Search Results - "Roth, Michael J."

Quantifying the effects of voluntary contraction and inter-stimulus interval on the human soleus H-reflex by STEIN, Richard B, ESTABROOKS, Kristen L, MCGIE, Steven, ROTH, Michael J, JONES, Kelvin E

“…The human soleus H-reflex is commonly tested as an indicator of the reflex excitability of the calf muscles with infrequent stimuli to a subject seated and at…”
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Implementation of DART and DESI Ionization on a Fieldable Mass Spectrometer by Wells, J. Mitchell, Roth, Michael J., Keil, Adam D., Grossenbacher, John W., Justes, Dina R., Patterson, Garth E., Barket, Dennis J.

“…A recently developed prototype mobile laboratory mass spectrometer, incorporating an atmospheric pressure ionization (API) interface, is described. This system…”
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Precise and Parallel Characterization of Coding Polymorphisms, Alternative Splicing, and Modifications in Human Proteins by Mass Spectrometry by Roth, Michael J, Forbes, Andrew J, Boyne, 2nd, Michael T, Kim, Yong-Bin, Robinson, Dana E, Kelleher, Neil L

“…The human proteome is a highly complex extension of the genome wherein a single gene often produces distinct protein forms due to alternative splicing, RNA…”
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A Lagrangian/semi-Lagrangian coupling approach for accelerated meshfree modelling of extreme deformation problems by Pasetto, Marco, Baek, Jonghyuk, Chen, Jiun-Shyan, Wei, Haoyan, Sherburn, Jesse A., Roth, Michael J.

“…In the reproducing kernel particle method (RKPM), the approximation is achieved through construction of shape functions in the physical domain and the…”
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E-learning Interventions for Quality Improvement Continuing Medical Education-A Scoping Review by Roth, Michael J, Maggio, Lauren A, Costello, Joseph A, Samuel, Anita

“…Improving health care quality and patient safety are top priorities for the medical field. Robust continuing medical education (CME) programs represent major…”
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Parallel Line Sign—A New MRI Sign Associated With Chronic Sacroiliitis: Prevalence, Characteristics, and Associations by Miao, Timothy L., Randhawa, Shubreet, Roth, Michael J., Bureau, Yves, Howey, Joanne, Garvin, Gregory J.

“…Purpose: The purpose is to demonstrate the existence of the parallel line sign (PLS), a dark line parallel to the sacroiliac joint (SIJ), and determine its…”
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Hydrodynamic meshfree method for high-rate solid dynamics using a Rankine-Hugoniot enhancement in a Riemann-SCNI framework by Roth, Michael J., Chen, Jiun-Shyan, Danielson, Kent T., Slawson, Thomas R.

“…Summary Many challenging engineering and scientific problems involve the response of nonlinear solid materials to high‐rate dynamic loading. Accompanying…”
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VISUAL VIGNETTE by Roth, Michael J, Weaver, Travis D, Shakir, Mohamed Km, Hoang, Thanh D

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Modeling finite thickness slab perforation using a coupled Eulerian–Lagrangian approach by Sherburn, Jesse A., Hammons, Michael I., Roth, Michael J.

“…•Penetration experiments were modeled with coupled Eulerian–Lagrangian method.•Constitutive model for concrete was modified and implemented in Abaqus.•A…”
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Stable and flux-conserved meshfree formulation to model shocks by Roth, Michael J., Chen, Jiun-Shyan, Slawson, Thomas R., Danielson, Kent T.

