Search Results - "Rossin, Elizabeth"

The Pleiotropy of Complement Factor H by Rossin, Elizabeth J, Sobrin, Lucia

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Factors Associated With Increased Risk of Serious Ocular Injury in the Setting of Orbital Fracture by Rossin, Elizabeth J, Szypko, Colleen, Giese, Isaiah, Hall, Nathan, Gardiner, Matthew F, Lorch, Alice

“…Orbital fractures are common in ocular trauma, and there is a need to develop predictive tools to estimate risk of concurrent ocular injury. To identify…”
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Trends in Anti-Vascular Endothelial Growth Factor Original Medicare Part B Claims in the United States, 2014-2019 by Desai, Sarishka, Sekimitsu, Sayuri, Rossin, Elizabeth J, Zebardast, Nazlee

“…To characterize trends in use of and expenditure for the intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents aflibercept,…”
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Survey of variation in human transcription factors reveals prevalent DNA binding changes by Barrera, Luis A., Vedenko, Anastasia, Kurland, Jesse V., Rogers, Julia M., Gisselbrecht, Stephen S., Rossin, Elizabeth J., Woodard, Jaie, Mariani, Luca, Kock, Kian Hong, Inukai, Sachi, Siggers, Trevor, Shokri, Leila, Gordân, Raluca, Sahni, Nidhi, Cotsapas, Chris, Hao, Tong, Yi, Song, Kellis, Manolis, Daly, Mark J., Vidal, Marc, Hill, David E., Bulyk, Martha L.

“…Sequencing of exomes and genomes has revealed abundant genetic variation affecting the coding sequences of human transcription factors (TFs), but the…”
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Structure-guided T cell vaccine design for SARS-CoV-2 variants and sarbecoviruses by Nathan, Anusha, Rossin, Elizabeth J., Kaseke, Clarety, Park, Ryan J., Khatri, Ashok, Koundakjian, Dylan, Urbach, Jonathan M., Singh, Nishant K., Bashirova, Arman, Tano-Menka, Rhoda, Senjobe, Fernando, Waring, Michael T., Piechocka-Trocha, Alicja, Garcia-Beltran, Wilfredo F., Iafrate, A. John, Naranbhai, Vivek, Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that escape convalescent and vaccine-induced antibody responses has…”
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Structural topology defines protective CD8 + T cell epitopes in the HIV proteome by Gaiha, Gaurav D, Rossin, Elizabeth J, Urbach, Jonathan, Landeros, Christian, Collins, David R, Nwonu, Chioma, Muzhingi, Itai, Anahtar, Melis N, Waring, Olivia M, Piechocka-Trocha, Alicja, Waring, Michael, Worrall, Daniel P, Ghebremichael, Musie S, Newman, Ruchi M, Power, Karen A, Allen, Todd M, Chodosh, James, Walker, Bruce D

“…Mutationally constrained epitopes of variable pathogens represent promising targets for vaccine design but are not reliably identified by sequence…”
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Ophthalmic Trauma-Related Instruments-Critical Tools for Winning the Case by Sokol, Jared T, Rossin, Elizabeth J

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Effectiveness of a telemedicine program for triage and diagnosis of emergent ophthalmic conditions by Meshkin, Ryan S., Armstrong, Grayson W., Hall, Nathan E., Rossin, Elizabeth J., Hymowitz, Maggie B., Lorch, Alice C.

“…Background To study the utility of a teleophthalmology program to diagnose and triage common ophthalmic complaints presenting to an ophthalmic emergency room…”
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Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions by Raychaudhuri, Soumya, Plenge, Robert M, Rossin, Elizabeth J, Ng, Aylwin C Y, Purcell, Shaun M, Sklar, Pamela, Scolnick, Edward M, Xavier, Ramnik J, Altshuler, David, Daly, Mark J

“…Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but…”
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Targeting the Tie-2 Receptor With Faricimab in Central Serous Chorioretinopathy: A Case Series Motivated by a Genetic Finding by Rämö, Joel T., Kim, Leo A., Stryjewski, Tomasz, Shah, Priya P., Bejjani, Romy, Brodie, Frank L., Eliott, Dean, Sobrin, Lucia, Vavvas, Demetrios G., Rossin, Elizabeth J.

“…To investigate the effects of faricimab, a bispecific antibody targeting VEGF and Ang-2 (thus increasing Tie-2 activity), in patients with CSC based on a…”
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Single-cell RNA sequencing: An overview for the ophthalmologist by Rossin, Elizabeth J., Sobrin, Lucia, Kim, Leo A.

