Search Results - "Ross S Berkowitz"
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Update on the diagnosis and management of gestational trophoblastic disease
Published in International journal of gynecology and obstetrics (01-10-2018)“…Gestational trophoblastic disease (GTD) arises from abnormal placenta and is composed of a spectrum of premalignant to malignant disorders. Changes in…”
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Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy
Published in Cell (26-02-2015)“…There is a lack of effective predictive biomarkers to precisely assign optimal therapy to cancer patients. While most efforts are directed at inferring drug…”
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Diagnosis and management of gestational trophoblastic disease: 2021 update
Published in International journal of gynecology and obstetrics (01-10-2021)“…Gestational trophoblastic disease (GTD) arises from abnormal placenta and is composed of a spectrum of premalignant to malignant disorders. Changes in…”
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4
Gestational trophoblastic disease
Published in The Lancet (British edition) (28-08-2010)“…Summary Gestational trophoblastic disease encompasses a range of pregnancy-related disorders, consisting of the premalignant disorders of complete and partial…”
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Placental site trophoblastic tumors and epithelioid trophoblastic tumors: Biology, natural history, and treatment modalities
Published in Gynecologic oncology (01-01-2017)“…Abstract Placental site (PSTT) and epithelioid trophoblastic tumor (ETT) are rare types of gestational trophoblastic neoplasia (GTN) that arise from…”
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Prediction of DNA Repair Inhibitor Response in Short-Term Patient-Derived Ovarian Cancer Organoids
Published in Cancer discovery (01-11-2018)“…Based on genomic analysis, 50% of high-grade serous ovarian cancers (HGSC) are predicted to have DNA repair defects. Whether this substantial subset of HGSCs…”
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Current advances in the management of gestational trophoblastic disease
Published in Gynecologic oncology (01-01-2013)Get full text
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Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2012)“…Chemoresistance to platinum therapy is a major obstacle that needs to be overcome in the treatment of ovarian cancer patients. The high rates and patterns of…”
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Evidence for lineage continuity between early serous proliferations (ESPs) in the Fallopian tube and disseminated high‐grade serous carcinomas
Published in The Journal of pathology (01-11-2018)“…The distal Fallopian tube is a site of origin for many ‘ovarian’ high‐grade serous carcinomas (HGSCs) with intraepithelial carcinomas (STICs) that share…”
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Update on the diagnosis and management of gestational trophoblastic disease
Published in International journal of gynecology and obstetrics (01-10-2015)Get full text
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Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
Published in eLife (31-10-2017)“…Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC). Combining small RNA sequencing from 179 human serum samples with a neural…”
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Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma : Evidence for a causal relationship
Published in The American journal of surgical pathology (01-02-2007)“…Proposed origins of pelvic serous carcinoma include the ovary, fallopian tube, and peritoneum. Prophylactic salpingo-oophorectomies in BRCA+ women have…”
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Primary Fallopian Tube Malignancies in BRCA-Positive Women Undergoing Surgery for Ovarian Cancer Risk Reduction
Published in Journal of clinical oncology (01-09-2007)“…To review the frequency and location of malignancies detected after prophylactic salpingo-oophorectomy in women with BRCA mutations. Medical records and…”
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Endometriosis-associated ovarian cancer: a review of pathogenesis
Published in International journal of molecular sciences (06-03-2013)“…Endometriosis is classically defined as the presence of endometrial glands and stroma outside of the endometrial lining and uterine musculature. With an…”
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Current Management of Gestational Trophoblastic Neoplasia
Published in Hematology/oncology clinics of North America (01-02-2012)“…Gestational trophoblastic neoplasms are malignant lesions that arise from placental villous and extravillous trophoblast. Four clinicopathologic conditions…”
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Profiles of Genomic Instability in High-Grade Serous Ovarian Cancer Predict Treatment Outcome
Published in Clinical cancer research (15-10-2012)“…High-grade serous cancer (HGSC) is the most common cancer of the ovary and is characterized by chromosomal instability. Defects in homologous recombination…”
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Neutrophil/lymphocyte ratio and other blood cell component counts are not associated with the development of postmolar gestational trophoblastic neoplasia
Published in PloS one (01-12-2022)“…To relate preevacuation platelet count and leukogram findings, especially neutrophil/lymphocyte ratios (NLR) and platelet/lymphocyte ratios with the occurrence…”
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A Gene Signature Predictive for Outcome in Advanced Ovarian Cancer Identifies a Survival Factor: Microfibril-Associated Glycoprotein 2
Published in Cancer cell (08-12-2009)“…Advanced stage papillary serous tumors of the ovary are responsible for the majority of ovarian cancer deaths, yet the molecular determinants modulating…”
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Comparison of benign peritoneal fluid- and ovarian cancer ascites-derived extracellular vesicle RNA biomarkers
Published in Journal of ovarian research (02-03-2018)“…Extracellular vesicles (EVs) are considered as a new class of resources for potential biomarkers. We analyzed expression of specific mRNA and miRNA in EVs…”
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Robotic versus open radical hysterectomy: A comparative study at a single institution
Published in Gynecologic oncology (01-12-2008)“…Abstract Objective To compare the short-term surgical outcome of patients undergoing robotic radical hysterectomy (RRH) versus open radical hysterectomy (ORH)…”
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