Search Results - "Rossmann, P"
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Assessment of stigma related to visible skin diseases: a systematic review and evaluation of patient‐reported outcome measures
Published in Journal of the European Academy of Dermatology and Venereology (01-04-2022)“…Misconceptions about visible skin diseases are widespread, and patients often face discrimination and stigmatization due to their condition. The associated…”
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Mitochondrial function in development and disease
Published in Disease models & mechanisms (01-06-2021)“…Mitochondria are organelles with vital functions in almost all eukaryotic cells. Often described as the cellular 'powerhouses' due to their essential role in…”
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Oral administration of Parabacteroides distasonis antigens attenuates experimental murine colitis through modulation of immunity and microbiota composition
Published in Clinical and experimental immunology (01-02-2011)“…Commensal bacteria have been shown to modulate the host mucosal immune system. Here, we report that oral treatment of BALB/c mice with components from the…”
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Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1
Published in Immunity (Cambridge, Mass.) (16-07-2019)“…Chronic inflammatory diseases are associated with altered hematopoiesis that could result in neutrophilia and anemia. Here we report that genetic or chemical…”
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A Common Telomeric Gene Silencing Assay Is Affected by Nucleotide Metabolism
Published in Molecular cell (08-04-2011)“…Telomere-associated position-effect variegation (TPEV) in budding yeast has been used as a model for understanding epigenetic inheritance and gene silencing. A…”
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The harlequin mouse mutation downregulates apoptosis-inducing factor
Published in Nature (London) (26-09-2002)“…Harlequin (Hq) mutant mice have progressive degeneration of terminally differentiated cerebellar and retinal neurons. We have identified the Hq mutation as a…”
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Development: For cloche the Bell Tolls
Published in Current biology (10-10-2016)“…A recent publication identifies npas4l as the gene defective in the well-known cloche mutant that lacks most endothelial as well as hematopoietic cells. This…”
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Surface Modification of Polyimide Sheets for Regenerative Medicine Applications
Published in Biomacromolecules (11-10-2010)“…In the present work, two strategies were elaborated to surface-functionalize implantable polyimide sheets. In the first methodology, cross-linkable vinyl…”
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Developmental regulation of primitive erythropoiesis
Published in Current opinion in hematology (01-05-2024)“…In this review, we present an overview of recent studies of primitive erythropoiesis, focusing on advances in deciphering its embryonic origin, defining…”
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‘Enhancing’ red cell fate through epigenetic mechanisms
Published in Current opinion in hematology (01-05-2021)“…Transcription of erythroid-specific genes is regulated by the three-dimensional (3D) structure and composition of chromatin, which dynamically changes during…”
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Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis
Published in Science (American Association for the Advancement of Science) (14-05-2021)“…Transcription and metabolism both influence cell function, but dedicated transcriptional control of metabolic pathways that regulate cell fate has rarely been…”
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Interaction of Mucosal Microbiota with the Innate Immune System
Published in Scandinavian journal of immunology (01-07-2005)“…Organisms live in continuos interaction with their environment; this interaction is of vital importance but at the same time can be life threatening. The…”
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Oral administration of probiotic bacteria (E. coli Nissle, E. coli O83, Lactobacillus casei) influences the severity of dextran sodium sulfate-induced colitis in BALB/c mice
Published in Folia microbiologica (01-01-2006)“…Our study examined whether repeated preventive oral administration of live probiotic bacterial strains Escherichia coli O83:K24:H31 (Ec O83), Escherichia coli…”
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14
Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis
Published in Proceedings of the National Academy of Sciences - PNAS (10-08-2021)“…Dyskeratosis congenita (DC) is a rare inherited bone marrow failure and cancer predisposition syndrome caused by mutations in telomerase or telomeric proteins…”
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Immunoblotting histones from yeast whole-cell protein extracts
Published in Cold Spring Harbor protocols (01-07-2013)“…Histones are small basic proteins that are core components of chromatin. As such, they are essential for cell viability and genomic stability and their levels…”
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The harlequin mouse mutation down-regulates apoptosis-inducing factor
Published in Nature (London) (26-09-2002)“…Harlequin (Hq) mutant mice have progressive degeneration of terminally differentiated cerebellar and retinal neurons. Klein et al have identified the Hq…”
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17
Chromatin immunoprecipitation and an open chromatin assay in zebrafish erythrocytes
Published in Methods in cell biology (2016)“…Zebrafish is an excellent genetic and developmental model for the study of vertebrate development and disease. Its ability to produce an abundance of…”
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The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases
Published in Cellular & molecular immunology (01-03-2011)“…Metagenomic approaches are currently being used to decipher the genome of the microbiota (microbiome), and, in parallel, functional studies are being performed…”
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The Influence of a Colonic Microbiota on HPMA Copolymer Lectin Conjugates Binding in Rodent Intestine
Published in Journal of drug targeting (01-01-2001)“…Germ-free (GF) animals lack a colonic microflora like that seen in conventional (CV) animals. Bacterial presence plays a role in the development of…”
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Ultrastructure of rat aortic grafts
Published in Folia microbiologica (01-01-1999)“…This study compares the ultrastructure of three syngeneic and three allogeneic grafts of rat abdominal aorta (Lewis to Lewis and BN to Lewis, respectively);…”
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