Search Results - "Rostirolla, Diana Carolina"
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Extracellular HSP70 Activates ERK1/2, NF-kB and Pro-Inflammatory Gene Transcription Through Binding with RAGE in A549 Human Lung Cancer Cells
Published in Cellular physiology and biochemistry (01-10-2017)“…Background/Aims: Heat shock protein 70 (HSP70) has been recently described with extracellular actions, where it is actively released in inflammatory…”
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Chronic acrolein exposure in Wistar rats: The effects of guarana extracts
Published in Journal of functional foods (01-02-2020)“…Previous studies have reported that acrolein, may exert harmful effects on the brain. However, information regarding the neuroprotective properties of guarana…”
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Nuclear RXRα and RXRβ receptors exert distinct and opposite effects on RA-mediated neuroblastoma differentiation
Published in Biochimica et biophysica acta. Molecular cell research (01-03-2019)“…Retinoic acid (RA) promotes differentiation in multiple neurogenic cell types by promoting gene reprogramming through retinoid receptors and also by inducing…”
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Retinoic acid downregulates thiol antioxidant defences and homologous recombination while promotes A549 cells sensitization to cisplatin
Published in Cellular signalling (01-10-2019)“…Recent studies have investigated the use of retinoic acid (RA) molecule in combined chemotherapies to cancer cells as an attempt to increase treatment…”
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Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress
Published in Molecular neurobiology (01-11-2017)“…Human neuroblastoma SH-SY5Y cells have been used as an in vitro model for neurodegenerative disorders such as Parkinson’s disease and can be induced to a…”
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Synthesis and Evaluation of Thiazolyl-1H-benzo[ d ]imidazole Inhibitors of Mycobacterium tuberculosis Inosine Monophosphate Dehydrogenase
Published in Journal of the Brazilian Chemical Society (01-07-2015)“…Using an orthologue-based design approach, we synthesized and assayed a series of thiazolyl-1 H -benzo[ d ]imidazole derivatives as inhibitors of Mycobacterium…”
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The kinetic mechanism of Human Thymidine Phosphorylase - a molecular target for cancer drug development
Published in Molecular bioSystems (04-03-2014)“…Human Thymidine Phosphorylase (HTP), also known as the platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible…”
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