Search Results - "Rossdam, Charlotte"

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells by Huggins, Ian J., Bos, Tomas, Gaylord, Olivia, Jessen, Christina, Lonquich, Brianna, Puranen, Angeline, Richter, Jenna, Rossdam, Charlotte, Brafman, David, Gaasterland, Terry, Willert, Karl

“…The WNT/β-catenin signaling pathway is a prominent player in many developmental processes, including gastrulation, anterior–posterior axis specification, organ…”
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Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo by Janosz, Ewa, Hetzel, Miriam, Spielmann, Hanna, Tumpara, Srinu, Rossdam, Charlotte, Schwabbauer, Marc, Kloos, Doreen, von Kaisenberg, Constantin, Schambach, Axel, Buettner, Falk F. R., Janciauskiene, Sabina, Lachmann, Nico, Moritz, Thomas

“…Inherited deficiency of the antiprotease alpha-1 antitrypsin (AAT) is associated with liver failure and early-onset emphysema. In mice, in vivo lentiviral…”
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The monosialoganglioside GM1a protects against complement attack by Wedekind, Henri, Beimdiek, Julia, Rossdam, Charlotte, Kats, Elina, Wittek, Vanessa, Schumann, Lisa, Sörensen-Zender, Inga, Fenske, Arno, Weinhold, Birgit, Schmitt, Roland, Tiede, Andreas, Büttner, Falk F. R., Münster-Kühnel, Anja, Abeln, Markus

“…The complement system is a part of the innate immune system in the fluid phase and efficiently eliminates pathogens. However, its activation requires tight…”
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Differential expression patterns of glycosphingolipids and C‐type lectin receptors on immune cells in absence of functional regulatory T cells by Jirmo, Adan C., Rossdam, Charlotte, Grychtol, Ruth, Happle, Christine, Gerardy‐Schahn, Rita, Buettner, Falk F. R., Hansen, Gesine

“…Background Glycosylation is a common and complex type of protein posttranslational modification. Altered glycosylation of immunoglobulins in autoimmune…”
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Cell‐autonomous impact of polysialic acid‐producing enzyme ST8SIA2 on developmental migration and distribution of cortical interneurons by Schuster, Ute E., Rossdam, Charlotte, Röckle, Iris, Schiff, Miriam, Hildebrandt, Herbert

“…In humans, variations in the polysialic acid‐producing enzyme ST8SIA2 and disturbances in the cortical inhibitory system are associated with neurodevelopmental…”
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Targeting the glycan epitope type I N-acetyllactosamine enables immunodepletion of human pluripotent stem cells from early differentiated cells by Rossdam, Charlotte, Brand, Smilla, Beimdiek, Julia, Oberbeck, Astrid, Albers, Marco Darius, Naujok, Ortwin, Buettner, Falk F R

“…Abstract Cell surface biomarkers are fundamental for specific characterization of human pluripotent stem cells (hPSCs). Importantly, they can be applied for…”
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412.7: Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo-glycans by Morticelli, Lucrezia, Rossdam, Charlotte, Cajic, Samanta, Böthig, Dietmar, Magdei, Mikhail, R Tuladhar, Sugat, Petersen, Björn, Fischer, Konrad, Rapp, Erdmann, Korossis, Sotirios, Haverich, Axel, Schnieke, Angelika, Niemann, Heiner, Buettner, Falk, Hilfiker, Andres

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Approach for Profiling of Glycosphingolipid Glycosylation by Multiplexed Capillary Gel Electrophoresis Coupled to Laser-Induced Fluorescence Detection To Identify Cell-Surface Markers of Human Pluripotent Stem Cells and Derived Cardiomyocytes by Rossdam, Charlotte, Konze, Sarah A, Oberbeck, Astrid, Rapp, Erdmann, Gerardy-Schahn, Rita, von Itzstein, Mark, Buettner, Falk F. R

“…Application of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as tissue transplants in regenerative medicine depends on cell-surface…”
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Reduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice by Klaus, Christine, Hansen, Jan N., Ginolhac, Aurélien, Gérard, Deborah, Gnanapragassam, Vinayaga S., Horstkorte, Rüdiger, Rossdam, Charlotte, Buettner, Falk F.R., Sauter, Thomas, Sinkkonen, Lasse, Neumann, Harald, Linnartz-Gerlach, Bettina

“…Sialic acid-binding Ig-like lectin (Siglec) receptors are linked to neurodegenerative processes, but the role of sialic acids in physiological aging is still…”
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Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions by Starzonek, Sarah, Maar, Hanna, Labitzky, Vera, Wicklein, Daniel, Rossdam, Charlotte, Buettner, Falk F R, Wolters-Eisfeld, Gerrit, Guengoer, Cenap, Wagener, Christoph, Schumacher, Udo, Lange, Tobias

“…Endothelial E- and P-selectins promote metastasis formation by interacting with sialyl-Lewis X and A (sLeX/sLeA) on circulating tumor cells. This interaction…”
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Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways by Cumin, Cécile, Huang, Yen-Lin, Rossdam, Charlotte, Ruoff, Felix, Céspedes, Susana Posada, Liang, Ching-Yeu, Lombardo, Flavio C., Coelho, Ricardo, Rimmer, Natalie, Konantz, Martina, López, Mónica Núñez, Alam, Shahidul, Schmidt, Alexander, Calabrese, Diego, Fedier, Andre, Vlajnic, Tatjana, von Itzstein, Mark, Templin, Markus, Buettner, Falk F.R., Everest-Dass, Arun, Heinzelmann-Schwarz, Viola, Jacob, Francis

“…The molecular repertoire promoting cancer cell plasticity is not fully elucidated. Here, we propose that glycosphingolipids (GSLs), specifically the globo and…”
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Genetic knockout of porcine GGTA1 or CMAH/GGTA1 is associated with the emergence of neo‐glycans by Morticelli, Lucrezia, Rossdam, Charlotte, Cajic, Samanta, Böthig, Dietmar, Magdei, Mikhail, Tuladhar, Sugat Ratna, Petersen, Björn, Fischer, Konrad, Rapp, Erdmann, Korossis, Sotirios, Haverich, Axel, Schnieke, Angelika, Niemann, Heiner, Buettner, Falk F. R., Hilfiker, Andres

“…Background Pig‐derived tissues could overcome the shortage of human donor organs in transplantation. However, the glycans with terminal α‐Gal and Neu5Gc, which…”
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