Search Results - "Roth, M. D."

Tetraspanins in viral infections : a fundamental role in viral biology? by MARTIN, F, ROTH, D. M, JANS, D. A, POUTON, C. W, PARTRIDGE, L. J, MONK, P. N, MOSELEY, G. W

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Scleroderma lung study (SLS): differences in the presentation and course of patients with limited versus diffuse systemic sclerosis by Clements, Philip J, Roth, Michael D, Elashoff, Robert, Tashkin, Donald P, Goldin, Jonathan, Silver, Richard M, Sterz, Mildred, Seibold, James R, Schraufnagel, Dean, Simms, Robert W, Bolster, Marcy, Wise, Robert A, Steen, Virginia, Mayes, M D, Connelly, Kari, Metersky, Mark, Furst, Daniel E

“…Objectives:Pulmonary fibrosis is a leading cause of death in systemic sclerosis (SSc). This report examines the differences at baseline and over 12 months…”
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Microbial Lipopeptides Stimulate Dendritic Cell Maturation Via Toll-Like Receptor 2 by Hertz, Cheryl J, Kiertscher, Sylvia M, Godowski, Paul J, Bouis, Deborah A, Norgard, Michael V, Roth, Michael D, Modlin, Robert L

“…The ability of dendritic cells (DC) to initiate immune responses in naive T cells is dependent upon a maturation process that allows the cells to develop their…”
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Spatial Multi-omics Reveals the Role of the Wnt Modulator, Dkk2, in Palatogenesis by Piña, J O, Raju, R, Roth, D M, Winchester, E W, Padilla, C, Iben, J, Faucz, F R, Cotney, J L, D'Souza, R N

“…Multiple genetic and environmental etiologies contribute to the pathogenesis of cleft palate, which is the most common of the inherited disorders of the…”
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Activation of Toll-Like Receptor 2 on Human Dendritic Cells Triggers Induction of IL-12, But Not IL-10 by Thoma-Uszynski, Sybille, Kiertscher, Sylvia M, Ochoa, Maria Teresa, Bouis, Deborah A, Norgard, Michael V, Miyake, Kensuke, Godowski, Paul J, Roth, Michael D, Modlin, Robert L

“…Mammalian Toll-like receptors (TLRs) are required for cell activation by bacterial lipoproteins (bLP) and LPS. Stimulation of monocytes with bLP and LPS…”
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Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells by Paquette, Ronald L., Hsu, Nicholas C., Kiertscher, Sylvia M., Park, Alice N., Tran, Lawrence, Roth, Michael D., Glaspy, John A.

“…The diverse roles of interferon‐α (IFN‐α) in regulating the immune response to infectious agents suggested that it might affect dendritic cell (DC)…”
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Vaccination with helper-dependent adenovirus enhances the generation of transgene-specific CTL by HARUI, A, ROTH, M. D, KIERTSCHER, S. M, MITANI, K, BASAK, S. K

“…Recombinant adenoviral vectors (AdV) have been used experimentally as vaccines to present antigenic transgenes in vivo. However, administration of…”
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Histopathologic and Molecular Alterations in Bronchial Epithelium in Habitual Smokers of Marijuana, Cocaine, and/or Tobacco by Barsky, Sanford H., Roth, Michael D., Kleerup, Eric C., Simmons, Michael, Tashkin, Donald P.

“…Background: Tobacco smoking has been observed to cause molecular alterations in bronchial epithelium that antedate the development of lung carcinoma. The…”
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Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy by ROTH, D. M, MEI HUA GAO, CHIN LAI, N, DRUMM, J, DALTON, N, JIN YAO ZHOU, JIAN ZHU, ENTRIKIN, D, HAMMOND, H. K

“…We tested the hypothesis that increased cardiac myocyte adenylyl cyclase (AC) content increases cardiac function and response to catecholamines in…”
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Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice by MEI HUA GAO, CHIN LAI, N, ROTH, D. M, JINYAO ZHOU, JIAN ZHU, ANZAI, T, DALTON, N, HAMMOND, H. K

