Search Results - "Rothkötter, H.‐J."

Beyond the microcirculation: sequestration of infected red blood cells and reduced flow in large draining veins in experimental cerebral malaria by Oelschlegel, A. M., Bhattacharjee, R., Wenk, P., Harit, K., Rothkötter, H-J, Koch, S. P., Boehm-Sturm, P., Matuschewski, K., Budinger, E., Schlüter, D., Goldschmidt, J., Nishanth, G.

“…Sequestration of infected red blood cells (iRBCs) in the microcirculation is a hallmark of cerebral malaria (CM) in post-mortem human brains. It remains…”
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Deoxynivalenol affects cell metabolism in vivo and inhibits protein synthesis in IPEC-1 cells by Nossol, Constanze, Landgraf, Peter, Barta-Böszörmenyi, Anikó, Kahlert, Stefan, Kluess, Jeannette, Isermann, Berend, Stork, Oliver, Dieterich, Daniela C., Dänicke, Sven, Rothkötter, H.-J.

“…Deoxynivalenol is present in forage crops in concentrations that endanger animal welfare but is also found in cereal-based food. The amphipathic nature of…”
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Deoxynivalenol triggers the expression of IL-8-related signaling cascades and decreases protein biosynthesis in primary monocyte-derived cells by Nossol, Constanze, Landgraf, P., Oster, M., Kahlert, S., Barta-Böszörmenyi, A., Kluess, J., Wimmers, K., Isermann, B., Stork, O., Dieterich, D. C., Dänicke, S., Rothkötter, H.-J.

“…Humans and their immune system are confronted with mold-contaminated food and/or mold-contaminated air in daily life and indoor activities. This results in…”
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Studies on the toxicity of deoxynivalenol (DON), sodium metabisulfite, DON-sulfonate (DONS) and de-epoxy-DON for porcine peripheral blood mononuclear cells and the Intestinal Porcine Epithelial Cell lines IPEC-1 and IPEC-J2, and on effects of DON and DONS on piglets by Dänicke, S., Hegewald, Anne-Kathrin, Kahlert, S., Kluess, Jeannette, Rothkötter, H.-J., Breves, G., Döll, Susanne

“…The in vitro effects of deoxynivalenol (DON), de-epoxy-DON, DON-sulfonate (DONS) and sodium metabisulfite (Na 2S 2O 5, SBS) on porcine peripheral blood…”
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Interactions between the Fusarium toxin deoxynivalenol and lipopolysaccharides on the in vivo protein synthesis of acute phase proteins, cytokines and metabolic activity of peripheral blood mononuclear cells in pigs by Kullik, K., Brosig, B., Kersten, S., Valenta, H., Diesing, A.-K., Panther, P., Reinhardt, N., Kluess, J., Rothkötter, H.-J., Breves, G., Dänicke, S.

“…•No impact on acute phase protein synthesis and metabolic activity of lymphocytes after systemic DON application.•LPS acute iv mediates acute phase response…”
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Relationships between body temperatures and inflammation indicators under physiological and pathophysiological conditions in pigs exposed to systemic lipopolysaccharide and dietary deoxynivalenol by Tesch, T., Bannert, E., Kluess, J., Frahm, J., Hüther, L., Kersten, S., Breves, G., Renner, L., Kahlert, S., Rothkötter, H.‐J., Dänicke, S.

“…Summary We studied the constancy of the relationship between rectal and intraabdominal temperature as well as their linkage to inflammatory markers (leucocyte…”
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Deoxynivalenol, but not E. coli lipopolysaccharide, changes the response pattern of intestinal porcine epithelial cells (IPEC-J2) according to its route of application by Kluess, J.W., Kahlert, S., Kröber, A., Diesing, A.-K., Rothkötter, H.-J., Wimmers, Klaus, Dänicke, S.

“…•Susceptibility of polarised intestinal epithelial cells to deoxynivalenol and LPS studied.•Transcriptional regulation independent of site of epithelial…”
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Air–liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC) by Nossol, Constanze, Diesing, A.-K., Walk, N., Faber-Zuschratter, H., Hartig, R., Post, A., Kluess, J., Rothkötter, H.-J., Kahlert, S.

