Search Results - "Roth, C.E."

The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines by Levin, J.I, Chen, J.M, Du, M.T, Nelson, F.C, Wehr, T, DiJoseph, J.F, Killar, L.M, Skala, S, Sung, A, Sharr, M.A, Roth, C.E, Jin, G, Cowling, R, Di, L, Sherman, M, Xu, Z.B, March, C.J, Mohler, K.M, Black, R.A, Skotnicki, J.S

“…Anthranilic acid derivatives bearing basic amines were prepared and evaluated in vitro and in vivo as inhibitors of MMP-1, MMP-9, MMP-13, and TACE. Piperazine…”
Get full text

Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors by Zask, A., Gu, Y., Albright, J.D., Du, X., Hogan, M., Levin, J.I., Chen, J.M., Killar, L.M., Sung, A., DiJoseph, J.F., Sharr, M.A., Roth, C.E., Skala, S., Jin, G., Cowling, R., Mohler, K.M., Barone, D., Black, R., March, C., Skotnicki, J.S.

“…Potent and selective bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors were synthesized by a novel convergent route. Selectivity and efficacy versus…”
Get full text

Investigation into a cluster of infant deaths following immunization: evidence for methanol intoxication by Darwish, A, Roth, C.E, Duclos, P, Ohn, S.A, Nassar, A, Mahoney, F, Vogt, R, Arthur, R.R

“…A cluster of infant deaths due to severe metabolic acidosis following immunization was reported in a prosperous farming village in Egypt. Fears that more…”
Get full text

Performance of a compact, cascade FCG system by Parker, J.V., Roth, C.E., Coffey, S.K., Lehr, F.M., Degnan, J.H.

“…A system of two FCG's coupled via ¿flux-trapping¿ is described. The driver FCG, designated SAM, was custom-designed for this application. The output of SAM is…”
Get full text

Development and Testing of a High-Gain Magnetic Flux Compression Generator by Parker, J.V., Cavazos, T.C., Roth, C.E., Degnan, J.H., Kiuttu, G.F., Lehr, F.M.

“…The performance of a high-gain FCG is often limited by internal electrical breakdown caused by the high voltage generated during operation. Modern diagnostic…”
Get full text

A Ceramic Loaded Polymer Blumlein Pulser for Compact, Rep-Rated Pulsed Power Applications by Domonkos, M.T., Turchi, P.J., Parker, J.V., Grabowski, T.C., Gregg, C.W., Roth, C.E., Slenes, K.

“…The design of compact pulsed power systems involves the trade between size, pulse length and pulse shape. A stacked Blumlein line with high dielectric constant…”
Get full text

Flux Compression Generator Development at the Air Force Research Laboratory by Cavazos, T.C., Gale, D.G., Roth, C.E., Parker, J.V., Sommars, W.E., Coffey, S.K., Lehr, F.M., Tucker, W.D., Kiuttu, G.F., Degnan, J.H.

“…The Air Force Research Laboratory (AFRL) maintains an extensive capability for the design, analysis, construction and testing of explosive pulsed power (EPP)…”
Get full text

The Explosive Pulsed Power Test Facility at AFRL by Parker, J.V., Cavazos, T.C., Roth, C.E., Sandoval, D.R., Sommars, W., Lehr, F.M., Kiuttu, G.F., Chama, D., Degnan, J.H., Coffey, S., Brown, A., Guffey, B.

“…The Air Force Research Laboratory has developed and tested a variety of explosive driven pulsed power devices over the past twenty-two years. Testing is…”
Get full text