Search Results - "Rosulek, Michal"
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Coordination and redox state–dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction
Published in The Journal of biological chemistry (22-12-2017)“…The heme-based oxygen sensor histidine kinase AfGcHK is part of a two-component signal transduction system in bacteria. O2 binding to the Fe(II) heme complex…”
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Binding of eIF3 in complex with eIF5 and eIF1 to the 40S ribosomal subunit is accompanied by dramatic structural changes
Published in Nucleic acids research (05-09-2019)“…Abstract eIF3 is a large multiprotein complex serving as an essential scaffold promoting binding of other eIFs to the 40S subunit, where it coordinates their…”
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Motif orientation matters: Structural characterization of TEAD1 recognition of genomic DNA
Published in Structure (London) (01-04-2021)“…TEAD transcription factors regulate gene expression through interactions with DNA and other proteins. They are crucial for the development of eukaryotic…”
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Proteases Immobilization for In Situ Time-Limited Proteolysis on MALDI Chips
Published in Catalysts (01-10-2019)“…A large number of different enzyme immobilization techniques are used in the field of life sciences, clinical diagnostics, or biotechnology. Most of them are…”
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MS-Based Approaches Enable the Structural Characterization of Transcription Factor/DNA Response Element Complex
Published in Biomolecules (Basel, Switzerland) (26-09-2019)“…The limited information available on the structure of complexes involving transcription factors and cognate DNA response elements represents a major obstacle…”
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The C-type lectin-like receptor Nkrp1b: Structural proteomics reveals features affecting protein conformation and interactions
Published in Journal of proteomics (30-03-2019)“…The cytotoxicity of mouse natural killer (NK) cells in response to pathological changes in target cells is regulated via the Nkrp1b receptor. Here, we…”
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Impact of Chemical Cross-Linking on Protein Structure and Function
Published in Analytical chemistry (Washington) (16-01-2018)“…Chemical cross-linking coupled with mass spectrometry is a popular technique for deriving structural information on proteins and protein complexes. Also,…”
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LinX: A Software Tool for Uncommon Cross-Linking Chemistry
Published in Journal of proteome research (02-04-2021)“…Chemical cross-linking mass spectrometry has become a popular tool in structural biology. Although several algorithms exist that efficiently analyze…”
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Protein Chips Compatible with MALDI Mass Spectrometry Prepared by Ambient Ion Landing
Published in Analytical chemistry (Washington) (06-09-2016)“…We present a technology that allows the preparation of matrix-assisted laser desorption/ionization (MALDI)-compatible protein chips by ambient ion landing of…”
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14‐3‐3 protein masks the nuclear localization sequence of caspase‐2
Published in The FEBS journal (01-11-2018)“…Caspase‐2 is an apical protease responsible for the proteolysis of cellular substrates directly involved in mediating apoptotic signaling cascades. Caspase‐2…”
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Mapping protein structural changes by quantitative cross-linking
Published in Methods (San Diego, Calif.) (01-11-2015)“…[Display omitted] •Quantification of calmodulin conformational changes with isotope-labeled cross-linkers.•Incomplete protein proteolysis hampers mass…”
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Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N-Glycosylation
Published in Cancers (21-07-2020)“…NKp30 is one of the main human natural killer (NK) cell activating receptors used in directed immunotherapy. The oligomerization of the NKp30 ligand binding…”
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13
Coordination and redox state-dependent structural changes of the heme-based oxygen sensor Af GcHK associated with intraprotein signal transduction
Published in The Journal of biological chemistry (22-12-2017)“…The heme-based oxygen sensor histidine kinase GcHK is part of a two-component signal transduction system in bacteria. O binding to the Fe(II) heme complex of…”
Get full text
Journal Article