Search Results - "Rossin, Federica"

Celiac disease TG2 autoantibodies development: it takes two to tango by Rossin, Federica, Piacentini, Mauro

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Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75 by D’Eletto, Manuela, Rossin, Federica, Occhigrossi, Luca, Farrace, Maria Grazia, Faccenda, Danilo, Desai, Radha, Marchi, Saverio, Refolo, Giulia, Falasca, Laura, Antonioli, Manuela, Ciccosanti, Fabiola, Fimia, Gian Maria, Pinton, Paolo, Campanella, Michelangelo, Piacentini, Mauro

“…Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2…”
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The Multifaceted Role of HSF1 in Pathophysiology: Focus on Its Interplay with TG2 by Occhigrossi, Luca, D’Eletto, Manuela, Barlev, Nickolai, Rossin, Federica

“…The cellular environment needs to be strongly regulated and the maintenance of protein homeostasis is crucial for cell function and survival. HSF1 is the main…”
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The Role of Transglutaminase 2 in Cancer: An Update by Zaltron, Elisabetta, Vianello, Federica, Ruzza, Alessia, Palazzo, Alberta, Brillo, Valentina, Celotti, Ilaria, Scavezzon, Matteo, Rossin, Federica, Leanza, Luigi, Severin, Filippo

“…Transglutaminase type 2 (TG2) is the most ubiquitously expressed and well characterized member of the transglutaminase family. It is a ubiquitous…”
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Transglutaminase type 2 in the regulation of proteostasis by D'Eletto, Manuela, Rossin, Federica, Fedorova, Olga, Farrace, Maria Grazia, Piacentini, Mauro

“…The maintenance of protein homeostasis (proteostasis) is a fundamental aspect of cell physiology that is essential for the survival of organisms under a…”
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Transglutaminase 2 Regulates Innate Immunity by Modulating the STING/TBK1/IRF3 Axis by Occhigrossi, Luca, Rossin, Federica, D'Eletto, Manuela, Farrace, Maria Grazia, Ciccosanti, Fabiola, Petrone, Linda, Sacchi, Alessandra, Nardacci, Roberta, Falasca, Laura, Del Nonno, Franca, Palucci, Ivana, Smirnov, Evgeni, Barlev, Nick, Agrati, Chiara, Goletti, Delia, Delogu, Giovanni, Fimia, Gian Maria, Piacentini, Mauro

“…We have recently shown that type 2 transglutaminase (TG2) plays a key role in the host's inflammatory response during bacterial infections. In this study, we…”
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Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates by Rossin, Federica, Costa, Roberto, Bordi, Matteo, D’Eletto, Manuela, Occhigrossi, Luca, Farrace, Maria Grazia, Barlev, Nickolai, Ciccosanti, Fabiola, Muccioli, Silvia, Chieregato, Leonardo, Szabo, Ildiko, Fimia, Gian Maria, Piacentini, Mauro, Leanza, Luigi

“…TG2 is a multifunctional enzyme involved in several cellular processes and has emerging as a potential regulator of gene expression. In this regard, we have…”
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Cysteamine/Cystamine Exert Anti- Mycobacterium abscessus Activity Alone or in Combination with Amikacin by Palucci, Ivana, Salustri, Alessandro, De Maio, Flavio, Pereyra Boza, Maria Del Carmen, Paglione, Francesco, Sali, Michela, Occhigrossi, Luca, D'Eletto, Manuela, Rossin, Federica, Goletti, Delia, Sanguinetti, Maurizio, Piacentini, Mauro, Delogu, Giovanni

“…Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria. In…”
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Liquorice Toxicity: A Comprehensive Narrative Review by Ceccuzzi, Giovanna, Rapino, Alessandro, Perna, Benedetta, Costanzini, Anna, Farinelli, Andrea, Fiorica, Ilaria, Marziani, Beatrice, Cianci, Antonella, Rossin, Federica, Cesaro, Alice Eleonora, Spampinato, Michele Domenico, De Giorgio, Roberto, Guarino, Matteo

“…Background: Renowned since ancient times for its medical properties, liquorice is nowadays mainly used for flavoring candies or soft drinks. Continuous intake…”
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The STING/TBK1/IRF3/IFN type I pathway is defective in cystic fibrosis by Occhigrossi, Luca, Rossin, Federica, Villella, Valeria Rachela, Esposito, Speranza, Abbate, Carlo, D'Eletto, Manuela, Farrace, Maria Grazia, Tosco, Antonella, Nardacci, Roberta, Fimia, Gian Maria, Raia, Valeria, Piacentini, Mauro

“…Cystic fibrosis (CF) is a rare autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The most…”
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Transglutaminase 2 and Ferroptosis: a new liaison? by Gagliardi, Mara, Saverio, Valentina, Rossin, Federica, D’Eletto, Manuela, Corazzari, Marco

