Search Results - "Roth, B.L"

Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex by Nocjar, C, Alex, K.D, Sonneborn, A, Abbas, A.I, Roth, B.L, Pehek, E.A

“…Highlights • Most GABA cells in layer V of the rat prelimbic mPFC expressed 5-HT2C receptors. • Likewise, most 5-HT2C receptor-expressing cells were GABAergic…”
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Localization of 5-HT2A receptors on dopamine cells in subnuclei of the midbrain A10 cell group by NOCJAR, C, ROTH, B. L, PEHEK, E. A

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Selective manipulation of spinal microglia by chemogenetics: Implications for allodynia and inflammatory signaling by Grace, P.M, Wang, X, Urban, D.J, Baratta, M.V, Galer, E.L, Strand, K.A, Zhang, Y, Yin, H, Roth, B.L, Maier, S.F, Watkins, L.R

“…The absence of selective pharmacological tools is a major barrier to the in vivo study of microglia. To address this issue, we developed a Gq- and Gi-coupled…”
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P.1.h.029 MK-801-induced hyperlocomotion in rats is affected by modulation of α5 -containing GABAA receptors by Timic, T, Joksimovic, S, Obradovic, A.L, Poe, M.M, Biawat, P, Ramerstorfer, J, Roth, B.L, Sieghart, W, Cook, J.M, Savic, M.M

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Similar ultrastructural distribution of the 5-HT2A serotonin receptor and microtubule-associated protein MAP1A in cortical dendrites of adult rat by CORNEA-HEBERT, V, WATKINS, K. C, ROTH, B. L, KROEZE, W. K, GAUDREAU, P, LECLERC, N, DESCARRIES, L

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P.1.c.044 SH-I-048A, a novel positive modulator of GABA-A receptor: in vitro and behavioral profile by Joksimovic, S.M, Huang, S, Ramerstorfer, J, Milinkovic, M.M, Divljakovic, J.M, Roth, B.L, Sieghart, W, Savic, M.M, Cook, J.M

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Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors by PULLAGURLA, Manik, SIRIPURAPU, Uma, KOLANOS, Renata, BONDAREV, Mikhail L, DUKAT, Małgorzata, SETOLA, V, ROTH, B. L, GLENNON, Richard A

“…An examination of several amine-substituted analogs of N(1)-benzenesulfonylindoles reveals that although they bind at human 5-HT(6) serotonin receptors with…”
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P.1.d.016 Jy-xhe-053, a benzodiazepine ligand less efficacious at GABAA receptors containing alphal and alpha5 than alpha2 and alpha3 subunits by Milinkovic, M.M, Savic, M.M, Huang, S, Furtmüller, R, Majumder, S, Samardic, J, Divljakovic, J.M, Roth, B.L, Sieghart, W, Cook, J.M

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P.1.d.018 WYS-8, a novel ligand at GABAA receptors: a step forward to linking in vitro with in vivo selectivity? by Joksimovic, S.M, Savic, M.M, Milinkovic, M.M, Van Linn, M, Ramerstorfer, J, Majumder, S, Yin, W, Roth, B.L, Sieghart, W, Cook, J.M

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PRESTO-TANGO: an open-source resource for interrogation of the druggable human GPCR-ome by Kroeze, W.K., Sassano, M.F., Huang, X.-P., Lansu, K., McCorvy, J.D., Giguere, P.M., Sciaky, N., Roth, B.L.

“…G protein-coupled receptors (GPCRs) are essential mediators of cellular signaling and important targets of drug action. Of the approximately 350 non-olfactory…”
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Thermal structure and tectonic evolution of the Scandian orogenic wedge, Scottish Caledonides: integrating geothermometry, deformation temperatures and conceptual kinematic-thermal models by Thigpen, J.R., Law, R.D., Loehn, C.L., Strachan, R. A., Tracy, R.J., Lloyd, G.E., Roth, B.L., Brown, S.J.

“…In the Caledonides of northwest Scotland, two independent geothermometers (Fe‐Mg exchange and quartz c‐axis fabric opening angle) are used to characterize the…”
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Inhibition of medio-dorsal thalamus disrupts thalamo-frontal connectivity and cognition by Parnaudeau, S., O'Neill, P.K., Bolkan, S., Ward, R.D., Abbas, A.I., Roth, B.L., Balsam, P., Gordon, J.A., Kellendonk, C.

“…Cognitive deficits are central to schizophrenia but the underlying mechanisms still remain unclear. Imaging studies performed in patients point to decreased…”
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Thermal structure and tectonic evolution of the Scandian orogenic wedge, S cottish Caledonides: integrating geothermometry, deformation temperatures and conceptual kinematic‐thermal models by Thigpen, J.R., Law, R.D., Loehn, C.L., Strachan, R. A., Tracy, R.J., Lloyd, G.E., Roth, B.L., Brown, S.J.

“…Abstract In the Caledonides of northwest Scotland, two independent geothermometers (Fe‐Mg exchange and quartz c‐axis fabric opening angle) are used to…”
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The PDZ-binding domain is essential for the dendritic targeting of 5-HT2A serotonin receptors in cortical pyramidal neurons in vitro by XIA, Z, HUFEISEN, S. J, GRAY, J. A, ROTH, B. L

“…The 5-HT(2A) serotonin receptor represents an important molecular target for atypical antipsychotic drugs and for most hallucinogens. In the mammalian cerebral…”
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Development of the FUN-1 family of fluorescent probes for vacuole labeling and viability testing of yeasts by Millar, P.J. (Molecular Probes, Inc., Eugene, OR.), Roth, B.L, Thi, H.P.T, Yue, S.T, Haugland, R.P

“…A new family of fluorescent probes has been developed for assessing the viability and metabolic activity of yeasts. This class of halogenated unsymmetric…”
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Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo by Willins, D.L., Berry, S.A., Alsayegh, L., Backstrom, J.R., Sanders-Bush, E., Friedman, L., Roth, B.L.

“…In this study, we demonstrate that clozapine and other atypical antipsychotic drugs induce a paradoxical internalization of 5-hydroxytryptamine-2A receptors in…”
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Localization of 5-HT 2A receptors on dopamine cells in subnuclei of the midbrain A10 cell group by Nocjar, C, Roth, B.L, Pehek, E.A

“…Considerable evidence suggests that a dysfunction of the dopamine and serotonin (5-hydroxytryptamine or 5-HT) neurotransmitter systems contributes to a diverse…”
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19. Clozapine alters the subcellular distribution of 5-HT2A receptors by Roth, B.L., Willins, D.L.

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431. Clozapine-induced internalization of the 5-HT2A receptor in vitro by Berry, S.A., Roth, B.L.

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431. Clozapine-induced internalization of the 5-HT 2A receptor in vitro by Berry, S.A., Roth, B.L.

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