Search Results - "Rothenhäusler, Benno"
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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity
Published in Nature communications (03-01-2017)“…The cannabinoid CB 2 receptor (CB 2 R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although…”
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Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis
Published in Molecules (Basel, Switzerland) (13-09-2019)“…(1) Background: The cannabinoid 2 receptor (CB R) is a promising anti-inflammatory drug target and development of selective CB R ligands may be useful for…”
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Surface-plasmon microscopy
Published in Nature (London) (14-04-1988)“…The imaging of low-contrast samples is a challenging task for optical measuring techniques, especially if high lateral resolution is also required. A new…”
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Time domain NMR as a new process monitoring method for characterization of pharmaceutical hydrates
Published in Journal of pharmaceutical and biomedical analysis (15-04-2017)“…•1H time domain NMR (TD-NMR) provides valuable information on molecular water mobility in hydrates.•Methods of spin echo and inversion recovery were suitable…”
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Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases
Published in ChemMedChem (19-01-2016)“…The cannabinoid receptor 2 (CB2) system is described to modulate various pathological conditions, including inflammation and fibrosis. A series of new…”
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NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS
Published in The EMBO journal (15-08-2018)“…Astrocytes are involved in non‐cell‐autonomous pathogenic cascades in amyotrophic lateral sclerosis (ALS); however, their role is still debated. We show that…”
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Process and scaling parameters for wet media milling in early phase drug development: A knowledge based approach
Published in European journal of pharmaceutical sciences (30-03-2018)“…Wet media milling is a well-established unit operation for the manufacturing of suspension formulations during early phase pharmaceutical development. However,…”
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Inside Cover: Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases (ChemMedChem 2/2016)
Published in ChemMedChem (01-01-2016)“…The inside cover picture shows a highly potent and selective triazolopyrimidine‐derived CB2 agonist in the consensus drug‐binding pocket of a CB2 homology…”
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Time Domain 1H NMR as a New Method to Monitor Softening of Gelatin and HPMC Capsule Shells
Published in Drug development and industrial pharmacy (01-11-2006)“…ABSTRACTDefined mechanical properties are an essential requirement for any pharmaceutical dosage form and this is particularly important in the case of…”
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Time Domain 1 H NMR as a New Method to Monitor Softening of Gelatin and HPMC Capsule Shells
Published in Drug development and industrial pharmacy (01-01-2006)Get full text
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Cannabinoid CB 2 receptor ligand profiling reveals biased signalling and off-target activity
Published in Nature communications (03-01-2017)“…The cannabinoid CB receptor (CB R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous…”
Get full text
Journal Article -
12
Total internal diffraction of plasmon surface polaritons
Published in Applied physics letters (14-09-1987)“…Total internal diffraction of plasmon surface polariton fields by a dielectric phase grating is described. The grating was fabricated by partly desorbing thin…”
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Specific Binding of Antigenic Peptides to Separate α and β Chains of Class II Molecules of the Major Histocompatibility Complex
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1990)“…Class II molecules of the major histocompatibility complex bind antigenic peptides and present them to T-helper cells. Class II molecules are heterodimers…”
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Surface plasmon interferometry in the visible
Published in Applied physics letters (09-05-1988)“…Plasmon surface polaritons that are launched at an index step from a Ag/dielectric coating/air to a Ag/air interface interfere with the evanescent waves of the…”
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