Search Results - "Rossignol, Patrick"
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Cardiorenal Syndrome Revisited
Published in Circulation (New York, N.Y.) (28-08-2018)“…Cardiorenal syndromes have been categorized into 5 clinical subtypes based on which organ is perceived to be the primary precipitant of the vicious and…”
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Epidemiology, contributors to, and clinical trials of mortality risk in chronic kidney failure
Published in The Lancet (British edition) (24-05-2014)“…Summary Patients with chronic kidney failure—defined as a glomerular filtration rate persistently below 15 mL/min per 1·73 m2 —have an unacceptably high…”
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Evaluation of kidney function throughout the heart failure trajectory – a position statement from the Heart Failure Association of the European Society of Cardiology
Published in European journal of heart failure (01-04-2020)“…Appropriate interpretation of changes in markers of kidney function is essential during the treatment of acute and chronic heart failure. Historically, kidney…”
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Prognostic value of residual pulmonary congestion at discharge assessed by lung ultrasound imaging in heart failure
Published in European journal of heart failure (01-11-2015)“…Aims Residual pulmonary congestion at discharge is associated with poor prognosis in heart failure (HF), but its quantification through physical examination is…”
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Abnormalities of Potassium in Heart Failure
Published in Journal of the American College of Cardiology (09-06-2020)“…Potassium (K+) is the most abundant cation in humans and is essential for normal cellular function. Alterations in K+ regulation can lead to neuromuscular,…”
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Galectin-3 Mediates Aldosterone-Induced Vascular Fibrosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-01-2013)“…OBJECTIVE—Aldosterone (Aldo) is involved in arterial stiffness and heart failure, but the mechanisms have remained unclear. Galectin-3 (Gal-3), a…”
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Differentiation between emerging non-steroidal and established steroidal mineralocorticoid receptor antagonists: head-to-head comparisons of pharmacological and clinical characteristics
Published in Expert opinion on investigational drugs (02-11-2021)“…Mineralocorticoid receptor (MR) antagonists (MRAs) provide cardiorenal protection. However steroidal MRAs might induce hyperkalemia and sex hormone-related…”
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Long-Term Potassium Monitoring and Dynamics in Heart Failure and Risk of Mortality
Published in Circulation (New York, N.Y.) (27-03-2018)“…BACKGROUND:The prognostic value of long-term potassium monitoring and dynamics in heart failure has not been characterized completely. We sought to determine…”
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9
Prognostic Value of Estimated Plasma Volume in Heart Failure
Published in JACC. Heart failure (01-11-2015)“…Abstract Objectives The purpose of this study was to assess the prognostic value of the estimation of plasma volume or of its variation beyond clinical…”
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10
Influence of Baseline and Worsening Renal Function on Efficacy of Spironolactone in Patients With Severe Heart Failure
Published in Journal of the American College of Cardiology (13-11-2012)“…Objectives This study investigated the influence of baseline and worsening renal function (WRF) on the efficacy of spironolactone in patients with severe heart…”
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11
The Impact of Galectin-3 Inhibition on Aldosterone-Induced Cardiac and Renal Injuries
Published in JACC. Heart failure (2015)“…Abstract Objectives This study investigated whether galectin (Gal)-3 inhibition could block aldosterone-induced cardiac and renal fibrosis and improve…”
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12
Galectin-3 Blockade Inhibits Cardiac Inflammation and Fibrosis in Experimental Hyperaldosteronism and Hypertension
Published in Hypertension (Dallas, Tex. 1979) (01-10-2015)“…Hypertensive cardiac remodeling is accompanied by molecular inflammation and fibrosis, 2 mechanisms that finally affect cardiac function. At cardiac level,…”
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13
Geographic differences in heart failure trials
Published in European journal of heart failure (01-09-2015)“…Randomized controlled trials (RCTs) are essential to develop advances in heart failure (HF). The need for increasing numbers of patients (without substantial…”
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14
Galectin-3 Blockade Reduces Renal Fibrosis in Two Normotensive Experimental Models of Renal Damage
Published in PloS one (09-11-2016)“…Galectin-3 (Gal-3), a β-galactoside-binding lectin, is increased in kidney injury and its pharmacological blockade reduces renal damage in acute kidney injury,…”
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Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH)
Published in Nephrology, dialysis, transplantation (01-04-2017)“…In patients with end-stage renal disease (ESRD) treated with haemodialysis or peritoneal dialysis, hypertension is common and often poorly controlled. Blood…”
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The double challenge of resistant hypertension and chronic kidney disease
Published in The Lancet (British edition) (17-10-2015)“…Summary Resistant hypertension is defined as blood pressure above goal despite adherence to a combination of at least three optimally dosed antihypertensive…”
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17
Head-to-head comparison of clustering methods for heterogeneous data: a simulation-driven benchmark
Published in Scientific reports (18-02-2021)“…The choice of the most appropriate unsupervised machine-learning method for “heterogeneous” or “mixed” data, i.e. with both continuous and categorical…”
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Diagnostic performance of congestion score index evaluated from chest radiography for acute heart failure in the emergency department: A retrospective analysis from the PARADISE cohort
Published in PLoS medicine (11-11-2020)“…Congestion score index (CSI), a semiquantitative evaluation of congestion on chest radiography (CXR), is associated with outcome in patients with heart failure…”
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Management of hyperkalemia in the acutely ill patient
Published in Annals of intensive care (28-02-2019)“…Purpose To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. Methods We…”
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Sex differences in mineralocorticoid receptor antagonist trials: a pooled analysis of three large clinical trials
Published in European journal of heart failure (01-05-2020)“…Aims Women with heart failure (HF) are under‐represented in individual randomized clinical trials (RCTs). Little is known about sex‐specific treatment effects…”
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