Search Results - "Roti, G"

Genetic and proteomic approaches to identify cancer drug targets by Roti, G, Stegmaier, K

“…While target-based small-molecule discovery has taken centre-stage in the pharmaceutical industry, there are many cancer-promoting proteins not easily…”
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Differentially regulated high-throughput CT imaging features correlate to distinct tumor immune contextures portraying a radiomic signature with prognostic impact on surgically resected NSCLC by Mazzaschi, G., Quaini, F., Milanese, G., Madeddu, D., Bocchialini, G., Ampollini, L., Gnetti, L., Lagrasta, C., Silva, M., Roti, G., Sverzellati, N., Tiseo, M.

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Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations by GORELLO, P, CAZZANIGA, G, LO COCO, F, BIONDI, A, SAGLIO, G, MECUCCI, C, FALINI, B, ALBERTI, F, DELL'ORO, M. G, GOTTARDI, E, SPECCHIA, G, ROTI, G, ROSATI, R, MARTELLI, M. F, DIVERIO, D

“…Mutations in exon 12 of the nucleophosmin (NPM1) gene occur in about 60% of adult AML with normal karyotype. By exploiting a specific feature of NPM1 mutants,…”
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P336: A CHEMOTRANSCRIPTOMIC SCREENING IDENTIFIES THE REVERSAL OF GLUCOCORTICOID RESISTANCE IN NOTCH1 MUTATED T‐ALL by Pagliaro, L., Moron Dalla Tor, L., Federica, V., Andrei, P., Monica, L., Kleissle, S., Neuenschwander, M., Gherli, A., Cerretani, E., D'Antuono, A., Simoncini, E., Montanaro, A., Roti, G.

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A new NDE1 PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome by La Starza, R, Rosati, R, Roti, G, Gorello, P, Bardi, A, Crescenzi, B, Pierini, V, Calabrese, O, Baens, M, Folens, C, Cools, J, Marynen, P, Martelli, M F, Mecucci, C, Cuneo, A

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Different genomic imbalances in low- and high-grade HCV-related lymphomas by Matteucci, C, Bracci, M, Barba, G, Carbonari, M, Casato, M, Visentini, M, Pulsoni, A, Varasano, E, Roti, G, Starza, R La, Crescenzi, B, Martelli, M F, Fiorilli, M, Mecucci, C

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Cryptic chromosome 9q34 deletion generates TAF-I{alpha}/CAN and TAF-I{beta}/CAN fusion transcripts in acute myeloid leukemia by Rosati, Roberto, La Starza, Roberta, Barba, Gianluca, Gorello, Paolo, Pierini, Valentina, Matteucci, Caterina, Roti, Giovanni, Crescenzi, Barbara, Romoli, Silvia, Aloisi, Teresa, Aversa, Franco, Martelli, Massimo Fabrizio, Mecucci, Cristina

“…From the Hematology and Bone Marrow Transplantation Unit, University of Perugia, 06122 Perugia, Italy Correspondence: Cristina Mecucci, Hematology and Bone…”
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C022 NPM1 monoallelic deletion in a subgroup of MDS/AML with del (5q) or monosomy 5 and complex karyotype by La Starza, R, Roti, G, Brandimarte, L, Varasano, E, Arcioni, F, Pierini, A, Crescenzi, B, Diverio, D, Guglielmini, G, Martelli, M.F, Aventin, A, Mecucci, C

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2315P Clinical and blood immune-inflammatory profiling to decode different patterns of acquired resistance in immunotherapy treated NSCLC patients by Mazzaschi, G., Cardinale, E., Pluchino, M., Monica, G., Lorusso, B., D'Agnelli, S., Trentini, F., Tamarozzi, P., Dalla Tor, L. Moron, Verzè, M., Minari, R., Bordi, P., Perrone, F., Leonetti, A., Gnetti, L., Roti, G., Quaini, F., Sverzellati, N., Tiseo, M.

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17P Dynamic changes of CT-radiomic and systemic immune-inflammatory features predict the response to immune checkpoint inhibitors in advanced NSCLC patients by Mazzaschi, G., Milanese, G., Moron Dalla Tor, L., Leo, L., Balbi, M., Trentini, F., Manini, M., Pavone, C., Silva, M., Ledda, R.E., Minari, R., Bordi, P., Buti, S., Leonetti, A., Roti, G., Quaini, F., Sverzellati, N., Tiseo, M.

