Search Results - "Rothenfluh, A"
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Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability
Published in Biomaterials (01-02-2009)“…Abstract The extracellular matrix (ECM) exerts powerful control over many cellular phenomena, including stem cell differentiation. As such, design and…”
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2
Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage
Published in Nature materials (01-03-2008)“…The extracellular matrix of dense, avascular tissues presents a barrier to entry for polymer-based therapeutics, such as drugs encapsulated within polymeric…”
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3
Quantifying the 'law of diminishing returns' in magnetically controlled growing rods
Published in The bone & joint journal (01-12-2017)“…Magnetically controlled growing rods (MCGRs) allow non-invasive correction of the spinal deformity in the treatment of early-onset scoliosis. Conventional…”
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4
Oxford Video Informed Consent Tool (OxVIC): a pilot study of informed video consent in spinal surgery and preoperative patient satisfaction
Published in BMJ open (24-07-2019)“…The British Association of Spinal Surgeons recently called for updates in consenting practice. This study investigates the utility and acceptability of a…”
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5
The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans
Published in Molecular psychiatry (01-03-2018)“…Ubiquitously expressed genes have been implicated in a variety of specific behaviors, including responses to ethanol. However, the mechanisms that confer this…”
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6
Access-related complications in anterior lumbar surgery in patients over 60 years of age
Published in European spine journal (01-04-2014)“…Purpose The anterior approach is widely used for access to the lumbar spine in the setting of adult deformity either as a stand-alone procedure or in combined…”
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7
Evolution of the Cross-Sectional Area of the Osseous Lumbar Spinal Canal across Decades: A CT Study with Reference Ranges in a Swiss Population
Published in Diagnostics (Basel) (01-02-2023)“…Spinal canal dimensions may vary according to ethnicity as reported values differ among studies in European and Chinese populations. Here, we studied the…”
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Pelvic incidence-lumbar lordosis mismatch predisposes to adjacent segment disease after lumbar spinal fusion
Published in European spine journal (01-06-2015)“…Purpose Several risk factors and causes of adjacent segment disease have been debated; however, no quantitative relationship to spino-pelvic parameters has…”
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9
Adult spinal deformity
Published in The Lancet (British edition) (13-07-2019)“…Adult spinal deformity affects the thoracic or thoracolumbar spine throughout the ageing process. Although adolescent spinal deformities taken into adulthood…”
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10
Effectors of alcohol-induced cell killing in Drosophila
Published in Cell death and differentiation (01-10-2012)“…Heavy alcohol consumption provokes an array of degenerative pathologies but the signals that couple alcohol exposure to regulated forms of cell death are…”
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11
Is there an association between the individual anatomy of the scapula and the development of rotator cuff tears or osteoarthritis of the glenohumeral joint?: A radiological study of the critical shoulder angle
Published in The bone & joint journal (01-07-2013)“…We hypothesised that a large acromial cover with an upwardly tilted glenoid fossa would be associated with degenerative rotator cuff tears (RCTs), and…”
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12
Comprehensive assessment of global spinal sagittal alignment and related normal spinal loads in a healthy population
Published in Journal of biomechanics (01-06-2024)“…Abnormal postoperative global sagittal alignment (GSA) is associated with an increased risk of mechanical complications after spinal surgery. Typical…”
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13
Pelvic incidence–lumbar lordosis mismatch results in increased segmental joint loads in the unfused and fused lumbar spine
Published in European spine journal (01-07-2014)“…Purpose Symptomatic adjacent segment disease (ASD) has been reported to occur in up to 27 % of lumbar fusion patients. A previous study identified patients at…”
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14
A critical thoracic kyphosis is required to prevent sagittal plane deterioration in selective thoracic fusions in Lenke I and II AIS
Published in European spine journal (01-12-2019)“…Purpose Thoracic hypokyphosis following AIS correction may be associated with reduced lumbar lordosis with potential adverse effects on the global sagittal…”
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15
Implant and construct decision-making in metastatic spine tumour surgery: a review of current concepts with a decision-making algorithm
Published in European spine journal (01-05-2024)“…Study Design Narrative Review. Objective Metastatic spine tumour surgery (MSTS) is an important treatment modality of metastatic spinal disease (MSD). Increase…”
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16
Findings from a pilot randomized trial of spinal decompression alone or spinal decompression plus instrumented fusion: the Spinal Fusion Indications and Outcomes Randomised Trial (SpInOuT-F) feasibility study
Published in Bone & joint open (08-08-2023)“…Aims Symptomatic spinal stenosis is a very common problem, and decompression surgery has been shown to be superior to nonoperative treatment in selected…”
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17
Is dibotermin alfa a cost-effective substitute for autologous iliac crest bone graft in single level lumbar interbody spine fusion?
Published in Current medical research and opinion (02-11-2015)“…To evaluate the cost-effectiveness of dibotermin alfa compared with autologous iliac crest bone graft (ICBG) for patients undergoing single level lumbar…”
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18
Effect of age on fatty infiltration of supraspinatus muscle after experimental tendon release in rats
Published in BMC research notes (12-12-2011)“…Rotator cuff tendon tear is a leading cause for atrophy, fibrosis and fatty infiltration of the rotator cuff muscles. The pathophysiology of fatty muscle…”
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Treatment of Femoro-Acetabular Impingement: Preliminary Results of Labral Refixation: Surgical Technique
Published in Journal of bone and joint surgery. American volume (01-03-2007)“…BACKGROUND:Recent advances in the understanding of the anatomy and function of the acetabular labrum suggest that it is important for normal joint function. We…”
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20
Intervertebral reaction force prediction using an enhanced assembly of OpenSim models
Published in Computer methods in biomechanics and biomedical engineering (03-04-2016)“…OpenSim offers a valuable approach to investigating otherwise difficult to assess yet important biomechanical parameters such as joint reaction forces…”
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