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Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2 by Piacentini, Mauro, Baiocchini, Andrea, Del Nonno, Franca, Melino, Gerry, Barlev, Nickolai A., Rossin, Federica, D’Eletto, Manuela, Falasca, Laura

“…Non-alcoholic fatty liver disease (NAFLD) is one of the most important liver diseases worldwide. Currently, no effective treatment is available, and NAFLD…”
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Transglutaminase Type 2-MITF axis regulates phenotype switching in skin cutaneous melanoma by Muccioli, Silvia, Brillo, Valentina, Varanita, Tatiana, Rossin, Federica, Zaltron, Elisabetta, Velle, Angelo, Alessio, Giorgia, Angi, Beatrice, Severin, Filippo, Tosi, Anna, D’Eletto, Manuela, Occhigrossi, Luca, Falasca, Laura, Checchetto, Vanessa, Ciaccio, Roberto, Fascì, Amelia, Chieregato, Leonardo, Rebelo, Ana Paula, Giacomello, Marta, Rosato, Antonio, Szabò, Ildikò, Romualdi, Chiara, Piacentini, Mauro, Leanza, Luigi

“…Skin cutaneous melanoma (SKCM) is the deadliest form of skin cancer due to its high heterogeneity that drives tumor aggressiveness. Melanoma plasticity…”
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Transglutaminase type 2-dependent crosslinking of IRF3 in dying melanoma cells by Occhigrossi, Luca, D’Eletto, Manuela, Vecchio, Alessio, Piacentini, Mauro, Rossin, Federica

“…cGAS/STING axis is the major executor of cytosolic dsDNA sensing that leads to the production of type I interferon (IFNI) not only upon bacterial infection,…”
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Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis by Villella, Valeria R., Esposito, Speranza, Ferrari, Eleonora, Monzani, Romina, Tosco, Antonella, Rossin, Federica, Castaldo, Alice, Silano, Marco, Marseglia, Gian Luigi, Romani, Luigina, Barlev, Nikolai A., Piacentini, Mauro, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi

“…Under physiological conditions, a finely tuned system of cellular adaptation allows the intestinal mucosa to maintain the gut barrier function while avoiding…”
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Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy by Alonzi, Tonino, Aiello, Alessandra, Petrone, Linda, Najafi Fard, Saeid, D'Eletto, Manuela, Falasca, Laura, Nardacci, Roberta, Rossin, Federica, Delogu, Giovanni, Castilletti, Concetta, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Piacentini, Mauro, Goletti, Delia

“…The ongoing pandemic of coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), needs better treatment…”
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Reticulon-1C Involvement in Muscle Regeneration by Rossin, Federica, Avitabile, Elena, Catarinella, Giorgia, Fornetti, Ersilia, Testa, Stefano, Oliverio, Serafina, Gargioli, Cesare, Cannata, Stefano, Latella, Lucia, Di Sano, Federica

“…Skeletal muscle is a very dynamic and plastic tissue, being essential for posture, locomotion and respiratory movement. Muscle atrophy or genetic muscle…”
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Type 2 transglutaminase in the nucleus: the new epigenetic face of a cytoplasmic enzyme by Rossin, Federica, Ciccosanti, Fabiola, D’Eletto, Manuela, Occhigrossi, Luca, Fimia, Gian Maria, Piacentini, Mauro

“…One of the major mysteries in science is how it is possible to pack the cellular chromatin with a total length of over 1 m, into a small sphere with a diameter…”
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Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions by Diaz-Hidalgo, Laura, Altuntas, Sara, Rossin, Federica, D'Eletto, Manuela, Marsella, Claudia, Farrace, Maria Grazia, Falasca, Laura, Antonioli, Manuela, Fimia, Gian Maria, Piacentini, Mauro

“…Numerous studies are revealing a role of exosomes in intercellular communication, and growing evidence indicates an important function for these vesicles in…”
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A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease by Villella, Valeria R, Venerando, Andrea, Cozza, Giorgio, Esposito, Speranza, Ferrari, Eleonora, Monzani, Romina, Spinella, Mara C, Oikonomou, Vasilis, Renga, Giorgia, Tosco, Antonella, Rossin, Federica, Guido, Stefano, Silano, Marco, Garaci, Enrico, Chao, Yu‐Kai, Grimm, Christian, Luciani, Alessandro, Romani, Luigina, Piacentini, Mauro, Raia, Valeria, Kroemer, Guido, Maiuri, Luigi

“…Intestinal handling of dietary proteins usually prevents local inflammatory and immune responses and promotes oral tolerance. However, in ~ 1% of the world…”
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