Search Results - "Rothweiler, F."

Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles by Dreis, S., Rothweiler, F., Michaelis, M., Cinatl, J., Kreuter, J., Langer, K.

“…Human serum albumin (HSA) nanoparticles represent promising drug carrier systems. Binding of cytostatics to HSA nanoparticles may diminish their toxicity,…”
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Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells by Michaelis, M, Rothweiler, F, Barth, S, Cinatl, J, van Rikxoort, M, Löschmann, N, Voges, Y, Breitling, R, von Deimling, A, Rödel, F, Weber, K, Fehse, B, Mack, E, Stiewe, T, Doerr, H W, Speidel, D, Cinatl, J

“…Six p53 wild-type cancer cell lines from infrequently p53-mutated entities (neuroblastoma, rhabdomyosarcoma, and melanoma) were continuously exposed to…”
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Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status by Michaelis, M, Rothweiler, F, Loeschmann, N, Sharifi, M, Ghafourian, T, Cinatl, J

“…Background: Enzastaurin is a PKCβ inhibitor that has been tested in clinical trials. Here, enzastaurin was tested in neuroblastoma and rhabdomyosarcoma cell…”
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Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status by Michaelis, M, Rothweiler, F, Löschmann, N, Sharifi, M, Ghafourian, T, Cinatl, J

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Flubendazole as potential anti-neuroblastoma therapy option by Michaelis, M, Agha, B, Rothweiler, F, Loeschmann, N, Voges, Y, Westermann, F, Wass, M, Cinatl, J

“…An abstract of a study by Michaelis et al on flubendazole as potential anti-neuroblastoma therapy option is presented. The study tested flubendazole for…”
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Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport by Michaelis, M, Rothweiler, F, Wurglics, M, Aniceto, N, Wiese, M, Wass, M, Ghafourian, T, Schubert-Zsilavecz, M, Cinatl, J

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Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport by Michaelis, M, Rothweiler, F, Wurglics, M, Aniceto, N, Dittrich, M, Zettl, H, Wass, M, Ghafourian, T, Schubert-Zsilavecz, M, Cinatl, J

“…Background: Pirinixic acid derivatives, a new class of drug candidates for a range of diseases, interfere with targets including PPARu, PPARy, 5-lipoxygenase…”
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138 The MDM2 Inhibitor Nutlin-3 But Not the p53 Activator RITA Induces Loss-of-function p53 Mutations by Michaelis, M, Rothweiler, F, Barth, S, Cinatl, J, van Rikxoort, M, von Deimling, A, Rödel, F, Speidel, D

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Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents by Michaelis, M, Rothweiler, F, Agha, B, Barth, S, Voges, Y, Löschmann, N, von Deimling, A, Breitling, R, Wilhelm Doerr, H, Rödel, F, Speidel, D, Cinatl, J

“…Adaptation of wild-type p53 expressing UKF-NB-3 cancer cells to the murine double minute 2 inhibitor nutlin-3 causes de novo p53 mutations at high frequency…”
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Correlation from undiluted vitreous cytokines of untreated central retinal vein occlusion with spectral domain optical coherence tomography by Koss, Mj, Pfister, M, Rothweiler, F, Rejdak, R, Ribeiro, R, Cinatl, J, Schubert, R, Kohnen, T, Koch, Fh

“…To correlate inflammatory and proangiogenic key cytokines from undiluted vitreous of treatment-naïve central retinal vein occlusion (CRVO) patients with SD-OCT…”
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Valproic acid induces extracellular signal-regulated kinase 1 2 activation and inhibits apoptosis in endothelial cells by Michaelis, M, Suhan, T, Michaelis, U R, Beek, K, Rothweiler, F, Tausch, L, Werz, O, Eikel, D, Zörnig, M, Nau, H, Fleming, I, Doerr, H W, Cinatl, J

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Selection of a highly invasive neuroblastoma cell population through long-term human cytomegalovirus infection by Michaelis, M, Barth, S, Breitling, R, Bruch, J, Steinberger, D, Rothweiler, F, Hackmann, K, Schröck, E, Doerr, H W, Griffin, D K, Cinatl, J, Cinatl, J

“…The human cytomegalovirus (HCMV) is suspected to increase tumour malignancy by infection of cancer and/or stroma cells (oncomodulation). So far, oncomodulatory…”
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A0542 - Preclinical assessment of integrin receptors as therapeutic targets in advanced treatment-resistant prostate cancer by Tsaur, I., Saar, M., Juengel, E., Vakhrusheva, O., Slade, K.S., Michaelis, M., Rothweiler, F., Cinatl, J., Menger, M.D., Linxweiler, J., Blaheta, R.A.

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Preclinical assessment of integrin receptors as therapeutic targets in advanced treatment-resistant prostate cancer by Tsaur, I., Saar, M., Juengel, E., Vakhrusheva, O., Slade, K.S., Michaelis, M., Rothweiler, F., Cinatl, J., Menger, M.D., Linxweiler, J., Blaheta, R.A.

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Patterns and mechanisms of resistance to cisplatin and osimertinib in penile squamous cell carcinoma by Thomas, A., Vakhrusheva, O., Michaelis, M., Cinatl, J., Rothweiler, F., Albersen, M., Haferkamp, A., Juengel, E., Tsaur, I.

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Impact of resistance to cisplatin and osimertinib on dissemination properties of penile cancer cells by Thomas, A., Huck, S., Slade, K.S., Vakhrusheva, O., Michaelis, M., Cinatl, J.J., Cinatl, J., Rothweiler, F., Haferkamp, A., Juengel, E., Tsaur, I.

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207 - Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status by Michaelis, M., Rothweiler, F., Loeschmann, N., Sharifi, M., Ghafourian, T., Cinatl, J.

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126 - Flubendazole as potential anti-neuroblastoma therapy option by Michaelis, M., Agha, B., Rothweiler, F., Loeschmann, N., Voges, Y., Westermann, F., Wass, M., Cinatl, J.

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Cytokine determination from vitreous samples in retinal vascular diseases by Pfister, M, Koch, F H, Cinatl, J, Rothweiler, F, Schubert, R, Singh, P, Ackermann, H, Koss, M J

“…The aim of this study was to determine cytokine levels from vitreous samples of treatment-naive patients with diabetic retinopathy (DRP), retinal vein…”
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556 - Enzastaurin inhibits ABCB1-mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status by Michaelis, M., Rothweiler, F., Löschmann, N., Sharifi, M., Ghafourian, T., Cinatl, J.

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