Search Results - "Rothman, Alex M K"
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Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension
Published in European radiology (01-09-2020)“…Objectives Computed tomography (CT) pulmonary angiography is widely used in patients with suspected pulmonary hypertension (PH). However, the diagnostic and…”
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Journal Article -
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Quantitative CT Evaluation of Small Pulmonary Vessels Has Functional and Prognostic Value in Pulmonary Hypertension
Published in Radiology (01-11-2022)“…Background The in vivo relationship between peel pulmonary vessels, small pulmonary vessels, and pulmonary hypertension (PH) is not fully understood. Purpose…”
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Establishing minimally important differences for cardiac MRI end-points in pulmonary arterial hypertension
Published in The European respiratory journal (01-08-2023)“…Cardiac magnetic resonance (CMR) is the gold standard technique to assess biventricular volumes and function, and is increasingly being considered as an…”
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Intracellular retention of mutant retinoschisin is the pathological mechanism underlying X-linked retinoschisis
Published in Human molecular genetics (15-11-2002)“…X-linked retinoschisis results in visual loss in early life with splitting within the inner retinal layers. Many missense and protein truncating mutations of…”
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MicroRNA in Pulmonary Vascular Disease
Published in Progress in Molecular Biology and Translational Science (2014)“…MicroRNA (miRNA) are short noncoding RNA that regulate gene expression by inhibiting translation or promoting degradation of target mRNA. miRNA are key…”
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Book Chapter Journal Article -
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Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood
Published in Nature communications (07-12-2021)“…Idiopathic pulmonary arterial hypertension (IPAH) is a rare but fatal disease diagnosed by right heart catheterisation and the exclusion of other forms of…”
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