Search Results - "Rossetti, Ilaria"
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Cholinergic Modulation of Glial Function During Aging and Chronic Neuroinflammation
Published in Frontiers in cellular neuroscience (15-10-2020)“…Ageing is a complex biological process which increases the risk of age-related cognitive degenerative diseases such as dementia, including Alzheimer’s disease…”
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Neuromodulation of Glial Function During Neurodegeneration
Published in Frontiers in cellular neuroscience (21-08-2020)“…Glia, a non-excitable cell type once considered merely as the connective tissue between neurons, is nowadays acknowledged for its essential contribution to…”
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Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum
Published in Journal of neuroinflammation (13-10-2023)“…Abstract Background Low-grade, chronic inflammation in the central nervous system characterized by glial reactivity is one of the major hallmarks for…”
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THE IMPACT OF CHRONIC NEUROINFLAMMATION AND AGING ON THE CHOLINERGIC SYSTEM AND THE THERAPEUTIC POTENTIAL OF MERIVA CURCUMIN
Published in IBRO neuroscience reports (01-10-2023)Get full text
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From the Bush to the Brain: Preclinical Stages of Ethnobotanical Anti-Inflammatory and Neuroprotective Drug Discovery-An Australian Example
Published in International journal of molecular sciences (01-07-2023)“…The Australian rainforest is a rich source of medicinal plants that have evolved in the face of dramatic environmental challenges over a million years due to…”
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Turnover rate of coenzyme A in mouse brain and liver
Published in PloS one (21-05-2021)“…Coenzyme A (CoA) is a fundamental cofactor involved in a number of important biochemical reactions in the cell. Altered CoA metabolism results in severe…”
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Reducing unwanted catches of trammel nets: experimental results of the “guarding net” in the caramote prawn, Penaeus kerathurus, small-scale fishery of the Ligurian Sea (western Mediterranean)
Published in Scientia marina (01-12-2018)“…This study aimed to test the effectiveness of a “guarding net”, a device placed at the bottom of a trammel net, for reducing unwanted catches in the caramote…”
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The MEDITS maturity scales as a useful tool for investigating the reproductive traits of key species in the Mediterranean Sea
Published in Scientia marina (01-12-2019)“…Maturity is one of the most important biological parameters used in stock assessment programmes. Indeed, the macroscopic stage of gonadal development is an…”
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Predisposition to Alcohol Drinking and Alcohol Consumption Alter Expression of Calcitonin Gene-Related Peptide, Neuropeptide Y, and Microglia in Bed Nucleus of Stria Terminalis in a Subnucleus-Specific Manner
Published in Frontiers in cellular neuroscience (30-04-2019)“…Excessive alcohol consumption is often linked to anxiety states and has a major relay center in the anterior part of bed nucleus of stria terminalis (BNST). We…”
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Testing experimental devices in the extension piece to increase the selectivity of bottom trawl in the Nw Mediterranean
Published in Frontiers in Marine Science (21-12-2022)“…In the Mediterranean, experiments and technical measures aimed at improving the selectivity of bottom trawl nets mostly concern modifications to the codend…”
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Azide-free synthesis of Boc-protected (3R,4S)-3,4-dihydroxypiperidine
Published in Tetrahedron letters (11-05-2022)“…[Display omitted] Boc-protected (3R,4S)-3,4-dihydroxypiperidine diol 1 is an enantiomerically pure, highly valuable synthetic intermediate. Herein we report…”
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Calcitonin gene-related peptide decreases IL-1beta, IL-6 as well as Ym1, Arg1, CD163 expression in a brain tissue context-dependent manner while ameliorating experimental autoimmune encephalomyelitis
Published in Journal of neuroimmunology (15-10-2018)“…Activation states of immune cells (among them, the so-called pro- or anti-inflammatory states) influence the pathogenesis of multiple sclerosis (MS). The…”
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Astrocytic K+ clearance during disease progression in amyotrophic lateral sclerosis
Published in Glia (01-10-2023)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder in which patients lose motor functions due to progressive loss of motor neurons in the…”
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A stereological study of glial activation in GFAP‐IL6 mice: A model of chronic neuroimmune conditions
Published in Alzheimer's & dementia (01-12-2021)“…Background Understanding the role of chronic neuroinflammation, described by increased astro‐ and microglia activation, in the pathogenesis of Alzheimer’s…”
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Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration
Published in Journal of medicinal chemistry (24-12-2020)“…Mutations in the human PANK2 gene are implicated in neurodegenerative diseases such as pantothenate kinase-associated neurodegeneration (PKAN) and result in…”
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Bakchias alla luce delle ultime scoperte: topografia e urbanistica
Published in Aegyptus (01-01-2013)“…The latest studies of the Bologna University about the scientific expedition at Bakchias (Kom Umm el-Atl), carried out in collaboration with "Sapienza" Rome…”
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Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors
Published in ACS medicinal chemistry letters (09-02-2023)“…Protein tyrosine phosphatase SHP2 is an oncogenic protein that can regulate different cytokine receptor and receptor tyrosine kinase signaling pathways. We…”
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Improved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and Benzamides
Published in ACS medicinal chemistry letters (11-04-2019)“…The application of class I HDAC inhibitors as cancer therapies is well established, but more recently their development for nononcological indications has…”
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Fishers’ perceptions of the European Union discards ban: perspective from south European fisheries
Published in Marine policy (01-02-2018)“…The estimated impact of the EU Landing Obligation was investigated, which bans discards of regulated species, in South European fisheries through stakeholders’…”
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Synthesis, molecular modeling and biological evaluation of two new chicoric acid analogs
Published in Natural product research (16-02-2017)“…Two conformationally constrained compounds similar to chicoric acid but lacking the catechol and carboxyl groups were prepared. In these analogues, the single…”
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