolo, Renee A., Yang, Jen-Hau, Quiles, Taina, Okifo, Kevin, Conrad, Ryan T., Kovach, Ashley, Correa, Merce, Salamone, John D.

“…Rationale Cariprazine is an atypical antipsychotic that acts as a D3/D2 receptor partial agonist. In addition to treating positive symptoms of schizophrenia,…”
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Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine by Presby, Rose E., Rotolo, Renee A., Hurley, Erin M., Ferrigno, Sarah M., Murphy, Cayla E., McMullen, Haley P., Desai, Pranally A., Zorda, Emma M., Kuperwasser, Felicita B., Carratala-Ros, Carla, Correa, Merce, Salamone, John D.

“…Selective serotonin transport (SERT) inhibitors such as fluoxetine are the most commonly prescribed treatments for depression. Although efficacious for many…”
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Effort-related decision making in humanized COMT mice: Effects of Val158Met polymorphisms and possible implications for negative symptoms in humans by Yang, Jen-Hau, Presby, Rose E., Cayer, Suzanne, Rotolo, Renee A., Perrino, Peter A., Fitch, R. Holly, Correa, Merce, Chesler, Elissa J., Salamone, John D.

“…Catechol-o-methyltransferase (COMT) is an enzyme that metabolizes catecholamines, and is crucial for clearance of dopamine (DA) in prefrontal cortex. Val158Met…”
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The dopamine depleting agent tetrabenazine alters effort-related decision making as assessed by mouse touchscreen procedures by Yang, Jen-Hau, Presby, Rose E., Rotolo, Renee A., Quiles, Taina, Okifo, Kevin, Zorda, Emma, Fitch, Roslyn Holly, Correa, Mercè, Salamone, John D.

“…Rationale Effort-based decision-making tasks allow animals to choose between preferred reinforcers that require high effort to obtain vs. low-effort/low reward…”
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The Novel Atypical Dopamine Uptake Inhibitor (S) -CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding by Rotolo, Renee A, Dragacevic, Vladimir, Kalaba, Predrag, Urban, Ernst, Zehl, Martin, Roller, Alexander, Wackerlig, Judith, Langer, Thierry, Pistis, Marco, De Luca, Maria Antonietta, Caria, Francesca, Schwartz, Rebecca, Presby, Rose E, Yang, Jen-Hau, Samels, Shanna, Correa, Merce, Lubec, Gert, Salamone, John D

“…Animal studies of effort-based choice behavior are being used to model effort-related motivational dysfunctions in humans. With these procedures, animals are…”
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Effects of the dopamine depleting agent tetrabenazine on detailed temporal parameters of effort‐related choice responding by Ren, Naxin, Carratala‐Ros, Carla, Ecevitoglu, Alev, Rotolo, Renee A., Edelstein, Gayle A., Presby, Rose E., Stevenson, Ian H., Chrobak, James J., Salamone, John D.

“…The dopamine‐depleting agent tetrabenazine alters effort‐based choice, suppressing food‐reinforced behaviors with high response requirements, while increasing…”
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Behavioral Activation, Effort-Based Choice, and Elasticity of Demand for Motivational Stimuli: Basic and Translational Neuroscience Approaches by Salamone, John D, Correa, Mercè, Yohn, Samantha E, Yang, Jen-Hau, Somerville, Matthew, Rotolo, Renee A, Presby, Rose E

“…Behavioral activation and effort-related processes are fundamental components of the construct of motivation. Motivated behavior is often characterized by…”
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Effort-related effects of chronic administration of the DA D.sub.2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonist istradefylline by Rotolo, Renee A, Ecevitoglu, Alev, Presby, Rose E, Lindgren, Hanna, Mombereau, Cedric, Nicholas, Cyrene, Moore, Alana, Edelstein, Gayle A, Correa, Merce, Salamone, John D

“…Rationale Long-acting antipsychotics such as haloperidol decanoate are becoming more commonly used. Long-acting depot formulations have several advantages, but…”
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Effort-Related Motivational Effects of Novel Atypical Dopamine Transport Inhibitors: Implications for Psychopathology by Salamone, John, Rotolo, Renee, Ecevitoglu, Alev, Presby, Rose, Meka, Nicolette, Edelstein, Gayle, Srinath, Sonya, Carratala-Ros, Carla, Arias, Edgar, Correa, Merce

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