Search Results - "Ross, G F"

Surfactant protein A-deficient mice are susceptible to group B streptococcal infection by LeVine, AM, Bruno, MD, Huelsman, KM, Ross, GF, Whitsett, JA, Korfhagen, TR

“…To determine the role of surfactant protein A (SP-A) in host defense, the murine SP-A locus was targeted by homologous recombination to produce mice lacking…”
Get full text

Altered Surfactant Function and Structure in SP-A Gene Targeted Mice by Korfhagen, Thomas R., Bruno, Michael D., Ross, Gary F., Huelsman, Karen M., Ikegami, Machiko, Jobe, Alan H., Wert, Susan E., Stripp, Barry R., Morris, Randal E., Glasser, Stephan W., Bachurski, Cindy J., Iwamoto, Harriet S., Whitsett, Jeffrey A.

“…The surfactant protein A (SP-A) gene was disrupted by homologous recombination in embryonic stem cells that were used to generate homozygous SP-A-deficient…”
Get full text

Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor by ROSS, G. F, BRUNO, M. D, UYEDA, M, SUZUKI, K, NAGAO, K, WHITSETT, J. A, KORFHAGEN, T. R

“…Cellular nuclease activity is a potential barrier to the successful delivery of foreign genes to mammalian cells. We tested the hypothesis that transfection in…”
Get full text

Surfactant-associated protein inhibits phospholipid secretion from type II cells by Rice, W R, Ross, G F, Singleton, F M, Dingle, S, Whitsett, J A

“…Secretion of [3H]phosphatidylcholine ([3H]PC) from isolated rat pulmonary type II epithelial cells was inhibited by the surfactant-associated protein of Mr =…”
Get more information

Interleukin-4 enhances pulmonary clearance of Pseudomonas aeruginosa by JAIN-VORA, S, LEVINE, A. M, CHRONEOS, Z, ROSS, G. F, HULL, W. M, WHITSETT, J. A

“…To determine the effects of interleukin-4 (IL-4) on bacterial clearance from the mouse lung, transgenic mice expressing IL-4 in respiratory epithelial cells…”
Get full text

New insights into SRY regulation through identification of 5' conserved sequences by Ross, Diana G F, Bowles, Josephine, Koopman, Peter, Lehnert, Sigrid

“…SRY is the pivotal gene initiating male sex determination in most mammals, but how its expression is regulated is still not understood. In this study we…”
Get full text

Specificity of lung surfactant protein SP-A for both the carbohydrate and the lipid moieties of certain neutral glycolipids by Childs, R A, Wright, J R, Ross, G F, Yuen, C T, Lawson, A M, Chai, W, Drickamer, K, Feizi, T

“…Binding specificity of the major surfactant protein SP-A from human and dog lung has been investigated. Radiobinding experiments have shown that both proteins…”
Get full text

Increased Metalloproteinase Activity, Oxidant Production, and Emphysema in Surfactant Protein D Gene-Inactivated Mice by Wert, Susan E., Yoshida, Mitsuhiro, LeVine, Ann Marie, Ikegami, Machiko, Jones, Tracy, Ross, Gary F., Fisher, James H., Korfhagen, Thomas R., Whitsett, Jeffrey A.

“…Targeted ablation of the surfactant protein D (SP-D) gene caused chronic inflammation, emphysema, and fibrosis in the lungs of SP-D (-/-) mice. Although lung…”
Get full text

Altered Stability of Pulmonary Surfactant in SP-C-Deficient Mice by Glasser, Stephan W., Burhans, Michael S., Korfhagen, Thomas R., Na, Cheng-Lun, Sly, Peter D., Ross, Gary F., Ikegami, Machiko, Whitsett, Jeffrey A.

