Search Results - "Rota Nodari, Laura"
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Mild hypoxia enhances proliferation and multipotency of human neural stem cells
Published in PloS one (05-01-2010)“…Neural stem cells (NSCs) represent an optimal tool for studies and therapy of neurodegenerative diseases. We recently established a v-myc immortalized human…”
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Transplantation of clinical-grade human neural stem cells reduces neuroinflammation, prolongs survival and delays disease progression in the SOD1 rats
Published in Cell death & disease (25-04-2019)“…Stem cells are emerging as a therapeutic option for incurable diseases, such as Amyotrophic Lateral Sclerosis (ALS). However, critical issues are related to…”
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Long-term survival of human neural stem cells in the ischemic rat brain upon transient immunosuppression
Published in PloS one (19-11-2010)“…Understanding the physiology of human neural stem cells (hNSCs) in the context of cell therapy for neurodegenerative disorders is of paramount importance, yet…”
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Immortalization of human neural stem cells with the c-myc mutant T58A
Published in PloS one (02-10-2008)“…Human neural stem cells (hNSC) represent an essential source of renewable brain cells for both experimental studies and cell replacement therapies. Their…”
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Histopathology of Clinical Coronary Restenosis in Drug-Eluting Versus Bare Metal Stents
Published in The American journal of cardiology (15-12-2009)“…To characterize in-stent restenosis after the implantation of sirolimus-eluting stents (SES), paclitaxel-eluting stents (PES), tacrolimus-eluting stents (TES),…”
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Human neural stem cell transplantation in ALS: initial results from a phase I trial
Published in Journal of translational medicine (27-01-2015)“…We report the initial results from a phase I clinical trial for ALS. We transplanted GMP-grade, fetal human neural stem cells from natural in utero death…”
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Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model
Published in Cellular and molecular life sciences : CMLS (01-04-2012)“…Cell therapy is reaching the stage of phase I clinical trials for post-traumatic, post-ischemic, or neurodegenerative disorders, and the selection of the…”
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Storage of Mutant Human SOD1 in Non-Neural Cells from the Type-1 Amyotrophic Lateral Sclerosis ratG93A Model Correlated with the Lysosomes’ Dysfunction
Published in Biomedicines (24-08-2021)“…Herein, we explored the impact of the lysosome dysfunction during the progression of Amyotrophic Lateral Sclerosis type-1 (ALS1). We conducted the study in…”
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