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1061P Static and dynamic tracking of radiomic and immunophenotypic features predicts the benefit of immune checkpoint inhibitors in advanced NSCLC by Mazzaschi, G., Moron Dalla Tor, L., Balbi, M., Milanese, G., Tognazzi, D., Lorusso, B., Trentini, F., Di Rienzo, G., Verzè, M., Pluchino, M., Minari, R., Leo, L., Gnetti, L., Bordi, P., Leonetti, A., Ampollini, L., Roti, G., Quaini, F., Sverzellati, N., Tiseo, M.

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1982PD - Identification of a radio-immune signature with high prognostic value in surgically resected NSCLC by Mazzaschi, G., Quaini, F., Milanese, G., Gnetti, L., Bocchialini, G., Ampollini, L., Minari, R., Silva, M., Sverzellati, N., Roti, G., Tiseo, M.

“…The role of radiomics against clinical and histologic standard has been repeatedly demonstrated, although the integration of high-throughput imaging into a…”
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1982PDIdentification of a radio-immune signature with high prognostic value in surgically resected NSCLC by Mazzaschi, G, Quaini, F, Milanese, G, Gnetti, L, Bocchialini, G, Ampollini, L, Minari, R, Silva, M, Sverzellati, N, Roti, G, Tiseo, M

“…Abstract Background The role of radiomics against clinical and histologic standard has been repeatedly demonstrated, although the integration of…”
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Identification of a radio-immune signature with high prognostic value in surgically resected NSCLC by Mazzaschi, G., Quaini, F., Milanese, G., Gnetti, L., Bocchialini, G., Ampollini, L., Minari, R., Silva, M., Sverzellati, N., Roti, G., Tiseo, M.

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2ODifferentially regulated high-throughput CT imaging features correlate to distinct tumor immune contextures portraying a radiomic signature with prognostic impact on surgically resected NSCLC by Mazzaschi, G, Quaini, F, Milanese, G, Madeddu, D, Bocchialini, G, Ampollini, L, Gnetti, L, Lagrasta, C, Silva, M, Roti, G, Sverzellati, N, Tiseo, M

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1OAdvanced CT imaging features reflect distinct tissue immune profiles and exhibit high prognostic impact on NSCLC by Mazzaschi, G, Pagano, P, Milanese, G, Madeddu, D, Falco, A, Armani, G, Bocchialini, G, Marturano, D, Ampollini, L, Lorusso, B, Lagrasta, C, Sverzellati, N, Silva, M, Tiseo, M, Quaini, F, Roti, G

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Advanced CT imaging features reflect distinct tissue immune profiles and exhibit high prognostic impact on NSCLC by Mazzaschi, G., Pagano, P., Milanese, G., Madeddu, D., Falco, A., Armani, G., Bocchialini, G., Marturano, D., Ampollini, L., Lorusso, B., Lagrasta, C., Sverzellati, N., Silva, M., Tiseo, M., Quaini, F., Roti, G.

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227P Sexual dimorphism in immune profile of early and advanced NSCLC by Mazzaschi, G., Indries, P., Monica, G., Pluchino, M., Lorusso, B., D'Agnelli, S., Bocchialini, G., Trentini, F., Dalla Tor, L. Moron, Verzè, M., Minari, R., Perrone, F., Bordi, P., Leonetti, A., Gnetti, L., Ampollini, L., Roti, G., Quaini, F., Sverzellati, N., Tiseo, M.

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238P Exploring blood immune cell dynamics to unravel the immunomodulatory effect of radiotherapy in NSCLC patients undergoing immune checkpoint inhibitors by Mazzaschi, G., Tamarozzi, P., Lorusso, B., Verzè, M., Pluchino, M., Trentini, F., Dalla Valle, B., Minari, R., Perrone, F., Bordi, P., Leonetti, A., Moron Dalla Tor, L., Leo, L., Milanese, G., Balbi, M., Buti, S., Roti, G., Quaini, F., Sverzellati, N., Tiseo, M.

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Blockade of oncogenic notch1 with the new serca inhibitor cad204520 in t-cell acute lymphoblastic leukemia by M. Marchesini, A. Gherli, A. Montanaro, C. Sorrentino, L. Pagliaro, C. Rompietti, S. Kitara, F. Rizzi, D. Stilli, R. La Starza, C. Mecucci, K. Stegmaier, A.M. Lund Winter, P. Sportoletti, M. Bublitz, W. Dalby-Brown, G. Roti

“…The discovery of the P-type ATPase Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) as a bidirectional modulator of oncogenic NOTCH1 suggests an innovative…”
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