Search Results - "Rother, R. P."

C5 Blockade with Conventional Immunosuppression Induces Long‐Term Graft Survival in Presensitized Recipients by Rother, R. P., Arp, J., Jiang, J., Ge, W., Faas, S. J., Liu, W., Gies, D. R., Jevnikar, A. M., Garcia, B., Wang, H.

“…We explored whether a functionally blocking anti‐C5 monoclonal antibody (mAb) combined with T‐ and B‐cell immunosuppression can successfully prevent…”
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C5 complement inhibition attenuates shock and acute lung injury in an experimental model of ruptured abdominal aortic aneurysm by Harkin, D. W., Marron, C. D., Rother, R. P., Romaschin, A., Rubin, B. B., Lindsay, T. F.

“…Background: Ruptured abdominal aortic aneurysm (RAAA) is associated with a systemic inflammatory response syndrome and multiple organ dysfunction. The…”
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Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease by Ataga, Kenneth I, Kutlar, Abdullah, Kanter, Julie, Liles, Darla, Cancado, Rodolfo, Friedrisch, João, Guthrie, Troy H, Knight-Madden, Jennifer, Alvarez, Ofelia A, Gordeuk, Victor R, Gualandro, Sandra, Colella, Marina P, Smith, Wally R, Rollins, Scott A, Stocker, Jonathan W, Rother, Russell P

“…In this yearlong trial involving patients with sickle cell disease, crizanlizumab, an antibody to P-selectin, was associated with a 45% lower rate of pain…”
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Inhibition of terminal complement: a novel therapeutic approach for the treatment of systemic lupus erythematosus by Rother, R P, Mojcik, C F, McCroskery, E W

“…The importance of the complement system in the pathophysiology of systemic lupus erythematosus (SLE) is clear although individual complement components play…”
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Inducible Costimulator Regulates Th2-Mediated Inflammation, but Not Th2 Differentiation, in a Model of Allergic Airway Disease by Tesciuba, Amanda G, Subudhi, Sumit, Rother, Russell P, Faas, Susan J, Frantz, Aric M, Elliot, David, Weinstock, Joel, Matis, Louis A, Bluestone, Jeffrey A, Sperling, Anne I

“…A novel costimulatory molecule expressed on activated T cells, inducible costimulator (ICOS), and its ligand, B7-related protein-1 (B7RP-1), were recently…”
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A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody by Rother, R P, Fodor, W L, Springhorn, J P, Birks, C W, Setter, E, Sandrin, M S, Squinto, S P, Rollins, S A

“…Type C retroviruses endogenous to various nonprimate species can infect human cells in vitro, yet the transmission of these viruses to humans is restricted…”
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Inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri by ROTHER, R. P, ROLLINS, S. A, FODOR, W. L, ALBRECHT, J.-C, SETTER, E, FLECKENSTEIN, B, SQUINTO, S. P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Keratin Peptide Inhibits Mannose-Binding Lectin by Montalto, Michael C, Collard, Charles D, Buras, Jon A, Reenstra, Wende R, McClaine, Rebecca, Gies, David R, Rother, Russell P, Stahl, Gregory L

“…Complement plays a significant role in mediating endothelial injury following oxidative stress. We have previously demonstrated that the lectin complement…”
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The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activity by Fodor, W L, Rollins, S A, Bianco-Caron, S, Rother, R P, Guilmette, E R, Burton, W V, Albrecht, J C, Fleckenstein, B, Squinto, S P

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Erythopoietin treatment during complement inhibition with eculizumab in a patient with paroxysmal nocturnal hemoglobinuria by Hill, A, Richards, S J, Rother, R P, Hillmen, P

“…Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by intravascular hemolysis leading to anemia and other clinical manifestations. Transfusions are…”
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Role of porcine P-selectin in complement-dependent adhesion of human leukocytes to porcine endothelial cells by ROLLINS, S. A, JOHNSON, K. K, LAN LI, BIRKS, C, MATIS, L. A, ROTHER, R. P

“…Rapid leukocyte adherence to donor organ vasculature is a hallmark of hyperacute xenograft rejection. However, the molecular interactions required for…”
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Increasing the specificity of oligo(dT)-primed PCR by Rother, R P

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Porcine vascular cell adhesion molecule (VCAM) mediates endothelial cell adhesion to human T cells. Development of blocking antibodies specific for porcine VCAM by Mueller, J P, Evans, M J, Cofiell, R, Rother, R P, Matis, L A, Elliott, E A

“…Vascular cell adhesion molecule (VCAM) is expressed on activated endothelial cells and binds to the alpha 4 beta 1 integrin receptor, very late antigen-4…”
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Prevention of acute vascular rejection by a functionally blocking anti-C5 monoclonal antibody combined with cyclosporine by HAO WANG, JIFU JIANG, WEIHUA LIU, KUBELIK, Dalibor, GANG CHEN, GIES, David, GARCIA, Bertha, ZHONG, Robert, ROTHER, Russell P

“…Inhibition of the complement cascade at C5 prevents formation of pro-inflammatory molecules C5a and C5b-9, which play a key role in allograft rejection. The…”
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La/SSB ribonucleoprotein levels increased in transformed cells by ROTHER, R. P., THOMAS, P. S.

“…SUMMARY Autoantibodies to the La/SSB ribonucleoprotein are commonly found in patients with Sjögren's syndrome. Previous studies have shown that La/SSB…”
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Inhibition of complement activity by humanized anti-C5 antibody and single-chain Fv by Thomas, Thomas C., Rollins, Scott A., Rother, Russell P., Giannoni, Michelle A., Hartman, Sandra L., Elliott, Eileen A., Nye, Steven H., Matis, Louis A., Squinto, Stephen P., Evans, Mark J.

“…Activation of the complement system contributes significantly to the pathogenesis of numerous acute and chronic diseases. Recently, a monoclonal antibody…”
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Evaluation of the Gal alpha 1-3Gal epitope as a host modification factor eliciting natural humoral immunity to enveloped viruses by Welsh, R M, O'Donnell, CL, Reed, D J, Rother, R P

“…Human sera contain high levels of natural antibody (Ab) to Gal alpha 1-3Gal, a terminal glycosidic structure expressed on the surface of cells of mammals other…”
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The α-Galactosyl Epitope: A Sugar Coating That Makes Viruses and Cells Unpalatable by Rother, Russell P, Squinto, Stephen P

“…Exposure of nonprimate cells, tissues, and organs to human blood typically results in a rapid form of rejection that is mediated by high-titer naturally…”
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alpha-Gal epitopes on viral glycoproteins by Rother, R P, Galili, U

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Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization by HILL, Anita, ROTHER, Russell P, ARNOLD, Louise, KELLY, Richard, CULLEN, Matthew J, RICHARDS, Stephen J, HILLMEN, Peter

“…Paroxysmal nocturnal hemoglobinuria is an acquired hemolytic anemia characterized by intravascular hemolysis which has been demonstrated to be effectively…”
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