Search Results - "Rossignol, Rodrigue"

High glucose repatterns human podocyte energy metabolism during differentiation and diabetic nephropathy by Imasawa, Toshiyuki, Obre, Emilie, Bellance, Nadège, Lavie, Julie, Imasawa, Tomoko, Rigothier, Claire, Delmas, Yahsou, Combe, Christian, Lacombe, Didier, Benard, Giovanni, Claverol, Stéphane, Bonneu, Marc, Rossignol, Rodrigue

“…Podocytes play a key role in diabetic nephropathy pathogenesis, but alteration of their metabolism remains unknown in human kidney. By using a conditionally…”
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Ultrastructure of the mitochondrion and its bearing on function and bioenergetics by Benard, Giovanni, Rossignol, Rodrigue

“…The recently ascertained network and dynamic organization of the mitochondrion, as well as the demonstration of energy proteins and metabolites…”
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Mitochondria participate in chemoresistance to cisplatin in human ovarian cancer cells by Zampieri, Luca X, Grasso, Debora, Bouzin, Caroline, Brusa, Davide, Rossignol, Rodrigue, Sonveaux, Pierre

“…Ovarian cancer is an aggressive disease that affects about 300,000 patients worldwide, with a yearly death count of about 185,000. Following surgery, treatment…”
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Mitochondrial bioenergetics and structural network organization by Benard, Giovanni, Bellance, Nadège, James, Dominic, Parrone, Philippe, Fernandez, Helder, Letellier, Thierry, Rossignol, Rodrigue

“…Mitochondria form a dynamic network, and it remains unclear how the alternate configurations interact with bioenergetics properties. The metabolic signals that…”
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Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F by Esteves, Pauline, Dard, Laetitia, Brillac, Aurélia, Hubert, Christophe, Sarlak, Saharnaz, Rousseau, Benoît, Dumon, Elodie, Izotte, Julien, Bonneu, Marc, Lacombe, Didier, Dupuy, Jean-William, Amoedo, Nivea, Rossignol, Rodrigue

“…The basic understanding of the biological effects of eukaryotic translation initiation factors (EIFs) remains incomplete, notably for their roles independent…”
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Rationale for mitochondria-targeting strategies in cancer bioenergetic therapies by Jose, Caroline, Rossignol, Rodrigue

“…In the 1920s, Otto Warburg first hypothesized that mitochondrial impairment is a leading cause of cancer although he recognized the existence of oxidative…”
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Mitochondria: from bioenergetics to the metabolic regulation of carcinogenesis by Bellance, Nadege, Lestienne, Patrick, Rossignol, Rodrigue

“…In this review, we discuss the concept of metabolic remodeling and signaling in tumors, specifically the various metabolites that participate in the regulation…”
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Proteomic Study of Low-Birth-Weight Nephropathy in Rats by Imasawa, Toshiyuki, Claverol, Stéphane, Lacombe, Didier, Amoedo, Nivea Dias, Rossignol, Rodrigue

“…The hyperfiltration theory has been used to explain the mechanism of low birth weight (LBW)-related nephropathy. However, the molecular changes in the kidney…”
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Human F1F0 ATP synthase, mitochondrial ultrastructure and OXPHOS impairment: a (super-)complex matter? by Habersetzer, Johann, Larrieu, Isabelle, Priault, Muriel, Salin, Bénédicte, Rossignol, Rodrigue, Brèthes, Daniel, Paumard, Patrick

“…Mitochondrial morphogenesis is a key process of cell physiology. It is essential for the proper function of this double membrane-delimited organelle, as it…”
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Mitoplasticity: adaptation biology of the mitochondrion to the cellular redox state in physiology and carcinogenesis by Jose, Caroline, Melser, Su, Benard, Giovanni, Rossignol, Rodrigue

“…Adaptation and transformation biology of the mitochondrion to redox status is an emerging domain of physiology and pathophysiology. Mitochondrial adaptations…”
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Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells by Zampieri, Luca X, Sboarina, Martina, Cacace, Andrea, Grasso, Debora, Thabault, Léopold, Hamelin, Loïc, Vazeille, Thibaut, Dumon, Elodie, Rossignol, Rodrigue, Frédérick, Raphaël, Sonveaux, Etienne, Lefranc, Florence, Sonveaux, Pierre

“…Glioblastoma represents the highest grade of brain tumors. Despite maximal resection surgery associated with radiotherapy and concomitant followed by adjuvant…”
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Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells by Bellance, Nadège, Furt, Fabienne, Melser, Su, Lalou, Claude, Thoraval, Didier, Maneta-Peyret, Lilly, Lacombe, Didier, Moreau, Patrick, Rossignol, Rodrigue

