Search Results - "Rosser, Gabriel"

Novel evaluation metrics for sparse spatio-temporal point process hotspot predictions - a crime case study by Adepeju, Monsuru, Rosser, Gabriel, Cheng, Tao

“…Many physical and sociological processes are represented as discrete events in time and space. These spatio-temporal point processes are often sparse, meaning…”
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Predictive Crime Mapping: Arbitrary Grids or Street Networks? by Rosser, Gabriel, Davies, Toby, Bowers, Kate J., Johnson, Shane D., Cheng, Tao

“…Objectives Decades of empirical research demonstrate that crime is concentrated at a range of spatial scales, including street segments. Further, the degree of…”
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Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation by Badodi, Sara, Pomella, Nicola, Zhang, Xinyu, Rosser, Gabriel, Whittingham, John, Niklison-Chirou, Maria Victoria, Lim, Yau Mun, Brandner, Sebastian, Morrison, Gillian, Pollard, Steven M., Bennett, Christopher D., Clifford, Steven C., Peet, Andrew, Basson, M. Albert, Marino, Silvia

“…Deregulation of chromatin modifiers plays an essential role in the pathogenesis of medulloblastoma, the most common paediatric malignant brain tumour. Here, we…”
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Lineage specification in glioblastoma is regulated by METTL7B by Constantinou, Myrianni, Nicholson, James, Zhang, Xinyu, Maniati, Eleni, Lucchini, Sara, Rosser, Gabriel, Vinel, Claire, Wang, Jun, Lim, Yau Mun, Brandner, Sebastian, Nelander, Sven, Badodi, Sara, Marino, Silvia

“…Glioblastomas are the most common malignant brain tumors in adults; they are highly aggressive and heterogeneous and show a high degree of plasticity. Here, we…”
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Signal-dependent turnover of the bacterial flagellar switch protein FliM by Delalez, Nicolas J., Wadhams, George H., Rosser, Gabriel, Xue, Quan, Brown, Mostyn T., Dobbie, Ian M., Berry, Richard M., Leake, Mark C., Armitage, Judith P., Berg, Howard C.

“…Most biological processes are performed by multiprotein complexes. Traditionally described as static entities, evidence is now emerging that their components…”
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Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma by Vinel, Claire, Rosser, Gabriel, Guglielmi, Loredana, Constantinou, Myrianni, Pomella, Nicola, Zhang, Xinyu, Boot, James R., Jones, Tania A., Millner, Thomas O., Dumas, Anaelle A., Rakyan, Vardhman, Rees, Jeremy, Thompson, Jamie L., Vuononvirta, Juho, Nadkarni, Suchita, El Assan, Tedani, Aley, Natasha, Lin, Yung-Yao, Liu, Pentao, Nelander, Sven, Sheer, Denise, Merry, Catherine L. R., Marelli-Berg, Federica, Brandner, Sebastian, Marino, Silvia

“…Epigenetic mechanisms which play an essential role in normal developmental processes, such as self-renewal and fate specification of neural stem cells (NSC)…”
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Global hypo-methylation in a proportion of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape by Boot, James, Rosser, Gabriel, Kancheva, Dailya, Vinel, Claire, Lim, Yau Mun, Pomella, Nicola, Zhang, Xinyu, Guglielmi, Loredana, Sheer, Denise, Barnes, Michael, Brandner, Sebastian, Nelander, Sven, Movahedi, Kiavash, Marino, Silvia

“…We describe a subset of glioblastoma, the most prevalent malignant adult brain tumour, harbouring a bias towards hypomethylation at defined differentially…”
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Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma by Badodi, Sara, Dubuc, Adrian, Zhang, Xinyu, Rosser, Gabriel, Da Cunha Jaeger, Mariane, Kameda-Smith, Michelle M., Morrissy, Anca Sorana, Guilhamon, Paul, Suetterlin, Philipp, Li, Xiao-Nan, Guglielmi, Loredana, Merve, Ashirwad, Farooq, Hamza, Lupien, Mathieu, Singh, Sheila K., Basson, M. Albert, Taylor, Michael D., Marino, Silvia

“…We describe molecular convergence between BMI1 and CHD7 in the initiation of medulloblastoma. Identified in a functional genomic screen in mouse models, a…”
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c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism by Merve, Ashirwad, Zhang, Xinyu, Pomella, Nicola, Acquati, Serena, Hoeck, Joerg D, Dumas, Anaelle, Rosser, Gabriel, Li, Yichen, Jeyapalan, Jennie, Vicenzi, Silvia, Fan, Qianhai, Yang, Zeng Jie, Sabò, Arianna, Sheer, Denise, Behrens, Axel, Marino, Silvia

“…Choroid plexus tumours (CPTs) account for 2-5% of brain tumours in children. They can spread along the neuraxis and can recur after treatment. Little is known…”
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Novel methods for analysing bacterial tracks reveal persistence in Rhodobacter sphaeroides by Rosser, Gabriel, Fletcher, Alexander G, Wilkinson, David A, de Beyer, Jennifer A, Yates, Christian A, Armitage, Judith P, Maini, Philip K, Baker, Ruth E

