Search Results - "Rossato, Mateus Fortes"
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TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress
Published in Brain (London, England : 1878) (01-05-2016)“…Despite intense investigation, the mechanisms of the different forms of trigeminal neuropathic pain remain substantially unidentified. The transient receptor…”
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2
Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats
Published in Pain (Amsterdam) (01-08-2011)“…Gout is characterized by the deposition of monosodium urate (MSU) crystals. Despite being one of the most painful forms of arthritis, gout and the mechanisms…”
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3
Antiplatelet, Antithrombotic, and Fibrinolytic Activities of Campomanesia xanthocarpa
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…In a previous work based on popular belief, Campomanesia xanthocarpa Berg., popularly known as “guavirova”, showed to have a potential effect in the control of…”
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4
TRPA1 receptor stimulation by hydrogen peroxide is critical to trigger hyperalgesia and inflammation in a model of acute gout
Published in Free radical biology & medicine (01-07-2014)“…Acute gout attacks produce severe joint pain and inflammation associated with monosodium urate (MSU) crystals leading to oxidative stress production. The…”
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Transient receptor potential ankyrin 1 (TRPA1) plays a critical role in a mouse model of cancer pain
Published in International journal of cancer (15-01-2019)“…There is a major, unmet need for the treatment of cancer pain, and new targets and medicines are required. The transient receptor potential ankyrin 1 (TRPA1),…”
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What do we know about Toll-Like Receptors Involvement in Gout Arthritis?
Published in Endocrine, metabolic & immune disorders drug targets (01-01-2023)“…Toll-like receptors (TLRs) are a well-characterized family of cell-bound pattern recognition receptors able to identify and respond to conserved structures of…”
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Management of Neuropathic Chronic Pain with Methadone Combined with Ketamine: A Randomized, Double Blind, Active-Controlled Clinical Trial
Published in Pain physician (01-03-2017)“…Methadone and ketamine are used in neuropathic pain management. However, the benefits of both drugs association are uncertain in the treatment of neuropathic…”
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Participation of transient receptor potential vanilloid 1 in paclitaxel-induced acute visceral and peripheral nociception in rodents
Published in European journal of pharmacology (05-06-2018)“…The clinical use of paclitaxel as a chemotherapeutic agent is limited by the severe acute and chronic hypersensitivity caused when it is administered via…”
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9
Eriodictyol: A flavonoid antagonist of the TRPV1 receptor with antioxidant activity
Published in Biochemical pharmacology (15-02-2011)“…Eriodictyol acts as an antagonist of the TRPV1 receptor and as an antioxidant; it induces antinociception without some of the side effects and limitations such…”
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10
The involvement of the TRPA1 receptor in a mouse model of sympathetically maintained neuropathic pain
Published in European journal of pharmacology (15-01-2015)“…Sympathetic fibres maintain some forms of neuropathic pain, but the underlying mechanisms are poorly understood. Therefore, this study investigated the…”
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Potentiation of Paclitaxel-Induced Pain Syndrome in Mice by Angiotensin I Converting Enzyme Inhibition and Involvement of Kinins
Published in Molecular neurobiology (01-12-2017)“…Paclitaxel is a chemotherapeutic agent used to treat solid tumours. However, it causes an acute and neuropathic pain syndrome that limits its use. Among the…”
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12
Analgesic and side effects of intravenous recombinant Phα1β
Published in The journal of venomous animals and toxins including tropical diseases (17-04-2020)“…Intrathecal injection of voltage-sensitive calcium channel blocker peptide toxins exerts analgesic effect in several animal models of pain. Upon intrathecal…”
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13
Effects of Campomanesia xanthocarpa on biochemical, hematological and oxidative stress parameters in hypercholesterolemic patients
Published in Journal of ethnopharmacology (03-02-2010)“…Campomanesia xanthocarpa exert its lipid-lowering effects in hypercholesterolemic patients by a combination of its anti-oxidant and anti-HMGR activities. In…”
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14
Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer
Published in PLoS neglected tropical diseases (01-04-2013)“…The frequency of accidental spider bites in Brazil is growing, and poisoning due to bites from the spider genus Phoneutria nigriventer is the second most…”
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15
Contribution of peripheral vanilloid receptor to the nociception induced by injection of spermine in mice
Published in Pharmacology, biochemistry and behavior (01-10-2011)“…Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or…”
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Anti-nociceptive effect of stigmasterol in mouse models of acute and chronic pain
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-11-2017)“…Stigmasterol is a common sterol found in plants, but the anti-nociceptive effect of this compound and its mechanism of action are not fully explored. Thus, in…”
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Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties
Published in The Journal of pharmacology and experimental therapeutics (01-11-2012)“…The transient receptor potential vanilloid 1 (TRPV1) receptor is relevant to the perception of noxious information and has been studied as a therapeutic target…”
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Antinociceptive and antidepressant-like effects of the crude extract of Vitex megapotamica in rats
Published in Journal of ethnopharmacology (04-11-2016)“…Vitex megapotamica (Spreng) Moldenke has been used in South American folk medicine to treat inflammatory diseases. However, the effects of V. megapotamica on…”
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Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats
Published in Journal of photochemistry and photobiology. B, Biology (05-04-2014)“…Ultraviolet B (UVB) irradiation mainly affects biological tissues by inducing an increase in reactive oxygen species (ROS) production which leads to…”
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Anti-inflammatory Effects of Vitamin E on Adjuvant-Induced Arthritis in Rats
Published in Inflammation (01-04-2015)“…Vitamin E (vit-E) is a lipophilic antioxidant, and its anti-inflammatory activity is still not full characterized. Thus, our goal was to investigate the…”
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