Search Results - "Rossi, Rachele"
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Innovative Therapeutic Approaches for Duchenne Muscular Dystrophy
Published in Journal of clinical medicine (17-02-2021)“…Duchenne muscular dystrophy (DMD) is the most common childhood muscular dystrophy affecting ~1:5000 live male births. Following the identification of…”
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COVID-19-Induced Modifications in the Tumor Microenvironment: Do They Affect Cancer Reawakening and Metastatic Relapse?
Published in Frontiers in oncology (26-10-2020)“…Severe coronavirus disease 2019 (COVID-19) causes an uncontrolled activation of the innate immune response, resulting in acute respiratory distress syndrome…”
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Calculating and comparing codon usage values in rare disease genes highlights codon clustering with disease-and tissue- specific hierarchy
Published in PloS one (31-03-2022)“…We designed a novel strategy to define codon usage bias (CUB) in 6 specific small cohorts of human genes. We calculated codon usage (CU) values in 29…”
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A new potentially toxic Azadinium species (Dinophyceae) from the Mediterranean Sea, A. dexteroporum sp. nov
Published in Journal of phycology (01-10-2013)“…A new photosynthetic planktonic marine dinoflagellate, Azadinium dexteroporum sp. nov., is described from the Gulf of Naples (South Tyrrhenian Sea,…”
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5
MyoD-induced reprogramming of human fibroblasts and urinary stem cells in vitro : protocols and their applications
Published in Frontiers in physiology (17-05-2023)“…The conversion of fibroblasts into myogenic cells is a powerful tool to both develop and test therapeutic strategies and to perform in-depth investigations of…”
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Synaptic Vesicle Glycoprotein 2A: Features and Functions
Published in Frontiers in neuroscience (28-04-2022)“…In recent years, the field of neuroimaging dramatically moved forward by means of the expeditious development of specific radioligands of novel targets. Among…”
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New palytoxin-like molecules in Mediterranean Ostreopsis cf. ovata (dinoflagellates) and in Palythoa tuberculosa detected by liquid chromatography-electrospray ionization time-of-flight mass spectrometry
Published in Toxicon (Oxford) (01-12-2010)“…A rapid, high resolution liquid chromatography coupled with ElectroSpray Ionization Time-Of-Flight Mass Spectrometry (ESI/TOF/MS) method was developed for the…”
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Phenological segregation suggests speciation by time in the planktonic diatom Pseudo‐nitzschia allochrona sp. nov
Published in Ecology and evolution (01-08-2022)“…The processes leading to the emergence of new species are poorly understood in marine plankton, where weak physical barriers and homogeneous environmental…”
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A Proof of Principle Proteomic Study Detects Dystrophin in Human Plasma: Implications in DMD Diagnosis and Clinical Monitoring
Published in International journal of molecular sciences (01-03-2023)“…Duchenne muscular dystrophy (DMD) is a rare neuromuscular disease caused by pathogenic variations in the gene. There is a need for robust DMD biomarkers for…”
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A nanoencapsulated oral formulation of fenretinide promotes local and metastatic breast cancer dormancy in HER2/neu transgenic mice
Published in Journal of experimental & clinical cancer research (05-11-2024)“…Abstract Background Prevention and treatment of metastatic breast cancer (BC) is an unmet clinical need. The retinoic acid derivative fenretinide (FeR) was…”
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Repeated Exposure to Subinfectious Doses of SARS-CoV-2 May Promote T Cell Immunity and Protection against Severe COVID-19
Published in Viruses (22-05-2021)“…Europe is experiencing a third wave of COVID-19 due to the spread of highly transmissible SARS-CoV-2 variants. A number of positive and negative factors…”
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Vaccine-induced massive pulmonary embolism and thrombocytopenia following a single dose of Janssen Ad26.COV2.S vaccination
Published in International journal of infectious diseases (01-03-2022)“…•Thrombosis and thrombocytopenia after SARS-CoV-2 viral vector vaccine suggests vaccine-induced immune thrombotic thrombocytopenia (VITT).•Thrombosis in…”
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Growth and toxicity responses of Mediterranean Ostreopsis cf. ovata to seasonal irradiance and temperature conditions
Published in Harmful algae (01-05-2012)“…► We describe the temperature-irradiance growth response of Ostreopsis cf. ovate from the Mediterranean. ► Temperature constrains growth between 18 and 30°C,…”
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Biological Effects of the Azaspiracid-Producing Dinoflagellate Azadinium dexteroporum in Mytilus galloprovincialis from the Mediterranean Sea
Published in Marine drugs (22-10-2019)“…Azaspiracids (AZAs) are marine biotoxins including a variety of analogues. Recently, novel AZAs produced by the Mediterranean dinoflagellate were discovered…”
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Duchenne Muscular Dystrophy Myogenic Cells from Urine-Derived Stem Cells Recapitulate the Dystrophin Genotype and Phenotype
Published in Human gene therapy (01-10-2016)“…A ready source of autologous myogenic cells is of vital importance for drug screening and functional genetic studies in Duchenne muscular dystrophy (DMD), a…”
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CRIPTO Is a Marker of Chemotherapy-Induced Stem Cell Expansion in Non-Small Cell Lung Cancer
Published in Frontiers in oncology (02-06-2022)“…Chemotherapy is the mainstay for the treatment of non-small cell lung cancer (NSCLC). However, NSCLC cells are either intrinsically chemoresistant or rapidly…”
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Urine-Derived Stem Cells Express 571 Neuromuscular Disorders Causing Genes, Making Them a Potential in vitro Model for Rare Genetic Diseases
Published in Frontiers in physiology (20-10-2021)“…Background: Neuromuscular disorders (NMDs) are a heterogeneous group of genetic diseases, caused by mutations in genes involved in spinal cord, peripheral…”
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Circadian Genes as Exploratory Biomarkers in DMD: Results From Both the mdx Mouse Model and Patients
Published in Frontiers in physiology (08-07-2021)“…Duchenne muscular dystrophy (DMD) is a rare genetic disease due to dystrophin gene mutations which cause progressive weakness and muscle wasting. Circadian…”
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Efficacy of convalescent plasma therapy in immunocompromised patients with COVID-19: A case report
Published in Clinical infection in practice (01-11-2021)“…•Accumulating evidence suggest that treatment with high-titer COVID-19 convalescent plasma (CCP) may be effective in immunocompromised COVID-19…”
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RNA-seq in DMD urinary stem cells recognized muscle-related transcription signatures and addressed the identification of atypical mutations by whole-genome sequencing
Published in HGG advances (13-01-2022)“…Urinary stem cells (USCs) are a non-invasive, simple, and affordable cell source to study human diseases. Here we show that USCs are a versatile tool for…”
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