Search Results - "Roszak, A W"

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    High-Throughput Screens for Postgenomics:  Studies of Protein Crystallization Using Microsystems Technology by Juárez-Martínez, G, Steinmann, P, Roszak, A. W, Isaacs, N. W, Cooper, J. M

    Published in Analytical chemistry (Washington) (15-07-2002)
    “…This paper describes the fabrication of a micromachined miniaturized array of chambers in a 2-mm-thick single crystal 〈100〉 silicon substrate for the…”
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    Journal Article
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    Experiences with the shikimate-pathway enzymes as targets for rational drug design by Coggins, J R, Abell, C, Evans, L B, Frederickson, M, Robinson, D A, Roszak, A W, Lapthorn, A P

    Published in Biochemical Society transactions (01-06-2003)
    “…The background and current context of work on the shikimate-pathway enzymes as potential targets for anti-bacterial, anti-fungal and anti-parasitic drugs is…”
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    Journal Article
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    Crystal Structure of the RC-LH1 Core Complex from Rhodopseudomonas palustris by Roszak, Aleksander W., Howard, Tina D., Southall, June, Gardiner, Alastair T., Law, Christopher J., Isaacs, Neil W., Cogdell, Richard J.

    “…The crystal structure at 4.8 angstrom resolution of the reaction center-light harvesting 1 (RC-LH1) core complex from Rhodopseudomonas palustris shows the…”
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    Journal Article
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    Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities by Michel, Gurvan, Roszak, Aleksander W, Sauvé, Véronique, Maclean, John, Matte, Allan, Coggins, John R, Cygler, Miroslaw, Lapthorn, Adrian J

    Published in The Journal of biological chemistry (23-05-2003)
    “…Shikimate dehydrogenase catalyzes the fourth step of the shikimate pathway, the essential route for the biosynthesis of aromatic compounds in plants and…”
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    Rings, ellipses and horseshoes: how purple bacteria harvest solar energy by Cogdell, Richard J, Gardiner, Alastair T, Roszak, Aleksander W, Law, Christopher J, Southall, June, Isaacs, Neil W

    Published in Photosynthesis research (01-01-2004)
    “…This Review summarises the current state of research on the structure and function of light-harvesting apparatus in purple photosynthetic bacteria. Particular…”
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    Journal Article
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    Probing the interface between membrane proteins and membrane lipids by X-ray crystallography by Fyfe, Paul K, McAuley, Katherine E, Roszak, Aleksander W, Isaacs, Neil W, Cogdell, Richard J, Jones, Michael R

    Published in Trends in Biochemical Sciences (01-02-2001)
    “…Biological membranes are composed of a complex mixture of lipids and proteins, and the membrane lipids support several key biophysical functions, in addition…”
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    Book Review Journal Article
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    Structure of 5 beta-dihydrotestosterone by Roszak, A W, Codding, P W

    “…17 beta-Hydroxy-5 beta-androstan-3-one, C19H30O2, Mr = 290.45, orthorhombic, P2(1)2(1)2(1), a = 11.7821 (6), b = 21.2184 (8), c = 6.5322 (2) A, V = 1633.0 (2)…”
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    Structural studies of thiophilic N-chloroazasteroids by Roszak, A W, Brunner, K, Back, T G, Codding, P W

    “…N-Chloroazasteroids form covalent S-N bonds with thiol groups and so are of interest as chemoselective irreversible binding agents for the active sites of…”
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    Structural requirements for the binding of dexamethasone to nuclear envelopes and plasma membranes by Roszak, A W, Lefebvre, Y A, Howell, G M, Codding, P W

    “…The specificity of dexamethasone binding sites on nuclear envelopes (NE) and plasma membranes (PM) was determined in competition studies with natural and…”
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    Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 Å resolution by Weeks, Charles M., Roszak, Aleksander W., Erman, Mary, Kaiser, Rudolf, Jörnvall, Hans, Ghosh, Debashis

    “…The three‐dimensional structure of the R form of rabbit liver fructose 1,6‐bisphosphatase (Fru‐1,6‐Pase; E.C. 3.1.3.11) has been determined by a combination of…”
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    Journal Article
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    Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides by Roszak, Aleksander W, McKendrick, Kimberley, Gardiner, Alastair T, Mitchell, Iain A, Isaacs, Neil W, Cogdell, Richard J, Hashimoto, Hideki, Frank, Harry A

    Published in Structure (London) (01-05-2004)
    “…X-ray diffraction was used to determine high-resolution structures of the reaction center (RC) complex from the carotenoidless mutant, Rb. sphaeroides R-26.1,…”
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    Journal Article
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    Bovine Mitochondrial Peroxiredoxin III Forms a Two-Ring Catenane by Cao, Zhenbo, Roszak, Aleksander W., Gourlay, Louise J., Lindsay, J. Gordon, Isaacs, Neil W.

    Published in Structure (London) (01-11-2005)
    “…A crystal structure is reported for the C168S mutant of a typical 2-Cys peroxiredoxin III (Prx III) from bovine mitochondria at a resolution of 3.3 Å. Prx III…”
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    Brominated Lipids Identify Lipid Binding Sites on the Surface of the Reaction Center from Rhodobacter sphaeroides by Roszak, Aleksander W, Gardiner, Alastair T, Isaacs, Neil W, Cogdell, Richard J

    Published in Biochemistry (Easton) (20-03-2007)
    “…This study describes the use of brominated phospholipids to distinguish between lipid and detergent binding sites on the surface of a typical α-helical…”
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    Journal Article
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    The Structure and Mechanism of the Type II Dehydroquinase from Streptomyces coelicolor by Roszak, Aleksander W., Robinson, David A., Krell, Tino, Hunter, Iain S., Fredrickson, Martyn, Abell, Chris, Coggins, John R., Lapthorn, Adrian J.

    Published in Structure (London) (01-04-2002)
    “…The structure of the type II DHQase from Streptomyces coelicolor has been solved and refined to high resolution in complexes with a number of ligands,…”
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