“…Tracking bacteria using video microscopy is a powerful experimental approach to probe their motile behaviour. The trajectories obtained contain much…”
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Correction to: c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism by Merve, Ashirwad, Zhang, Xinyu, Pomella, Nicola, Acquati, Serena, Hoeck, Joerg D, Dumas, Anaelle, Rosser, Gabriel, Li, Yichen, Jeyapalan, Jennie, Vicenzi, Silvia, Fan, Qianhai, Yang, Zeng Jie, Sabò, Arianna, Sheer, Denise, Behrens, Axel, Marino, Silvia

“…In the original version of this article [1], there was 1 error in the affiliation of the European Institute of Oncology (affiliation 3). In this correction…”
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Improving the Robustness and Accuracy of Crime Prediction with the Self-Exciting Point Process Through Isotropic Triggering by Rosser, Gabriel, Cheng, Tao

“…The self-exciting point process (SEPP) is a model of the spread of crime in space and time, incorporating background and triggering processes. It shows…”
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Microglia promote glioblastoma via mTOR‐mediated immunosuppression of the tumour microenvironment by Dumas, Anaelle A, Pomella, Nicola, Rosser, Gabriel, Guglielmi, Loredana, Vinel, Claire, Millner, Thomas O, Rees, Jeremy, Aley, Natasha, Sheer, Denise, Wei, Jun, Marisetty, Anantha, Heimberger, Amy B, Bowman, Robert L, Brandner, Sebastian, Joyce, Johanna A, Marino, Silvia

“…Tumour‐associated microglia/macrophages (TAM) are the most numerous non‐neoplastic populations in the tumour microenvironment in glioblastoma multiforme (GBM),…”
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EZH2 functional dichotomy in reactive oxygen species-stratified glioblastoma by Koh, Lynnette Wei Hsien, Pang, Qing You, Novera, Wisna, Lim, See Wee, Chong, Yuk Kien, Liu, Jinyue, Ang, Samantha Ya Lyn, Loh, Ron Weng Yee, Shao, Huilin, Ching, Jianhong, Wang, Yulan, Yip, Stephen, Tan, Patrick, Li, Shang, Low, David Chyi Yeu, Phelan, Anne, Rosser, Gabriel, Tan, Nguan Soon, Tang, Carol, Ang, Beng Ti

“…EZH2, well-known for its canonical methyltransferase activity in transcriptional repression in many cancers including glioblastoma (GBM), has an understudied…”
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In clinical practice, cerebral MRI in newborns is highly predictive of neurodevelopmental outcome after therapeutic hypothermia by Tharmapoopathy, Pavithira, Chisholm, Philippa, Barlas, Akif, Varsami, Marianna, Gupta, Neelam, Ekitzidou, Georgia, Ponnusamy, Vennila, Kappelou, Olga, Evanson, Jane, Rosser, Gabriel, Shah, Divyen K.

“…In the trials, a substantial proportion of newborns who underwent therapeutic hypothermia (TH) had an adverse outcome after hypoxic-ischaemic encephalopathy…”
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Choroid plexus papillomas are induced by c-Myc overexpression in the choroid plexus via a T-cell inflammatory mechanism by Merve, Ashirwad, Zhang, Xinyu, Pomella, Nicola, Acquati, Serena, Hoeck, Joerg, Dumas, Anaelle, Rosser, Gabriel, Li, Yichen, Jeyapalan, Jennie, Vicenzi, Silvia, Sabò, Arianna, Sheer, Denise, Behrens, Axel, Marino, Silvia

“…Abstract Choroid plexus tumours (CPT) account for up to 20% of brain tumours in children under 2 years of age. Histologically CPTs are classified into three…”
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Modelling and analysis of bacterial tracks suggest an active reorientation mechanism in Rhodobacter sphaeroides by Rosser, Gabriel, Baker, Ruth E., Armitage, Judith P., Fletcher, Alexander G.

“…Most free-swimming bacteria move in approximately straight lines, interspersed with random reorientation phases. A key open question concerns varying…”
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Discrete and Continuous Three Dimensional Simulations for Fluorescence Recovery In Bacteria by Rosser, Gabriel, Leake, Mark C.

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Straightforward multi-object video tracking for quantification of mosquito flight activity by Wilkinson, David A., Lebon, Cyrille, Wood, Trevor, Rosser, Gabriel, Gouagna, Louis Clément

“…[Display omitted] •The limitations of 2D video tracking for measuring insect activity were quantified.•Optimal protocols for filming and tracking mosquitoes…”
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From Birds to Bacteria: Generalised Velocity Jump Processes with Resting States by Taylor-King, Jake P., van Loon, E. Emiel, Rosser, Gabriel, Chapman, S. Jon

“…There are various cases of animal movement where behaviour broadly switches between two modes of operation, corresponding to a long-distance movement state and…”
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