Search Results - "Roszak, A W"
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High-Throughput Screens for Postgenomics: Studies of Protein Crystallization Using Microsystems Technology
Published in Analytical chemistry (Washington) (15-07-2002)“…This paper describes the fabrication of a micromachined miniaturized array of chambers in a 2-mm-thick single crystal 〈100〉 silicon substrate for the…”
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Experiences with the shikimate-pathway enzymes as targets for rational drug design
Published in Biochemical Society transactions (01-06-2003)“…The background and current context of work on the shikimate-pathway enzymes as potential targets for anti-bacterial, anti-fungal and anti-parasitic drugs is…”
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Crystal Structure of the RC-LH1 Core Complex from Rhodopseudomonas palustris
Published in Science (American Association for the Advancement of Science) (12-12-2003)“…The crystal structure at 4.8 angstrom resolution of the reaction center-light harvesting 1 (RC-LH1) core complex from Rhodopseudomonas palustris shows the…”
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Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities
Published in The Journal of biological chemistry (23-05-2003)“…Shikimate dehydrogenase catalyzes the fourth step of the shikimate pathway, the essential route for the biosynthesis of aromatic compounds in plants and…”
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Rings, ellipses and horseshoes: how purple bacteria harvest solar energy
Published in Photosynthesis research (01-01-2004)“…This Review summarises the current state of research on the structure and function of light-harvesting apparatus in purple photosynthetic bacteria. Particular…”
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5,5-Diphenyl-2-thiohydantoin
Published in Acta crystallographica. Section C, Crystal structure communications (15-08-1998)Get full text
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Probing the interface between membrane proteins and membrane lipids by X-ray crystallography
Published in Trends in Biochemical Sciences (01-02-2001)“…Biological membranes are composed of a complex mixture of lipids and proteins, and the membrane lipids support several key biophysical functions, in addition…”
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Book Review Journal Article -
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Structure of 5 beta-dihydrotestosterone
Published in Acta crystallographica. Section C, Crystal structure communications (15-09-1990)“…17 beta-Hydroxy-5 beta-androstan-3-one, C19H30O2, Mr = 290.45, orthorhombic, P2(1)2(1)2(1), a = 11.7821 (6), b = 21.2184 (8), c = 6.5322 (2) A, V = 1633.0 (2)…”
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Structural studies of thiophilic N-chloroazasteroids
Published in Acta crystallographica. Section B, Structural science (01-06-1991)“…N-Chloroazasteroids form covalent S-N bonds with thiol groups and so are of interest as chemoselective irreversible binding agents for the active sites of…”
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3-Deoxy-d-fructose
Published in Acta crystallographica. Section C, Crystal structure communications (15-12-1997)Get full text
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Structural requirements for the binding of dexamethasone to nuclear envelopes and plasma membranes
Published in The Journal of steroid biochemistry and molecular biology (01-10-1990)“…The specificity of dexamethasone binding sites on nuclear envelopes (NE) and plasma membranes (PM) was determined in competition studies with natural and…”
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Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 Å resolution
Published in Acta crystallographica. Section D, Biological crystallography. (01-01-1999)“…The three‐dimensional structure of the R form of rabbit liver fructose 1,6‐bisphosphatase (Fru‐1,6‐Pase; E.C. 3.1.3.11) has been determined by a combination of…”
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Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides
Published in Structure (London) (01-05-2004)“…X-ray diffraction was used to determine high-resolution structures of the reaction center (RC) complex from the carotenoidless mutant, Rb. sphaeroides R-26.1,…”
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Bovine Mitochondrial Peroxiredoxin III Forms a Two-Ring Catenane
Published in Structure (London) (01-11-2005)“…A crystal structure is reported for the C168S mutant of a typical 2-Cys peroxiredoxin III (Prx III) from bovine mitochondria at a resolution of 3.3 Å. Prx III…”
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Brominated Lipids Identify Lipid Binding Sites on the Surface of the Reaction Center from Rhodobacter sphaeroides
Published in Biochemistry (Easton) (20-03-2007)“…This study describes the use of brominated phospholipids to distinguish between lipid and detergent binding sites on the surface of a typical α-helical…”
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Crystallization of purple bacterial LH2 antenna complexes
Published in Acta crystallographica. Section A, Foundations of crystallography (22-08-2007)“…Abstract only…”
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The Structure and Mechanism of the Type II Dehydroquinase from Streptomyces coelicolor
Published in Structure (London) (01-04-2002)“…The structure of the type II DHQase from Streptomyces coelicolor has been solved and refined to high resolution in complexes with a number of ligands,…”
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Interactions of phospholipids with integral membrane proteins; use of brominated lipids
Published in Acta crystallographica. Section A, Foundations of crystallography (23-08-2005)“…Abstract only…”
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