“…The specific function of the epithelium as critical barrier between the intestinal lumen and the organism’s internal microenvironment is reflected by permanent…”
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On the effects of a chronic deoxynivalenol intoxication on performance, haematological and serum parameters of pigs when diets are offered either for ad libitum consumption or fed restrictively by Goyarts, T, Dänicke, S, Rothkötter, H-J, Spilke, J, Tiemann, U, Schollenberger, M

“…Wheat infected naturally with Fusarium, contaminated mainly with deoxynivalenol (DON) (16.6 mg DON/kg), was added to a total constant wheat content of 400 g/kg…”
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The pig as a model of developmental immunology by Rothkötter, H J, Sowa, E, Pabst, R

“…There are many limitations to analyse the developing immune system in humans, thus there is need for experimental animal models to study the environmental…”
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Regulation of mucosal immune responses in effector sites by Bailey, M., Plunkett, F. J., Rothkötter, H.-J., Vega-Lopez, M. A., Haverson, K., Stokes, C. R.

“…In human disease and rodent models, immune responses in the intestinal mucosa can be damaging. Damage is characterised by villus atrophy, crypt hyperplasia and…”
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Deoxynivalenol affects the composition of the basement membrane proteins and influences en route the migration of CD16⁺ cells into the intestinal epithelium by Nossol, Constanze, Diesing, A. K, Kahlert, S, Kersten, S, Kluess, J, Ponsuksili, S, Hartig, R, Wimmers, K, Dänicke, S, Rothkötter, H. J

“…The numerous pores in the basement membrane (BM) of the intestinal villi are essential for the communication of enterocytes with cells in the lamina propria,…”
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Model for experimental revascularized laryngeal allotransplantation by Birchall, M. A., Bailey, M., Barker, E. V., Rothkötter, H.-J., Otto, K., Macchiarini, P.

“…Background: Although a human laryngeal transplant has been undertaken successfully, important questions remain that require a suitable animal model. Methods: A…”
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Dietary fiber and its role in performance, welfare, and health of pigs by Grześkowiak, Ł, Saliu, E-M, Martínez-Vallespín, B, Aschenbach, J R, Brockmann, G A, Fulde, M, Hartmann, S, Kuhla, B, Lucius, R, Metges, C C, Rothkötter, H J, Vahjen, W, Wessels, A G, Zentek, J

“…Dietary fiber (DF) is receiving increasing attention, and its importance in pig nutrition is now acknowledged. Although DF for pigs was frowned upon for a long…”
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Deoxynivalenol and E.coli lipopolysaccharide alter epithelial proliferation and spatial distribution of apical junction proteins along the small intestinal axis by Klunker, L R, Kahlert, S, Panther, P, Diesing, A-K, Reinhardt, N, Brosig, B, Kersten, S, Dänicke, S, Rothkötter, H-J, Kluess, J W

“…We investigated a proposed synergistic effect of deoxynivalenol (DON) and lipopolysaccharides (LPS) on small intestinal architecture and epithelial barrier…”
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Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role? by Gallois, M., Rothkötter, H. J., Bailey, M., Stokes, C. R., Oswald, I. P.

“…As a result of the European ban of in-feed growth-promoting antibiotics, new strategies are being developed to increase the resistance to disease in farm…”
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Myofaszial bedingte chronische Unterbauchschmerzen bei Frauen: Eine retrospektive Auswertung der Auswirkungen einer spezifischen Diagnostik und Therapie by Schwagerus, L., Dörner, K., Bender, S., Müller, K., Bitterlich, N., Rothkötter, H.‑J., Günther, O.

“…Zusammenfassung Hintergrund Die Prävalenz chronischer Unterbauchschmerzen in der Allgemeinbevölkerung von 11,8 % unterstreicht die Bedeutung dieser Erkrankung…”
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Quantification of proliferating lymphocyte subsets appearing in the intestinal lymph and the blood by THIELKE, K. H, PABST, R, ROTHKÖTTER, H. J

“…Lymphocyte emigration from the intestinal wall via lymphatics is necessary to maintain gastrointestinal immunity and also to connect the different parts of the…”
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Notfallnarkose – Vorbereitung und Assistenz im Rettungsdienst: Ein Konzept zur standardisierten Vorbereitung by Rothkötter, J.-H., Fischer, D., Schmidt-Torner, S.

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The Influence of Age and Breeding Conditions on the Number and Proliferation of Intraepithelial Lymphocytes in Pigs by H -J Rothkotter, Mollhoff, S, Pabst, R

“…The number and subset composition of intraepithelial lymphocytes (IEL) were studied in pigs in different age groups ranging from 1 day to 4.5 years. There were…”
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