Search Results - "Roth, R H"

Importance and consumer perception of freshness of apples by Péneau, S., Hoehn, E., Roth, H.-R., Escher, F., Nuessli, J.

“…The present investigation aimed at elucidating the importance of freshness for the consumer and its relationship to sensory and non-sensory properties of…”
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Reduced locomotor responses to cocaine in ghrelin-deficient mice by Abizaid, A, Mineur, Y.S, Roth, R.H, Elsworth, J.D, Sleeman, M.W, Picciotto, M.R, Horvath, T.L

“…Abstract Ghrelin, an orexigenic hormone produced by the stomach, increases food intake and enhances the locomotor and rewarding effects of cocaine. Consistent…”
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The Neuropsychopharmacology of Phencyclidine: From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia by Jentsch, J.David, Roth, Robert H

“…Administration of noncompetitive NMDA/glutamate receptor antagonists, such as phencyclidine (PCP) and ketamine, to humans induces a broad range of…”
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Increased Dopamine Turnover in the Prefrontal Cortex Impairs Spatial Working Memory Performance in Rats and Monkeys by Murphy, B. L., Arnsten, A. F. T., Goldman-Rakic, P. S., Roth, R. H.

“…The selective activation of the prefrontal cortical dopamine system by mild stress can be mimicked by anxiogenic β -carbolines such as FG7142. To investigate…”
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Susceptibility to a parkinsonian toxin varies during primate development by Morrow, B.A., Roth, R.H., Redmond, D.E., Diano, S., Elsworth, J.D.

“…Symptoms of Parkinson's disease typically emerge later in life when loss of nigrostriatal dopamine neuron function exceeds the threshold of compensatory…”
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The role of mesoprefrontal dopamine neurons in the acquisition and expression of conditioned fear in the rat by Morrow, B.A., Elsworth, J.D., Rasmusson, A.M., Roth, R.H.

“…The mesoprefrontal dopamine neurons are sensitive to physical, pharmacological and psychological stressors. In this report, the role of these neurons in the…”
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Spontaneous Blink Rates Correlate with Dopamine Levels in the Caudate Nucleus of MPTP-Treated Monkeys by Taylor, J.R., Elsworth, J.D., Lawrence, M.S., Sladek, J.R., Roth, R.H., Redmond, D.E.

“…Previous studies have suggested a dopaminergic regulation of eye blink rates in human and nonhuman primates. Blockade of either dopamine (DA) D1 or DA D2…”
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Neural stem cells implanted into MPTP-treated monkeys increase the size of endogenous tyrosine hydroxylase-positive cells found in the striatum: a return to control measures by Bjugstad, Kimberly B, Redmond, Jr, D Eugene, Teng, Yang D, Elsworth, J D, Roth, R H, Blanchard, B C, Snyder, Evan Y, Sladek, Jr, John R

“…Neural stem cells (NSC) have been shown to migrate towards damaged areas, produce trophic factors, and replace lost cells in ways that might be therapeutic for…”
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Estrogen Is Essential for Maintaining Nigrostriatal Dopamine Neurons in Primates: Implications for Parkinson's Disease and Memory by Leranth, Csaba, Roth, Robert H, Elsworth, John D, Naftolin, Frederick, Horvath, Tamas L, Redmond, D. Eugene, Jr

“…There are sexual differences in several parameters of the nigrostriatal dopamine neurons, as well as in the progression of diseases associated with this…”
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Phosphorus budget and phosphorus availability in soils under organic and conventional farming by Oehl, F, Oberson, A, HU Tagmann, Besson, J M, Dubois, D, Mäder, P, H-R Roth, Frossard, E

“…The aim of this work was to assess to which extent organic farming practices would affect the accumulation of total and available phosphorus (P) in a cropped…”
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AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons by Elsworth, J.D., Redmond, D.E., Leranth, C., Bjugstad, K.B., Sladek, J.R., Collier, T.J., Foti, S.B., Samulski, R.J., Vives, K.P., Roth, R.H.

“…Neural transplantation offers the potential of treating Parkinson's disease by grafting fetal dopamine neurons to depleted regions of the brain. However,…”
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Subchronic phencyclidine administration reduces mesoprefrontal dopamine utilization and impairs prefrontal cortical-dependent cognition in the rat by Jentsch, J. David, Tran, Anh, Le, Dung, Youngren, Kenneth D., Roth, Robert H.

“…Repeated ingestion of phencyclidine by humans induces enduring schizophrenic symptomatology, particularly cognitive dysfunction. In the presently described…”
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Enduring Cognitive Deficits and Cortical Dopamine Dysfunction in Monkeys After Long-Term Administration of Phencyclidine by Jentsch, J. David, Redmond, D. Eugene, Elsworth, John D., Taylor, Jane R., Youngren, Kenneth D., Roth, Robert H.

“…The effects of the psychotomimetic drug phencyclidine on the neurochemistry and function of the prefrontal cortex in vervet monkeys were investigated. Monkeys…”
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Dopamine Synthesis, Uptake, Metabolism, and Receptors: Relevance to Gene Therapy of Parkinson's Disease by Elsworth, John D., Roth, Robert H.

“…This article gives a brief overview of the current understanding of the life cycle of the dopamine molecule, covering dopamine synthesis, storage, release,…”
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Prenatal cocaine exposure enhances responsivity of locus coeruleus norepinephrine neurons: Role of autoreceptors by Elsworth, J.D, Morrow, B.A, Nguyen, V.-T, Mitra, J, Picciotto, M.R, Roth, R.H

“…Abstract Children exposed to cocaine during gestation have a higher incidence of neurobehavioral deficits. The neurochemical bases of these deficits have not…”
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Embryonic substantia nigra grafts show directional outgrowth to cografted striatal grafts and potential for pathway reconstruction in nonhuman primate by Sladek, Jr, J R, Bjugstad, K B, Collier, T J, Bundock, E A, Blanchard, B C, Elsworth, J D, Roth, R H, Redmond, Jr, D E

“…Transplantation of embryonic dopamine (DA) neurons has been tested as a therapy for Parkinson's disease. Most studies placed DA neurons into the striatum…”
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Altered frontal cortical dopaminergic transmission in monkeys after subchronic phencyclidine exposure: involvement in frontostriatal cognitive deficits by Jentsch, J.D., Taylor, J.R., Elsworth, J.D., Redmond, D.E., Roth, R.H.

“…Long-term exposure to the psychotomimetic drug phencyclidine produces prefrontal cortical cognitive and dopaminergic dysfunction in rats and monkeys, effects…”
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Aged monkeys as a partial model for Parkinson's disease by Hurley, P.J., Elsworth, J.D., Whittaker, M.C., Roth, R.H., Redmond, D.E.

“…Parkinson's Disease (PD) and the natural aging process share a number of biochemical mechanisms, including reduced function of dopaminergic systems. The…”
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5-HT2 Receptor Regulation of Extracellular GABA Levels in the Prefrontal Cortex by Abi-Saab, Walid M., Bubser, Michael, Roth, Robert H., Deutch, Ariel Y.

“…Monoamines, including both dopamine and serotonin, synapse onto prefrontal cortical interneurons. Dopamine has been shown to activate these GABAergic…”
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Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment by ELSWORTH, J. D, TAYLOR, J. R, SLADEK, J. R, COLLIER, T. J, REDMOND, D. E, ROTH, R. H

“…Despite widespread use of the primate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model of Parkinson's disease, there is a paucity of data concerning…”
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