Search Results - "Roth, G. S."

Cosmogenic helium and neon in individual chondrules from Allende and Murchison: Implications for the precompaction exposure history of chondrules by ROTH, A. S. G., BAUR, H., HEBER, V. S., REUSSER, E., WIELER, R.

“…– We analyzed cosmogenic He and Ne in more than 60 individual chondrules separated from small chips from the carbonaceous chondrites Allende and Murchison. The…”
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Calorie restriction in nonhuman primates : Effects on diabetes and cardiovascular disease risk by LANE, M. A, INGRAM, D. K, ROTH, G. S

“…The effects of calorie restriction (CR) on life span, disease, and aging in physiological systems have been documented extensively in rodent models. However,…”
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Caloric restriction mimetics: metabolic interventions by Weindruch, R, Keenan, K P, Carney, J M, Fernandes, G, Feuers, R J, Floyd, R A, Halter, J B, Ramsey, J J, Richardson, A, Roth, G S, Spindler, S R

“…Caloric restriction (CR) retards diseases and aging in laboratory rodents and is now being tested in nonhuman primates. One way to apply these findings to…”
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Neon produced by solar cosmic rays in ordinary chondrites by Roth, Antoine S. G, Trappitsch, Reto, Metzler, Knut, Hofmann, Beda A, Leya, Ingo

“…Solar‐cosmic‐ray‐produced Ne (SCR‐Ne), in the form of low cosmogenic 21Ne/22Ne ratios (21Ne/22Necos <0.8), is more likely to be found in rare meteorite…”
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Caloric Restriction in Primates by Lane, M. A., Black, A., Handy, A., Tilmont, E. M., Ingram, D. K., Roth, G. S.

“…: Caloric restriction (CR) remains the only nongenetic intervention that reproducibly extends mean and maximal life span in short‐lived mammalian species. This…”
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Dehydroepiandrosterone sulfate : A biomarker of primate aging slowed by calorie restriction by LANE, M. A, INGRAM, D. K, BALL, S. S, ROTH, G. S

“…The adrenal steroids, dehydroepiandrosterone (DHEA) and its sulfate (DHEAS), have attracted attention for their possible antiaging effects. DHEAS levels in…”
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Calorie Restriction in Primates: Will It Work and How Will We Know? by Roth, George S., Ingram, Donald K., Lane, Mark A.

“…Dietary caloric restriction is the most robust and reproducible means of slowing aging and extending lifespan and healthspan in short‐lived mammals and lower…”
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Cosmic-ray exposure ages of chondrules by Roth, Antoine S. G., Metzler, Knut, Baumgartner, Lukas P., Leya, Ingo

“…If chondrules were exposed to cosmic rays prior to meteorite compaction, they should retain an excess of cosmogenic noble gases. Beyersdorf‐Kuis et al. (2015)…”
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Energy restriction does not alter bone mineral metabolism or reproductive cycling and hormones in female rhesus monkeys by Lane, M A, Black, A, Handy, A M, Shapses, S A, Tilmont, E M, Kiefer, T L, Ingram, D K, Roth, G S

“…Energy restriction (ER) extends the life span and slows aging and age-related diseases in short-lived mammalian species. Although a wide variety of…”
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Activity measures in rhesus monkeys on long-term calorie restriction by WEED, J. L, LANE, M. A, ROTH, G. S, SPEER, D. L, INGRAM, D. K

“…Calorie restriction (CR), undernutrition without malnutrition, extends the mean and maximal lifespan of several ecologically diverse species. Rodents on CR…”
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Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents by Lane, M.A. (Hopkins Bayview Medical Center, Baltimore, MD.), Baer, D.J, Rumpler, W.V, Weindruch, R, Ingram, D.K, Tilmont, E.M, Cutler, R.G, Roth, G.S

“…Many studies of caloric restriction (CR) in rodents and lower animals indicate that this nutritional manipulation retards aging processes, as evidenced by…”
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Effects of reduced energy intake on the biology of aging: the primate model by Roth, G S, Ingram, D K, Black, A, Lane, M A

“…Dietary energy restriction is the only proven method for extending lifespan and slowing aging in mammals, while maintaining health and vitality. Although the…”
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Effect of Caloric Restriction on the 24-Hour Plasma DHEAS and Cortisol Profiles of Young and Old Male Rhesus Macaques by URBANSKI, H F., DOWNS, J L, GARYFALLOU, V T, MATTISON, J A, LANE, M A, ROTH, G S, INGRAM, D K

“…: Although dietary caloric restriction (CR) can retard aging in laboratory rats and mice, it is unclear whether CR can exert similar effects in long‐lived…”
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Amyloid β -Peptide Disrupts Carbachol-Induced Muscarinic Cholinergic Signal Transduction in Cortical Neurons by Kelly, Jeremiah F., Furukawa, Katsutoshi, Barger, Steven W., Rengen, Mohan R., Mark, Robert J., Blanc, Emmanuelle M., Roth, George S., Mattson, Mark P.

“…Cholinergic pathways serve important functions in learning and memory processes, and deficits in cholinergic transmission occur in Alzheimer disease (AD). A…”
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Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory end points by Lane, M.A. (Hopkins Bayview Medical Center, Baltimore, MD.), Ball, S.S, Ingram, D.K, Cutler, R.G, Engel, J, Read, V, Roth, G.S

“…Male rhesus monkeys (Macaca mulatta) of different age groups representing the species life span were fed ad libitum or a 30% reduced calorie diet over a 7-yr…”
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Age-related decline in striatal volume in monkeys as measured by magnetic resonance imaging by Matochik, J.A, Chefer, S.I, Lane, M.A, Woolf, R.I, Morris, E.D, Ingram, D.K, Roth, G.S, London, E.D

“…Age-related declines in striatal markers for the dopamine system have been demonstrated in several species. The current study investigated structural changes…”
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A nonhuman primate model of age-related bone loss: a longitudinal study in male and premenopausal female rhesus monkeys by Black, A, Tilmont, E.M, Handy, A.M, Scott, W.W, Shapses, S.A, Ingram, D.K, Roth, G.S, Lane, M.A

“…Aging is associated with gradual bone loss in men and premenopausal women, with an accelerated rate of loss after menopause in women. Although many studies…”
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Longevity and the Genetic Determination of Collagen Glycoxidation Kinetics in Mammalian Senescence by Sell, David R., Lane, Mark A., Johnson, Wesley A., Masoro, Edward J., Mock, Orin B., Reiser, Karen M., Fogarty, John F., Cutler, Richard G., Ingram, Donald K., Roth, George S., Monnier, Vincent M.

“…A fundamental question in the basic biology of aging is whether there is a universal aging process. If indeed such a process exists, one would expect that it…”
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Physiological levels of β-amyloid peptide promote PC12 cell proliferation by Luo, Y., Sunderland, T., Roth, G.S., Wolozin, B.

“…Alzheimer's β-amyloid peptide (Aβ) is normally present at a subnanomolar (225–625 pM) concentration in body fluids and in the medium of cultured cells. The…”
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Promotion of Wound Repair in Old Mice by Local Injection of Macrophages by Danon, David, Kowatch, Mary Ann, Roth, George S.

“…Application of peritoneal macrophages to experimentally induced cutaneous wounds of old mice accelerates healing to levels almost comparable to those of…”
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