Search Results - "Rossi, Gustavo R."
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Dichotomous outcomes of TNFR1 and TNFR2 signaling in NK cell-mediated immune responses during inflammation
Published in Nature communications (14-11-2024)“…Natural killer (NK) cell function is regulated by a balance of activating and inhibitory signals. Tumor necrosis factor (TNF) is an inflammatory cytokine…”
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Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β
Published in Frontiers in immunology (01-05-2019)“…We characterized the NK cell phenotype and function in three family members with Hereditary Hemorrhagic Telangiectasia (HHT) due to heterozygous mutations…”
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Development of Physiologically Relevant Skin Organoids from Human Induced Pluripotent Stem Cells
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2024)“…The development of skin organs for studying developmental pathways, modeling diseases, or regenerative medicine purposes is a major endeavor in the field…”
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CIS and TGF‐β regulatory pathways influence immunity to bacterial infection
Published in Immunology (01-09-2022)“…Immunotherapy has revolutionized cancer therapy by reactivating tumour‐resident cytotoxic lymphocytes. More recently, immunotherapy has emerged to restore…”
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A scalable, spin-free approach to generate enhanced induced pluripotent stem cell-derived natural killer cells for cancer immunotherapy
Published in Immunology and cell biology (01-11-2024)“…Natural killer (NK) cells play a vital role in innate immunity and show great promise in cancer immunotherapy. Traditional sources of NK cells, such as the…”
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The immune checkpoint TIGIT is upregulated on T cells during bacterial infection and is a potential target for immunotherapy
Published in Immunology and cell biology (01-09-2024)“…Antibiotic resistance is a major public health threat, and alternatives to antibiotic therapy are urgently needed. Immunotherapy, particularly the blockade of…”
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Viscera of fishes as raw material for extraction of glycosaminoglycans of pharmacological interest
Published in International journal of biological macromolecules (01-01-2019)“…World fisheries and aquaculture production totaled 167 million tons in 2014. This high fish production generates a lot of waste that could be used as raw…”
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Biocompatible gum arabic-gold nanorod composite as an effective therapy for mistreated melanomas
Published in International journal of biological macromolecules (31-08-2021)“…Advanced melanoma patients that are not included in common genetic classificatory groups lack effective and safe therapeutic options. Chemotherapy and…”
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Monoclonal Antibody DL11C8 Identifies ADAM23 as a Component of Lipid Raft Microdomains
Published in Neuroscience (01-08-2018)“…•Monoclonal antibody DL11C8 specifically recognizes ADAM23 from different species.•ADAM23 is highly expressed in tumoral cell lineages of the central nervous…”
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The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation
Published in Journal of clinical medicine (18-08-2020)“…Natural killer (NK) cells are innate lymphocytes responsible for the elimination of infected or transformed cells. The activation or inhibition of NK cells is…”
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Effect of pegylated phosphatidylserine-containing liposomes in experimental chronic arthritis
Published in BMC pharmacology & toxicology (22-09-2015)“…Phosphatidylserine-containing liposomes (PSL) have been shown to reduce inflammation in experimental models of acute arthritis, by mimicking the apoptotic…”
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Loss-of-Function in SMAD4 Might Not Be Critical for Human Natural Killer Cell Responsiveness to TGF-β
Published in Frontiers in immunology (01-01-2019)“…We characterized the NK cell phenotype and function in three family members with Hereditary Hemorrhagic Telangiectasia (HHT) due to heterozygous SMAD4…”
Get full text
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