“…The surfactant protein C (SP-C) gene encodes an extremely hydrophobic, 4-kDa peptide produced by alveolar epithelial cells in the lung. To discern the role of…”
Get full text

Phospholipid binding and biophysical activity of pulmonary surfactant-associated protein (SAP)-35 and its non-collagenous COOH-terminal domains by Ross, G F, Notter, R H, Meuth, J, Whitsett, J A

“…Surfactant-associated protein of Mr = 35,000, SAP-35, is the major glycoprotein present in mammalian pulmonary surfactants. In this study, canine SAP-35 and…”
Get full text

Surfactant Protein-D Regulates Surfactant Phospholipid Homeostasis in Vivo by Korfhagen, Thomas R., Sheftelyevich, Vladimir, Burhans, Michael S., Bruno, Michael D., Ross, Gary F., Wert, Susan E., Stahlman, Mildred T., Jobe, Alan H., Ikegami, Machiko, Whitsett, Jeffrey A., Fisher, James H.

“…Surfactant protein D (SP-D) is a 43-kDa member of the collectin family of collagenous lectin domain-containing proteins that is expressed in epithelial cells…”
Get full text

Surfactant Protein-A Binds Group B Streptococcus Enhancing Phagocytosis and Clearance from Lungs of Surfactant Protein-A-Deficient Mice by LeVine, Ann Marie, Kurak, Kim E, Wright, Jo Rae, Watford, Wendy T, Bruno, Michael D, Ross, Gary F, Whitsett, Jeffrey A, Korfhagen, Thomas R

“…Surfactant protein-A (SP-A) gene-targeted mice clear group B streptococcus (GBS) from the lungs at a slower rate than wild-type mice. To determine mechanisms…”
Get full text

Intra-amniotic endotoxin increases pulmonary surfactant proteins and induces SP-B processing in fetal sheep by Bachurski, C J, Ross, G F, Ikegami, M, Kramer, B W, Jobe, A H

“…Intra-amniotic (IA) endotoxin induces lung maturation within 6 days in fetal sheep of 125 days gestational age. To determine the early fetal lung response to…”
Get more information

Lectin activity of the major surfactant protein (SP-A) may participate in, but is not required for, binding to rat type II cells by Thorkelsson, T, Ciraolo, GM, Ross, GF, Whitsett, JA, Morris, RE

“…Pulmonary surfactant is a complex mixture of lipids and proteins, of which surfactant protein A (SP-A) is the most abundant glycoprotein. The SP-A molecule has…”
Get full text

Assessment of ORAI1-mediated basal calcium influx in mammary epithelial cells by Ross, Diana G F, Smart, Chanel E, Azimi, Iman, Roberts-Thomson, Sarah J, Monteith, Gregory R

“…The entry of calcium ions into mammary gland epithelial cells is one of the least well-understood processes in the transport of calcium into milk during…”
Get full text

Measurement of the Intrinsic Properties of Materials by Time-Domain Techniques by Nicolson, A. M., Ross, G. F.

“…In this paper a method is presented for determining the complex permittivity and permeability of linear materials in the frequency domain by a single…”
Get full text

Intermolecular cross-links mediate aggregation of phospholipid vesicles by pulmonary surfactant protein SP-A by Ross, Gary F, Sawyer, Jeff, O'Connor, Terri, Whitsett, Jeffrey A

“…As the most abundant glycoprotein component of pulmonary surfactant, SP-A (Mr = 30,000-36,000) plays a central role in the organization of phospholipid…”
Get full text

Human surfactant protein-A contains blood group A antigenic determinants by STAHLMAN, M. T, GRAY, M. E, ROSS, G. F, HULL, W. M, WIKENHEISER, K, DINGLE, S, ZELENSKI-LOW, K. R, WHITSETT, J. A

“…A major blood group antigenic epitope was identified on human pulmonary surfactant protein A (SP-A). MAb and polyclonal antibodies generated against purified…”
Get full text

IL-4 increases surfactant and regulates metabolism in vivo by Ikegami, M, Whitsett, J A, Chroneos, Z C, Ross, G F, Reed, J A, Bachurski, C J, Jobe, A H

“…Mice that express interleukin (IL)-4 in Clara cells (CCSP-IL-4) develop chronic airway inflammation and an alveolar proteinosis-like syndrome. To identify the…”
Get more information

Career stress responses among hospitality employees by Ross, Glenn F.

“…Career patterns among hospitality employees have received relatively little attention from disciplines such as organizational psychology. This study seeks to…”
Get full text