Search Results - "Ross‐Kaschitza, Daniela"

Identification of potent and selective small molecule inhibitors of the cation channel TRPM4 by Ozhathil, Lijo Cherian, Delalande, Clémence, Bianchi, Beatrice, Nemeth, Gabor, Kappel, Sven, Thomet, Urs, Ross‐Kaschitza, Daniela, Simonin, Céline, Rubin, Matthias, Gertsch, Jürg, Lochner, Martin, Peinelt, Christine, Reymond, Jean‐Louis, Abriel, Hugues

“…Background and Purpose TRPM4 is a calcium‐activated non‐selective cation channel expressed in many tissues and implicated in several diseases, and has not yet…”
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TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells by Kappel, Sven, Stokłosa, Paulina, Hauert, Barbara, Ross‐Kaschitza, Daniela, Borgström, Anna, Baur, Roland, Galván, José A., Zlobec, Inti, Peinelt, Christine

“…Transient receptor potential melastatin‐4 channel (TRPM4) dysregulation contributes to heart conditions, immune diseases, and cervical and prostate cancer. Up…”
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eIF4E and Interactors from Unicellular Eukaryotes by Ross-Kaschitza, Daniela, Altmann, Michael

“…eIF4E, the mRNA cap-binding protein, is well known as a general initiation factor allowing for mRNA-ribosome interaction and cap-dependent translation in…”
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Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes by Ozhathil, Lijo Cherian, Rougier, Jean-Sébastien, Arullampalam, Prakash, Essers, Maria C., Ross-Kaschitza, Daniela, Abriel, Hugues

“…Transient receptor potential melastatin member 4 (TRPM4) encodes a Ca2+-activated, non-selective cation channel that is functionally expressed in several…”
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The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5 by Iamshanova, Oksana, Hämmerli, Anne-Flore, Ramaye, Elise, Seljmani, Arbresh, Ross-Kaschitza, Daniela, Schärz, Noëlia, Essers, Maria, Guichard, Sabrina, Rougier, Jean-Sébastien, Abriel, Hugues

“…14-3-3 proteins are ubiquitous proteins that play a role in cardiac physiology (e.g., metabolism, development, and cell cycle). Furthermore, 14-3-3 proteins…”
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Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation by Hu, Yaopeng, Kaschitza, Daniela Ross, Essers, Maria, Arullampalam, Prakash, Fujita, Takayuki, Abriel, Hugues, Inoue, Ryuji

“…TRPM4 is a Ca 2+ -activated nonselective cation channel involved in cardiovascular physiology and pathophysiology. Based on cellular experiments and numerical…”
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Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors by Arullampalam, Prakash, Preti, Barbara, Ross-Kaschitza, Daniela, Lochner, Martin, Rougier, Jean-Sébastien, Abriel, Hugues

“…Background: The Transient Receptor Potential Melastatin member 4 ( TRPM4 ) gene encodes a calcium-activated non-selective cation channel expressed in several…”
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CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells by Kappel, Sven, Melek, Korollus, Ross-Kaschitza, Daniela, Hauert, Barbara, Gerber, Christian E, Lochner, Martin, Peinelt, Christine

“…Upon activation at low pH, TMEM206 conducts Cl ions across plasma and vesicular membranes. In a (patho)physiological context, TMEM206 was reported to…”
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Properties of the ternary complex formed by yeast eIF4E, p20 and mRNA by Arndt, Nick, Ross-Kaschitza, Daniela, Kojukhov, Artyom, Komar, Anton A., Altmann, Michael

“…Yeast p20 is a small, acidic protein that binds eIF4E, the cap-binding protein. It has been proposed to affect mRNA translation and degradation, however p20′s…”
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Contribution of the α5 nAChR Subunit and α5SNP to Nicotine-Induced Proliferation and Migration of Human Cancer Cells by Papapostolou, Irida, Ross-Kaschitza, Daniela, Bochen, Florian, Peinelt, Christine, Maldifassi, Maria Constanza

