Search Results - "Rossato, Marzia"

Negative regulation of Toll-like receptor 4 signaling by IL-10–dependent microRNA-146b by Curtale, Graziella, Mirolo, Massimiliano, Renzi, Tiziana Ada, Rossato, Marzia, Bazzoni, Flavia, Locati, Massimo

“…Toll-like receptors (TLRs) play key roles in detecting pathogens and initiating inflammatory responses that, subsequently, prime specific adaptive responses…”
Get full text

On site DNA barcoding by nanopore sequencing by Menegon, Michele, Cantaloni, Chiara, Rodriguez-Prieto, Ana, Centomo, Cesare, Abdelfattah, Ahmed, Rossato, Marzia, Bernardi, Massimo, Xumerle, Luciano, Loader, Simon, Delledonne, Massimo

“…Biodiversity research is becoming increasingly dependent on genomics, which allows the unprecedented digitization and understanding of the planet's biological…”
Get full text

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals by Bazzoni, Flavia, Rossato, Marzia, Fabbri, Marco, Gaudiosi, Daniele, Mirolo, Massimiliano, Mori, Laura, Tamassia, Nicola, Mantovani, Alberto, Cassatella, Marco A, Locati, Massimo

“…Inflammation involves a coordinated, sequential, and self limiting sequence of events controlled by positive and negative regulatory mechanisms. Recent studies…”
Get full text

IL-10—induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes by Rossato, Marzia, Curtale, Graziella, Tamassia, Nicola, Castellucci, Monica, Mori, Laura, Gasperini, Sara, Mariotti, Barbara, De Luca, Mariacristina, Mirolo, Massimiliano, Cassatella, Marco A., Locati, Massimo, Bazzoni, Flavia

“…IL-10 is a potent anti-inflammatory molecule that, in phagocytes, negatively targets cytokine expression at transcriptional and posttranscriptional levels…”
Get full text

Characterization of full-length CNBP expanded alleles in myotonic dystrophy type 2 patients by Cas9-mediated enrichment and nanopore sequencing by Alfano, Massimiliano, De Antoni, Luca, Centofanti, Federica, Visconti, Virginia Veronica, Maestri, Simone, Degli Esposti, Chiara, Massa, Roberto, D'Apice, Maria Rosaria, Novelli, Giuseppe, Delledonne, Massimo, Botta, Annalisa, Rossato, Marzia

“…Myotonic dystrophy type 2 (DM2) is caused by CCTG repeat expansions in the CNBP gene, comprising 75 to >11,000 units and featuring extensive mosaicism, making…”
Get full text

The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic Sclerosis by Mariotti, Barbara, Servaas, Nila Hendrika, Rossato, Marzia, Tamassia, Nicola, Cassatella, Marco A, Cossu, Marta, Beretta, Lorenzo, van der Kroef, Maarten, Radstake, Timothy R D J, Bazzoni, Flavia

“…TLR4 activation initiates a signaling cascade leading to the production of type I IFNs and of the downstream IFN-stimulated genes (ISGs). Recently, a number of…”
Get full text

AGO2-RIP-Seq reveals miR-34/miR-449 cluster targetome in sinonasal cancers by Tomasetti, Marco, Monaco, Federica, Rubini, Corrado, Rossato, Marzia, De Quattro, Concetta, Beltrami, Cristina, Sollini, Giacomo, Pasquini, Ernesto, Amati, Monica, Goteri, Gaia, Santarelli, Lory, Re, Massimo

“…Sinonasal tumours are heterogeneous malignancies, presenting different histological features and clinical behaviour. Many studies emphasize the role of…”
Get full text

A Long-Read Sequencing Approach for Direct Haplotype Phasing in Clinical Settings by Maestri, Simone, Maturo, Maria Giovanna, Cosentino, Emanuela, Marcolungo, Luca, Iadarola, Barbara, Fortunati, Elisabetta, Rossato, Marzia, Delledonne, Massimo

