Search Results - "Rostami, Mahboubeh R."

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium by Zhang, Haijun, Rostami, Mahboubeh R, Leopold, Philip L, Mezey, Jason G, O'Beirne, Sarah L, Strulovici-Barel, Yael, Crystal, Ronald G

“…Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The…”
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The derepression of transposable elements in lung cells is associated with the inflammatory response and gene activation in idiopathic pulmonary fibrosis by Rostami, Mahboubeh R, Bradic, Martina

“…Transposable elements (TEs) are repetitive sequences of viral origin that compose almost half of the human genome. These elements are tightly controlled within…”
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Dysregulation of club cell biology in idiopathic pulmonary fibrosis by Zuo, Wu-Lin, Rostami, Mahboubeh R, LeBlanc, Michelle, Kaner, Robert J, O'Beirne, Sarah L, Mezey, Jason G, Leopold, Philip L, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. "Bronchiolization",…”
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Cell-specific expression of lung disease risk-related genes in the human small airway epithelium by Zuo, Wu-Lin, Rostami, Mahboubeh R, Shenoy, Shushila A, LeBlanc, Michelle G, Salit, Jacqueline, Strulovici-Barel, Yael, O'Beirne, Sarah L, Kaner, Robert J, Leopold, Philip L, Mezey, Jason G, Schymeinsky, Juergen, Quast, Karsten, Visvanathan, Sudha, Fine, Jay S, Thomas, Matthew J, Crystal, Ronald G

“…The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is…”
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Predicted deleterious variants in the human genome relevant to gene therapy with adeno-associated virus vectors by Rostami, Mahboubeh R., Leopold, Philip L., Vasquez, Jenifer M., de Mulder Rougvie, Miguel, Al Shakaki, Alya, Hssain, Ali Ait, Robay, Amal, Hackett, Neil R., Mezey, Jason G., Crystal, Ronald G.

“…Based on the observation that humans have variable responses of gene expression with the same dose of an adeno-associated vector, we hypothesized that there…”
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Smoking shifts human small airway epithelium club cells toward a lesser differentiated population by Rostami, Mahboubeh R., LeBlanc, Michelle G., Strulovici-Barel, Yael, Zuo, Wulin, Mezey, Jason G., O’Beirne, Sarah L., Kaner, Robert J., Leopold, Philip L., Crystal, Ronald G.

“…The club cell, a small airway epithelial (SAE) cell, plays a central role in human lung host defense. We hypothesized that subpopulations of club cells with…”
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The QChip1 knowledgebase and microarray for precision medicine in Qatar by Rodriguez-Flores, Juan L., Messai-Badji, Radja, Robay, Amal, Temanni, Ramzi, Syed, Najeeb, Markovic, Monika, Al-khayat, Eiman, Qafoud, Fatima, Nawaz, Zafar, Badii, Ramin, Al-Sarraj, Yasser, Mbarek, Hamdi, Al-Muftah, Wadha, Alvi, Muhammad, Rostami, Mahboubeh R., Cruzado, Juan Carlos Martinez, Mezey, Jason G., Shakaki, Alya Al, Malek, Joel A., Greenblatt, Matthew B., Fakhro, Khalid A., Machaca, Khaled, Al-Nabet, Ajayeb, Afifi, Nahla, Brooks, Andrew, Ismail, Said I., Althani, Asmaa, Crystal, Ronald G.

“…Risk genes for Mendelian (single-gene) disorders (SGDs) are consistent across populations, but pathogenic risk variants that cause SGDs are typically…”
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Serial Sampling of the Small Airway Epithelium to Identify Persistent Smoking-dysregulated Genes by Strulovici-Barel, Yael, Rostami, Mahboubeh R, Kaner, Robert J, Mezey, Jason G, Crystal, Ronald G

“…The small airway epithelium (beyond the sixth generation), the initiation site of smoking-induced airway disorders, is highly sensitive to the stress of…”
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Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors by Zhu, Detu, Rostami, Mahboubeh R, Zuo, Wu-Lin, Leopold, Philip L, Crystal, Ronald G

“…Capitalizing on liver tropism of adeno-associated viral (AAV) vectors, intravenous vector administration is commonly used to genetically modify hepatocytes, a…”
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Oral epithelium response of electronic cigarette users to electronic cigarette by Reeve, Gwendolyn S., Rostami, Mahboubeh R., Reich, Renee F., Behrman, David A., Leopold, Philip L., Crystal, Ronald G., Strulovici‐Barel, Yael

“…Background Electronic cigarettes are increasing in popularity, but there is only little information on their biologic effects on the oral epithelium, the…”
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Aggregate and Microcarrier Cultures of Human Pluripotent Stem Cells in Stirred-Suspension Systems by Ashok, Preeti, Fan, Yongjia, Rostami, Mahboubeh R, Tzanakakis, Emmanuel S

“…Pluripotent stem cells can differentiate to any cell type and contribute to damaged tissue repair and organ function reconstitution. The scalable culture of…”
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Dysregulation of club cell biology in idiopathic pulmonary fibrosis by Wu-Lin Zuo, Mahboubeh R. Rostami, Michelle LeBlanc, Robert J. Kaner, Sarah L. O’Beirne, Jason G. Mezey, Philip L. Leopold, Karsten Quast, Sudha Visvanathan, Jay S. Fine, Matthew J. Thomas, Ronald G. Crystal, Y. Peter Di

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic fibrotic lung disease with an irreversible decline of lung function. “Bronchiolization”,…”
Get full text