“…Nicotine in tobacco is known to induce tumor-promoting effects and cause chemotherapy resistance through the activation of nicotinic acetylcholine receptors…”
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Functional Consequences of the SCN5A -p.Y1977N Mutation within the PY Ubiquitylation Motif: Discrepancy between HEK293 Cells and Transgenic Mice by Casini, Simona, Albesa, Maxime, Wang, Zizun, Portero, Vincent, Ross-Kaschitza, Daniela, Rougier, Jean-Sébastien, Marchal, Gerard A, Chung, Wendy K, Bezzina, Connie R, Abriel, Hugues, Remme, Carol Ann

“…Dysfunction of the cardiac sodium channel Nav1.5 (encoded by the gene) is associated with arrhythmias and sudden cardiac death. mutations associated with long…”
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p53 alters intracellular Ca2+ signaling through regulation of TRPM4 by Kappel, Sven, Ross-Kaschitza, Daniela, Hauert, Barbara, Rother, Karen, Peinelt, Christine

“…•p53 represses promotor activity of the TRPM4 ion channel.•p53 knockout cells show increased TRPM4 protein and currents thereby reducing store-operated calcium…”
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The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Na.sub.v1.5 by Iamshanova, Oksana, Hämmerli, Anne-Flore, Ramaye, Elise, Seljmani, Arbresh, Ross-Kaschitza, Daniela, Schärz, Noëlia, Essers, Maria, Guichard, Sabrina, Rougier, Jean-Sébastien, Abriel, Hugues

“…Background 14-3-3 proteins are ubiquitous proteins that play a role in cardiac physiology (e.g., metabolism, development, and cell cycle). Furthermore, 14-3-3…”
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Development of chemical tools based on GSK-7975A to study store-operated calcium entry in cells by Tscherrig, Dominic, Bhardwaj, Rajesh, Biner, Daniel, Dernič, Jan, Ross-Kaschitza, Daniela, Peinelt, Christine, Hediger, Matthias A, Lochner, Martin

“…Many physiological functions, such as cell differentiation, proliferation, muscle contraction, neurotransmission and fertilisation, are regulated by changes of…”
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p53 alters intracellular Ca 2+ signaling through regulation of TRPM4 by Kappel, Sven, Ross-Kaschitza, Daniela, Hauert, Barbara, Rother, Karen, Peinelt, Christine

“…Altered expression of transient receptor potential channel melastatin 4 (TRPM4) contributes to several diseases, including cardiac conduction disorders, immune…”
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Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5 by Wang, Zizun, Vermij, Sarah H., Sottas, Valentin, Shestak, Anna, Ross-Kaschitza, Daniela, Zaklyazminskaya, Elena V., Hudmon, Andy, Pitt, Geoffrey S., Rougier, Jean-Sébastien, Abriel, Hugues

“…The cardiac voltage-gated sodium channel Na v 1.5 conducts the rapid inward sodium current crucial for cardiomyocyte excitability. Loss-of-function mutations…”
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Deletion of Trpm4 Alters the Function of the Na v 1.5 Channel in Murine Cardiac Myocytes by Ozhathil, Lijo Cherian, Rougier, Jean-Sébastien, Arullampalam, Prakash, Essers, Maria C, Ross-Kaschitza, Daniela, Abriel, Hugues

“…Transient receptor potential melastatin member 4 (TRPM4) encodes a Ca -activated, non-selective cation channel that is functionally expressed in several…”
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Calmodulin binds to the N-terminal domain of the cardiac sodium channel Na v 1.5 by Wang, Zizun, Vermij, Sarah H, Sottas, Valentin, Shestak, Anna, Ross-Kaschitza, Daniela, Zaklyazminskaya, Elena V, Hudmon, Andy, Pitt, Geoffrey S, Rougier, Jean-Sébastien, Abriel, Hugues

“…The cardiac voltage-gated sodium channel Na 1.5 conducts the rapid inward sodium current crucial for cardiomyocyte excitability. Loss-of-function mutations in…”
Get full text