“…The reconstruction of individual haplotypes can facilitate the interpretation of disease risks; however, high costs and technical challenges still hinder their…”
Get full text

Understanding the molecular mechanisms of the multifaceted IL-10-mediated anti-inflammatory response: Lessons from neutrophils by Bazzoni, Flavia, Tamassia, Nicola, Rossato, Marzia, Cassatella, Marco A

“…Analysis of the molecular mechanisms governing the ability of IL-10 to keep inflammation under control has highlighted the existence of a great degree of…”
Get full text

Identification of a miR-146b -Fas ligand axis in the development of neutropenia in T large granular lymphocyte leukemia by Mariotti, Barbara, Calabretto, Giulia, Rossato, Marzia, Teramo, Antonella, Castellucci, Monica, Barilà, Gregorio, Leoncin, Matteo, Vicenzetto, Cristina, Facco, Monica, Semenzato, Gianpietro, Bazzoni, Flavia, Zambello, Renato

“…Tlarge granular lymphocyte leukemia (T-LGLL) is characterized by the expansion of several large granular lymphocyte clones, among which a subset of large…”
Get full text

Galectin-9 is an easy to measure biomarker for the interferon signature in systemic lupus erythematosus and antiphospholipid syndrome by van den Hoogen, Lucas L, van Roon, Joël A G, Mertens, Jorre S, Wienke, Judith, Lopes, Ana Pinheiro, de Jager, Wilco, Rossato, Marzia, Pandit, Aridaman, Wichers, Catharina G K, van Wijk, Femke, Fritsch-Stork, Ruth D E, Radstake, Timothy R D J

“…The interferon (IFN) signature is related to disease activity and vascular disease in systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS)…”
Get more information

Whole-exome sequencing of the mummified remains of Cangrande della Scala (1291–1329 CE) indicates the first known case of late-onset Pompe disease by Iadarola, Barbara, Lavezzari, Denise, Modi, Alessandra, Degli Esposti, Chiara, Beltrami, Cristina, Rossato, Marzia, Zaro, Valentina, Napione, Ettore, Latella, Leonardo, Lari, Martina, Caramelli, David, Salviati, Alessandro, Delledonne, Massimo

“…Mummified remains of relevant historical figures are nowadays an important source of information to retrace data concerning their private life and health,…”
Get full text

'Nebbiolo' genome assembly allows surveying the occurrence and functional implications of genomic structural variations in grapevines (Vitis vinifera L.) by Maestri, Simone, Gambino, Giorgio, Lopatriello, Giulia, Minio, Andrea, Perrone, Irene, Cosentino, Emanuela, Giovannone, Barbara, Marcolungo, Luca, Alfano, Massimiliano, Rombauts, Stephane, Cantu, Dario, Rossato, Marzia, Delledonne, Massimo, Calderón, Luciano

“…'Nebbiolo' is a grapevine cultivar typical of north-western Italy, appreciated for producing high-quality red wines. Grapevine cultivars are characterized by…”
Get full text

A Rapid and Accurate MinION-Based Workflow for Tracking Species Biodiversity in the Field by Maestri, Simone, Cosentino, Emanuela, Paterno, Marta, Freitag, Hendrik, Garces, Jhoana M, Marcolungo, Luca, Alfano, Massimiliano, Njunjić, Iva, Schilthuizen, Menno, Slik, Ferry, Menegon, Michele, Rossato, Marzia, Delledonne, Massimo

“…Genetic markers (DNA barcodes) are often used to support and confirm species identification. Barcode sequences can be generated in the field using portable…”
Get full text

Earliest Phase of Systemic Sclerosis Typified by Increased Levels of Inflammatory Proteins in the Serum by Cossu, Marta, Bon, Lenny, Preti, Carlo, Rossato, Marzia, Beretta, Lorenzo, Radstake, Timothy R. D. J.