“…The cellular content of cAMP generated by activation of adenylylcyclase (AC) through the beta-adrenergic receptor (betaAR) is a key determinant of a cell's…”
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Airway Inflammation in Young Marijuana and Tobacco Smokers by ROTH, MICHAEL D, ARORA, ASHIM, BARSKY, SANFORD H, KLEERUP, ERIC C, SIMMONS, MICHAEL, TASHKIN, DONALD P

“…Forty healthy young subjects, ages 20 to 49 yr, underwent videobronchoscopy, mucosal biopsy, and bronchial lavage to evaluate the airway inflammation produced…”
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Human CD14+ leukocytes acquire the phenotype and function of antigen-presenting dendritic cells when cultured in GM-CSF and IL-4 by Kiertscher, Sylvia M., Roth, Michael D.

“…The combination of granulocyte‐macrophage colony stimulating factor (GM‐CSF) and interleukin‐4 (IL‐4) induces the growth of antigen‐presenting cells (APC) from…”
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Induction and regulation of the carcinogen-metabolizing enzyme CYP1A1 by marijuana smoke and delta (9)-tetrahydrocannabinol by Roth, M D, Marques-Magallanes, J A, Yuan, M, Sun, W, Tashkin, D P, Hankinson, O

“…Induction of the carcinogen-metabolizing enzyme cytochrome P4501A1 (CYP1A1) is a key step in the development of tobacco-related cancers. To determine if…”
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Tracheobronchial histopathology in habitual smokers of cocaine, marijuana, and/or tobacco by Fligiel, S E, Roth, M D, Kleerup, E C, Barsky, S H, Simmons, M S, Tashkin, D P

“…Marijuana and alkaloidal cocaine ("crack") are the two most commonly smoked substances in the United States after tobacco. While regular tobacco smoking has…”
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Marijuana and cocaine impair alveolar macrophage function and cytokine production by BALDWIN, G. C, TASHKIN, D. P, BUCKLEY, D. M, PARK, A. N, DUBINETT, S. M, ROTH, M. D

“…Use of marijuana and cocaine is on the rise in the United States. Although pulmonary toxicity from these drugs has occasionally been reported, little is known…”
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Interleukin 2 induces the expression of CD45RO and the memory phenotype by CD45RA+ peripheral blood lymphocytes by ROTH, M. D

“…The CD45RA and CD45RO isoforms of the leukocyte common antigen identify functionally distinct "naive" and "memory" T cell subsets. While antigenic and…”
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Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing by Pfeiffer, E.R, Wright, A.T, Edwards, A.G, Stowe, J.C, McNall, K, Tan, J, Niesman, I, Patel, H.H, Roth, D.M, Omens, J.H, McCulloch, A.D

“…Abstract Mechanical stretch of cardiac muscle modulates action potential propagation velocity, causing potentially arrhythmogenic conduction slowing. The…”
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Presentation of Renal Tumor Antigens by Human Dendritic Cells Activates Tumor-infiltrating Lymphocytes against Autologous Tumor: Implications for Live Kidney Cancer Vaccines by MULDERS, P, TSO, C.-L, BELLDEGRUN, A, GITLITZ, B, KABOO, R, HINKEL, A, FRAND, S, KIERTSCHER, S, ROTH, M. D, DEKERNION, J, FIGLIN, R

“…The clinical impact of dendritic cells (DCs) in the treatment of human cancer depends on their unique role as the most potent antigen-presenting cells that are…”
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Effect of long-term exercise on regional myocardial function and coronary collateral development after gradual coronary artery occlusion in pigs by ROTH, D. M, WHITE, F. C, NICHOLS, M. L, DOBBS, S. L, LONGHURST, J. C, BLOOR, C. M

“…The effect of myocardial ischemia, induced by long-term exercise, on regional myocardial function and coronary collateral development was examined in pigs…”
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Heparin accelerates coronary collateral development in a porcine model of coronary artery occlusion by CARROLL, S. M, WHITE, F. C, ROTH, D. M, BLOOR, C. M

“…Coronary collaterals develop in response to an ischemic stimulus. However, collateral growth is not sufficient to result in the complete recovery of coronary…”
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