Search Results - "Rostami, Neda"
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Characterization of folic acid‐functionalized PLA–PEG nanomicelle to deliver Letrozole: A nanoinformatics study
Published in IET nanobiotechnology (01-06-2022)“…Effective cancer treatment is currently the number one challenge to human health. To date, several treatment methods have been introduced for cancer cell…”
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Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry
Published in Biotechnology advances (01-12-2020)“…Tag-assisted protein purification is a method of choice for both academic researches and large-scale industrial demands. Application of the purification tags…”
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Peptidomimetics in cancer targeting
Published in Molecular medicine (Cambridge, Mass.) (07-12-2022)“…The low efficiency of treatment strategies is one of the main obstacles to developing cancer inhibitors. Up to now, various classes of therapeutics have been…”
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Design, Synthesis, and Comparison of PLA-PEG-PLA and PEG-PLA-PEG Copolymers for Curcumin Delivery to Cancer Cells
Published in Polymers (01-07-2023)“…Curcumin (CUR) has potent anticancer activities, and its bioformulations, including biodegradable polymers, are increasingly able to improve CUR's solubility,…”
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Exploring Advanced CRISPR Delivery Technologies for Therapeutic Genome Editing
Published in Small science (01-10-2024)“…The genetic material within cells plays a pivotal role in shaping the structure and function of living organisms. Manipulating an organism's genome to correct…”
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CD44 polymorphisms and its variants, as an inconsistent marker in cancer investigations
Published in Mutation research. Reviews in mutation research (01-01-2021)“…Among cell surface markers, CD44 is considered the main marker for identifying and isolating the cancer stem cells (CSCs) among other cells and has attracted…”
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Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review
Published in Pharmacological reviews (01-03-2023)“…Among different types of breast cancers (BC), triple-negative BC (TNBC) amounts to 15% to 20% of breast malignancies. Three principal characteristics of TNBC…”
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Insight into molecular characteristics of SARS-CoV-2 spike protein following D614G point mutation, a molecular dynamics study
Published in Journal of biomolecular structure & dynamics (14-07-2022)“…Undoubtedly, the SARS-CoV-2 has become a major concern for all societies due to its catastrophic effects on public health. In addition, mutations and changes…”
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Doxorubicin-loaded Niosomes functionalized with gelatine and alginate as pH-responsive drug delivery system: A 3D printing approach
Published in International journal of biological macromolecules (31-12-2023)“…Despite many efforts, breast cancer remains one of the deadliest cancers and its treatment faces challenges related to cancer drug side effects and metastasis…”
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SARS‐CoV‐2 spike evolutionary behaviors; simulation of N501Y mutation outcomes in terms of immunogenicity and structural characteristic
Published in Journal of cellular biochemistry (01-02-2022)“…Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a large number of mutations in its genome have been reported. Some of the…”
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Evaluation of pH change effects on the HSA folding and its drug binding characteristics, a computational biology investigation
Published in Proteins, structure, function, and bioinformatics (01-11-2022)“…The binding of therapeutics to human serum albumin (HSA), which is an abundant protein in plasma poses a major challenge in drug discovery. Although HSA has…”
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Structural evolution of Delta lineage of SARS-CoV-2
Published in International journal of biological macromolecules (31-01-2023)“…One of the main obstacles in prevention and treatment of COVID-19 is the rapid evolution of the SARS-CoV-2 Spike protein. Given that Spike is the main target…”
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Peptide-functionalized polymeric nanoparticles for delivery of curcumin to cancer cells
Published in Journal of drug delivery science and technology (01-12-2024)“…Polymeric nanoparticles (NPs) have garnered significant interest due to their potential in drug delivery. Specifically, nanopolymers functionalized with…”
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Demographic characteristics and population projection of Phytonemus pallidus fragariae reared on different strawberry cultivars
Published in Experimental & applied acarology (01-12-2018)“…The strawberry mite, Phytonemus pallidus fragariae (Banks) (Acari: Tarsonemidae), is one of the most important pests of greenhouse grown strawberry plants…”
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Synthesis and Characterization of Folic Acid-Functionalized DPLA-co-PEG Nanomicelles for the Targeted Delivery of Letrozole
Published in ACS applied bio materials (15-05-2023)“…An effective treatment for hormone-dependent breast cancer is chemotherapy using cytotoxic agents such as letrozole (LTZ). However, most anticancer drugs,…”
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Implementation of docking, molecular dynamics and free energy to investigate drug potency of novel BCR-ABLT315I inhibitors as an alternative to ponatinib
Published in Computational toxicology (01-11-2021)“…•Among three candidate drugs, JNJ-26854165 gained a higher score but was not as potent as ponatinib.•Ponatinib had more potency and affinity to interact with…”
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Nature in the Murals on Vali-E-Asr Street in Tehran Influenced by the Identity of the Environment or a Purely Decorative Attitude? Evaluating the Relationships Between the Presence and Position of Nature with the Identity of the Environment in the Murals’ Context
Published in Manẓar (Online) (01-03-2023)“…The first trace of the changed living structures caused by the evolution of the new world in the city has emerged in the separation between humans and the…”
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