“…Objective Patients with definite systemic sclerosis (SSc) who lack fibrotic features can be stratified into an intermediate stage of disease severity between…”
Get full text

The role of genetics and epigenetics in the pathogenesis of systemic sclerosis by Broen, Jasper C. A., Radstake, Timothy R. D. J., Rossato, Marzia

“…Key Points Systemic sclerosis (SSc) is a complex autoimmune disease, the pathogenesis of which is influenced by genetic, epigenetic and environmental factors…”
Get full text

Author Correction: Adaptive gene loss in the common bean pan-genome during range expansion and domestication by Cortinovis, Gaia, Vincenzi, Leonardo, Anderson, Robyn, Marturano, Giovanni, Marsh, Jacob Ian, Bayer, Philipp Emanuel, Rocchetti, Lorenzo, Frascarelli, Giulia, Lanzavecchia, Giovanna, Pieri, Alice, Benazzo, Andrea, Bellucci, Elisa, Di Vittori, Valerio, Nanni, Laura, Ferreira Fernández, Juan José, Rossato, Marzia, Aguilar, Orlando Mario, Morrell, Peter Laurent, Rodriguez, Monica, Gioia, Tania, Neumann, Kerstin, Alvarez Diaz, Juan Camilo, Gratias, Ariane, Klopp, Christophe, Bitocchi, Elena, Geffroy, Valérie, Delledonne, Massimo, Edwards, David, Papa, Roberto

Get full text

Adaptive gene loss in the common bean pan-genome during range expansion and domestication by Cortinovis, Gaia, Vincenzi, Leonardo, Anderson, Robyn, Marturano, Giovanni, Marsh, Jacob Ian, Bayer, Philipp Emanuel, Rocchetti, Lorenzo, Frascarelli, Giulia, Lanzavecchia, Giovanna, Pieri, Alice, Benazzo, Andrea, Bellucci, Elisa, Di Vittori, Valerio, Nanni, Laura, Ferreira Fernández, Juan José, Rossato, Marzia, Aguilar, Orlando Mario, Morrell, Peter Laurent, Rodriguez, Monica, Gioia, Tania, Neumann, Kerstin, Alvarez Diaz, Juan Camilo, Gratias, Ariane, Klopp, Christophe, Bitocchi, Elena, Geffroy, Valérie, Delledonne, Massimo, Edwards, David, Papa, Roberto

“…The common bean ( Phaseolus vulgaris L.) is a crucial legume crop and an ideal evolutionary model to study adaptive diversity in wild and domesticated…”
Get full text

Impaired activation of plasmacytoid dendritic cells via toll-like receptor 7/9 and STING is mediated by melanoma-derived immunosuppressive cytokines and metabolic drift by Monti, Matilde, Ferrari, Giorgia, Grosso, Valentina, Missale, Francesco, Bugatti, Mattia, Cancila, Valeria, Zini, Stefania, Segala, Agnese, La Via, Luca, Consoli, Francesca, Orlandi, Matteo, Valerio, Alessandra, Tripodo, Claudio, Rossato, Marzia, Vermi, William

“…Plasmacytoid dendritic cells (pDCs) infiltrate a large set of human cancers. Interferon alpha (IFN-α) produced by pDCs induces growth arrest and apoptosis in…”
Get full text

CRISPR/Cas9-Mediated Enrichment Coupled to Nanopore Sequencing Provides a Valuable Tool for the Precise Reconstruction of Large Genomic Target Regions by Lopatriello, Giulia, Maestri, Simone, Alfano, Massimiliano, Papa, Roberto, Di Vittori, Valerio, De Antoni, Luca, Bellucci, Elisa, Pieri, Alice, Bitocchi, Elena, Delledonne, Massimo, Rossato, Marzia

“…Complete and accurate identification of genetic variants associated with specific phenotypes can be challenging when there is a high level of genomic…”
Get full text