“…Accurate shock modeling requires that two critical issues be addressed: (1) correct representation of the essential shock physics, and (2) control of Gibbs…”
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Top-Down Mass Spectrometry on Tissue Extracts and Biofluids with Isoelectric Focusing and Superficially Porous Silica Liquid Chromatography by Zhang, Junmei, Roth, Michael J, Chang, Audrey N, Plymire, Daniel A, Corbett, John R, Greenberg, Benjamin M, Patrie, Steven M

“…Top-down mass spectrometry (MS) has emerged as a powerful complement to peptide-based proteomics. Despite advancements, the field has had limited application…”
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Top-Down Proteomics on a Chromatographic Time Scale Using Linear Ion Trap Fourier Transform Hybrid Mass Spectrometers by Parks, Bryan A, Jiang, Lihua, Thomas, Paul M, Wenger, Craig D, Roth, Michael J, Boyne, Michael T, Burke, Patricia V, Kwast, Kurt E, Kelleher, Neil L

“…Proteomics has grown significantly with the aid of new technologies that consistently are becoming more streamlined. While processing of proteins from a whole…”
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Sensitive and Reproducible Intact Mass Analysis of Complex Protein Mixtures with Superficially Porous Capillary Reversed-Phase Liquid Chromatography Mass Spectrometry by Roth, Michael J, Plymire, Daniel A, Chang, Audrey N, Kim, Jaekuk, Maresh, Erica M, Larson, Shane E, Patrie, Steven M

“…The compatibility of superficially porous (SP) resin for label-free intact protein analysis with online capillary LC/MS is demonstrated to give improved…”
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Measurement of Blood Protease Kinetic Parameters with Self-Assembled Monolayer Ligand Binding Assays and Label-Free MALDI-TOF MS by Patrie, Steven M, Roth, Michael J, Plymire, Daniel A, Maresh, Erica, Zhang, Junmei

“…We report novel ligand binding assay (LBA) surface modalities that permit plasma protease catalytic efficiency (k cat/k m) determination by MALDI-TOF MS…”
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“Proteotyping”:  Population Proteomics of Human Leukocytes Using Top Down Mass Spectrometry by Roth, Michael J, Parks, Bryan A, Ferguson, Jonathan T, Boyne, Michael T, Kelleher, Neil L

“…Characterizing combinations of coding polymorphisms (cSNPs), alternative splicing and post-translational modifications (PTMs) on a single protein by standard…”
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A MUSCL-SCNI approach for meshfree modeling of shock waves in fluids by Huang, Tsung-Hui, Chen, Jiun-Shyan, Wei, Haoyan, Roth, Michael J., Sherburn, Jesse A., Bishop, Joseph E., Tupek, Michael R., Fang, Eliot H.

“…A stable and nodally integrated meshfree formulation for modeling shock waves in fluids is developed. The reproducing kernel approximation is employed to…”
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Gene-Specific Characterization of Human Histone H2B by Electron Capture Dissociation by Siuti, Nertila, Roth, Michael J, Mizzen, Craig A, Kelleher, Neil L, Pesavento, James J

“…The basis set of protein forms expressed by human cells from the H2B gene family was determined by Top Down Mass Spectrometry. Using Electron Capture…”
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Thin-Layer Matrix Sublimation with Vapor-Sorption Induced Co-Crystallization for Sensitive and Reproducible SAMDI-TOF MS Analysis of Protein Biosensors by Roth, Michael J., Kim, Jaekuk, Maresh, Erica M., Plymire, Daniel A., Corbett, John R., Zhang, Junmei, Patrie, Steven M.

“…Coupling immunoassays on self-assembled monolayers (SAMs) to matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS)…”
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Surface Preparation Strategies for Improved Parallelization and Reproducible MALDI-TOF MS Ligand Binding Assays by Roth, Michael J, Maresh, Erica M, Plymire, Daniel A, Zhang, Junmei, Corbett, John R, Robbins, Roger, Patrie, Steven M

“…Immunoassays are employed in academia and the healthcare and biotech industries for high-throughput, quantitative screens of biomolecules. We have developed…”
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MS-based ligand binding assays with speed, sensitivity, and specificity by Roth, Michael J., Kim, Jaekuk, Maresh, Erica M., Plymire, Daniel A., Corbett, John R., Zhang, Junmei, Patrie, Steven M.

“…Immunoassays are widely used in biochemical/clinical laboratories owing to their simplicity, speed, and sensitivity. We combined self‐assembled monolayer‐based…”
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