Search Results - "Rote, Neal S."

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses by Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Buhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner

“…We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in cancer through the viral defense pathway. In ovarian cancer (OC), DNMTis…”
Get full text

Progesterone Receptor-A and -B Have Opposite Effects on Proinflammatory Gene Expression in Human Myometrial Cells: Implications for Progesterone Actions in Human Pregnancy and Parturition by Tan, Huiqing, Yi, Lijuan, Rote, Neal S, Hurd, William W, Mesiano, Sam

“…Context: Progesterone promotes uterine relaxation during pregnancy and its withdrawal induces labor. Progesterone withdrawal in human parturition is mediated…”
Get full text

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses by Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Budhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner

Get full text

Evidence of proatherogenic inflammation in polycystic ovary syndrome by González, Frank, Rote, Neal S, Minium, Judi, Kirwan, John P

“…Abstract Women with polycystic ovary syndrome (PCOS) have chronic low-level inflammation that can increase the risk of atherogenesis. We measured circulating…”
Get full text

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses by Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Budhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner

Get full text

Reactive Oxygen Species-Induced Oxidative Stress in the Development of Insulin Resistance and Hyperandrogenism in Polycystic Ovary Syndrome by González, Frank, Rote, Neal S., Minium, Judi, Kirwan, John P.

“…Context: Insulin resistance and chronic low level inflammation are often present in women with polycystic ovary syndrome (PCOS). Objective: The purpose of this…”
Get full text

Evidence of mononuclear cell preactivation in the fasting state in polycystic ovary syndrome by González, Frank, MD, Kirwan, John P., PhD, Rote, Neal S., PhD, Minium, Judi, BS

“…Objective We evaluated mononuclear cell (MNC) preactivation in women with polycystic ovary syndrome (PCOS) by examining the effect of in vitro…”
Get full text

Elevated circulating levels of macrophage migration inhibitory factor in polycystic ovary syndrome by González, Frank, Rote, Neal S., Minium, Judi, Weaver, Amy L., Kirwan, John P.

“…Women with polycystic ovary syndrome (PCOS) have chronic low level inflammation which can increase the risk of atherogenesis. We evaluated the status of…”
Get full text

The Altered Mononuclear Cell-Derived Cytokine Response to Glucose Ingestion Is Not Regulated by Excess Adiposity in Polycystic Ovary Syndrome by González, Frank, Sia, Chang Ling, Shepard, Marguerite K, Rote, Neal S, Minium, Judi

“…Context: Excess adipose tissue is a source of inflammation. Polycystic ovary syndrome (PCOS) is a proinflammatory state and is often associated with excess…”
Get full text

Inflammation in Response to Glucose Ingestion Is Independent of Excess Abdominal Adiposity in Normal-Weight Women with Polycystic Ovary Syndrome by González, Frank, Sia, Chang Ling, Shepard, Marguerite K, Rote, Neal S, Minium, Judi

“…Context: Inflammation and excess abdominal adiposity (AA) are often present in normal-weight women with polycystic ovary syndrome (PCOS). Objective: We…”
Get full text

Increased Activation of Nuclear Factor κB Triggers Inflammation and Insulin Resistance in Polycystic Ovary Syndrome by González, Frank, Rote, Neal S., Minium, Judi, Kirwan, John P.

“…Context: Insulin resistance and chronic low level inflammation are often present in women with polycystic ovary syndrome (PCOS). Objective: The purpose of this…”
Get full text

Hyperglycemia-induced oxidative stress is independent of excess abdominal adiposity in normal-weight women with polycystic ovary syndrome by González, Frank, Sia, Chang Ling, Shepard, Marguerite K., Rote, Neal S., Minium, Judi

“…STUDY QUESTION What is the effect of glucose ingestion on leukocytic reactive oxygen species (ROS) generation in normal-weight women with polycystic ovary…”
Get full text

Glucose ingestion stimulates atherothrombotic inflammation in polycystic ovary syndrome by González, Frank, Kirwan, John P, Rote, Neal S, Minium, Judi

“…Women with polycystic ovary syndrome (PCOS) have chronic low-grade inflammation that can increase the risk of atherothrombosis. We performed a cross-sectional…”
Get more information

Hyperglycemia Alters Tumor Necrosis Factor-α Release from Mononuclear Cells in Women with Polycystic Ovary Syndrome by González, Frank, Minium, Judi, Rote, Neal S., Kirwan, John P.

“…Context: Women with polycystic ovary syndrome (PCOS) are often insulin resistant and have chronic low-level inflammation. Objective: The purpose of this study…”
Get full text

Elevated circulating levels of tissue factor in polycystic ovary syndrome by González, Frank, Kirwan, John P, Rote, Neal S, Minium, Judi

“…Women with polycystic ovary syndrome (PCOS) have coagulation disturbances and inflammation, which increases the risk of atherothrombosis. We evaluated the…”
Get more information

Glucose and lipopolysaccharide regulate proatherogenic cytokine release from mononuclear cells in polycystic ovary syndrome by González, Frank, Kirwan, John P, Rote, Neal S, Minium, Judi, O’Leary, Valerie B

“…Abstract Women with polycystic ovary syndrome (PCOS) have chronic low-grade inflammation, which can increase the risk of atherogenesis. We examined the effect…”
Get full text

Decreased expression of P2X7 in endometrial epithelial pre-cancerous and cancer cells by Li, Xin, Qi, Xiaoping, Zhou, Lingyin, Catera, Deborah, Rote, Neal S, Potashkin, Judith, Abdul-Karim, Fadi W, Gorodeski, George I

“…Abstract Objectives To understand the potential role of P2X7 as biomarker of endometrial cancer, and the molecular mechanisms by which cancerous epithelial…”
Get full text

Obese Reproductive-Age Women Exhibit a Proatherogenic Inflammatory Response During Hyperglycemia by González, Frank, Rote, Neal S., Minium, Judi, O'Leary, Valerie B., Kirwan, John P.

“…Objective: The objective was to determine if physiological hyperglycemia induces a proatherogenic inflammatory response in mononuclear cells (MNCs) in obese…”
Get full text

Altered tumor necrosis factor α release from mononuclear cells of obese reproductive-age women during hyperglycemia by González, Frank, Minium, Judi, Rote, Neal S., Kirwan, John P.

“…The aim of the study was to determine whether lipopolysaccharide (LPS)-stimulated tumor necrosis factor α (TNF- α) release from mononuclear cells (MNCs) is…”
Get full text

Expression of phosphatidylserine-dependent antigens on the surface of differentiating BeWo human choriocarcinoma cells by Rote, N S, Chang, J, Katsuragawa, H, Ng, A K, Lyden, T W, Mori, T

“…Antiphospholipid antibodies (aPLs) are associated with pregnancy loss, pregnancy-induced hypertension, and intrauterine growth retardation. We have previously…”
Get more information