“…Understanding the molecular composition of pathogenic tissues is a critical step in understanding the pathophysiology of disease and designing therapeutics…”
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Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology by Rossin, Elizabeth J, Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J, Tatar, Diana, Benita, Yair, Cotsapas, Chris, Daly, Mark J

“…Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease…”
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Automated high-dimensional flow cytometric data analysis by Pyne, Saumyadipta, Hu, Xinli, Wang, Kui, Rossin, Elizabeth, Lin, Tsung -I, Maier, Lisa M, Baecher-Allan, Clare, McLachlan, Geoffrey J, Tamayo, Pablo, Hafler, David A, De Jager, Philip L, Mesirov, Jill P

“…Flow cytometric analysis allows rapid single cell interrogation of surface and intracellular determinants by measuring fluorescence intensity of…”
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HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV by Kaseke, Clarety, Park, Ryan J., Singh, Nishant K., Koundakjian, Dylan, Bashirova, Arman, Garcia Beltran, Wilfredo F., Takou Mbah, Overbeck C., Ma, Jiaqi, Senjobe, Fernando, Urbach, Jonathan M., Nathan, Anusha, Rossin, Elizabeth J., Tano-Menka, Rhoda, Khatri, Ashok, Piechocka-Trocha, Alicja, Waring, Michael T., Birnbaum, Michael E., Baker, Brian M., Carrington, Mary, Walker, Bruce D., Gaiha, Gaurav D.

“…Defining factors that govern CD8+ T cell immunodominance is critical for the rational design of vaccines for viral pathogens. Here, we assess the contribution…”
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Aflibercept for Retinopathy of Prematurity: A Systematic Review and Meta-Analysis by Chen, Po-Yu Jay, Rossin, Elizabeth J, Vavvas, Demetrios G

“…To determine the effectiveness of aflibercept in retinopathy of prematurity (ROP). We performed a systematic review and meta-analysis of proportions from the…”
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Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration by Rämö, Joel T, Abner, Erik, van Dijk, Elon H C, Wang, Xin, Brinks, Joost, Nikopensius, Tiit, Nõukas, Margit, Marjonen, Heidi, Silander, Kaisa, Jukarainen, Sakari, Kiiskinen, Tuomo, Choi, Seung Hoan, Kajanne, Risto, Mehtonen, Juha, Palta, Priit, Lubitz, Steven A, Kaarniranta, Kai, Sobrin, Lucia, Kurki, Mitja, Yzer, Suzanne, Ellinor, Patrick T, Esko, Tõnu, Daly, Mark J, den Hollander, Anneke I, Palotie, Aarno, Turunen, Joni A, Boon, Camiel J F, Rossin, Elizabeth J

“…Central serous chorioretinopathy (CSC) is a serous maculopathy of unknown etiology. Two of 3 previously reported CSC genetic risk loci are also associated with…”
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Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy by Delgado-Tirado, Santiago, Amarnani, Dhanesh, Zhao, Guannan, Rossin, Elizabeth J., Eliott, Dean, Miller, John B., Greene, Whitney A., Ramos, Leslie, Arevalo-Alquichire, Said, Leyton-Cifuentes, David, Gonzalez-Buendia, Lucia, Isaacs-Bernal, Daniela, Whitmore, Hannah A. B., Chmielewska, Natalia, Duffy, Brandon V., Kim, Eric, Wang, Heuy-Ching, Ruiz-Moreno, Jose M., Kim, Leo A., Arboleda-Velasquez, Joseph F.

“…Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it…”
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Two Cases of Cutibacterium acnes ( C acnes ) Endophthalmitis Manifesting With Unusual Epiretinal Deposits by Rossin, Elizabeth J, Tieger, Marisa, Rao, Narsing A, O'Hearn, Thomas M, Eliott, Dean, Wu, David M

“…This article describes two cases of delayed-onset ( ) endophthalmitis 1 month after cataract surgery manifesting with unusual epiretinal deposits. Both…”
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Hypopyon and White Cataract Due to an Intraocular Helminth by Wai, Karen M, Rossin, Elizabeth J, Delgado-Tirado, Santiago, Cadorette, James J, Boody, Rick P, Rodriguez, Marianeli, Kim, Leo A

“…We describe a case of a 29-year-old man with a history of intravenous drug use and vague history of eye trauma who presented with a hypopyon and white cataract…”
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Structure-based network analysis predicts pathogenic variants in human proteins associated with inherited retinal disease by Hauser, Blake M., Luo, Yuyang, Nathan, Anusha, Al-Moujahed, Ahmad, Vavvas, Demetrios G., Comander, Jason, Pierce, Eric A., Place, Emily M., Bujakowska, Kinga M., Gaiha, Gaurav D., Rossin, Elizabeth J.

“…Advances in gene sequencing technologies have accelerated the identification of genetic variants, but better tools are needed to understand which are causal of…”
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