“…Doxorubicin (DXR) is a drug widely used in chemotherapy. Its mode of action is based on its intercalation properties, involving the inhibition of topoisomerase…”
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HRAS germline mutations impair LKB1/AMPK signaling and mitochondrial homeostasis in Costello syndrome models by Dard, Laetitia, Hubert, Christophe, Esteves, Pauline, Blanchard, Wendy, Bou About, Ghina, Baldasseroni, Lyla, Dumon, Elodie, Angelini, Chloe, Delourme, Mégane, Guyonnet-Dupérat, Véronique, Claverol, Stéphane, Fontenille, Laura, Kissa, Karima, Séguéla, Pierre-Emmanuel, Thambo, Jean-Benoît, Nicolas, Lévy, Herault, Yann, Bellance, Nadège, Dias Amoedo, Nivea, Magdinier, Frédérique, Sorg, Tania, Lacombe, Didier, Rossignol, Rodrigue

“…Germline mutations that activate genes in the canonical RAS/MAPK signaling pathway are responsible for rare human developmental disorders known as RASopathies…”
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Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells by ROSSIGNOL, Rodrigue, GILKERSON, Robert, AGGELER, Robert, YAMAGATA, Kunihiro, REMINGTON, S. James, CAPALDI, Roderick A

“…Comparative analysis of cytoplasmic organelles in a variety of tumors relative to normal tissues generally reveals a strong diminution in mitochondrial content…”
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Quantitative Proteomics Analysis Reveals That Cyclooxygenase-2 Modulates Mitochondrial Respiratory Chain Complex IV in Cardiomyocytes by Alvarez, Maria Soledad, Núñez, Estefanía, Fuertes-Agudo, Marina, Cucarella, Carme, Fernandez-Velasco, Maria, Boscá, Lisardo, Vázquez, Jesús, Rossignol, Rodrigue, Martin-Sanz, Paloma, Casado, Marta

“…The biochemical mechanisms of cell injury and myocardial cell death after myocardial infarction remain unresolved. Cyclooxygenase 2 (COX-2), a key enzyme in…”
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Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma by Trian, Thomas, Benard, Giovanni, Begueret, Hugues, Rossignol, Rodrigue, Girodet, Pierre-Olivier, Ghosh, Debajyoti, Ousova, Olga, Vernejoux, Jean-Marc, Marthan, Roger, Tunon-de-Lara, José-Manuel, Berger, Patrick

“…Asthma and chronic obstructive pulmonary disease (COPD) are characterized by different patterns of airway remodeling, which all include an increased mass of…”
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Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor by Hebert-Chatelain, Etienne, Reguero, Leire, Puente, Nagore, Lutz, Beat, Chaouloff, Francis, Rossignol, Rodrigue, Piazza, Pier-Vincenzo, Benard, Giovanni, Grandes, Pedro, Marsicano, Giovanni

“…Abstract Brain mitochondrial activity is centrally involved in the central control of energy balance. When studying mitochondrial functions in the brain,…”
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A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity by Perrin-Cocon, Laure, Vidalain, Pierre-Olivier, Jacquemin, Clémence, Aublin-Gex, Anne, Olmstead, Keedrian, Panthu, Baptiste, Rautureau, Gilles Jeans Philippe, André, Patrice, Nyczka, Piotr, Hütt, Marc-Thorsten, Amoedo, Nivea, Rossignol, Rodrigue, Filipp, Fabian Volker, Lotteau, Vincent, Diaz, Olivier

“…During the cancerous transformation of normal hepatocytes into hepatocellular carcinoma (HCC), the enzyme catalyzing the first rate-limiting step of…”
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Distinctions and similarities of cell bioenergetics and the role of mitochondria in hypoxia, cancer, and embryonic development by Ježek, Petr, Plecitá-Hlavatá, Lydie, Smolková, Katarína, Rossignol, Rodrigue

“…In this review we compare situations under which the major cellular role of mitochondria, oxidative phosphorylation (OXPHOS), is transiently suppressed. Two…”
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Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model by Dai, Wangde, Amoedo, Nivea Dias, Perry, Justin, Le Grand, Bruno, Boucard, Aurelie, Carreno, Juan, Zhao, Lifu, Brown, David A., Rossignol, Rodrigue, Kloner, Robert A.

“…Purpose The present study was to determine whether OP2113 could limit myocardial infarction size and the no-reflow phenomenon in a rat myocardial…”
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