Search Results - "Ross, Duncan B."
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Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice
Published in Blood (25-09-2014)“…Posttransplantation cyclophosphamide (PTCy) is an effective prophylaxis against graft-versus-host disease (GVHD). However, it is unknown whether PTCy works…”
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Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants
Published in Investigative ophthalmology & visual science (01-04-2015)“…The primary objective of the present study was to identify the kinetics and origin of ocular infiltrating T cells in a preclinical model of graft-versus-host…”
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The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success
Published in Immunologic research (01-12-2013)“…Since its inception in the mid-twentieth century, the complication limiting the application and utility of allogeneic hematopoietic stem cell transplantation…”
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Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 αII isoform (S6K1αII)
Published in Protein expression and purification (01-03-2008)“…S6K1αII is a member of the AGC subfamily of serine–threonine protein kinases, whereby catalytic activation requires dual phosphorylation of critical residues…”
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Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1)
Published in Protein expression and purification (01-02-2008)“…S6K1 is a member of the AGC subfamily of serine-threonine protein kinases, whereby catalytic activation requires dual phosphorylation of critical residues in…”
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Journal Article -
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Post-Transplant Cyclophosphamide (PTC) Gvhd Prophylaxis: Kinetics of Proliferation of Donor T Cells Affects Susceptibility to PTC Administration
Published in Blood (18-11-2011)“…Abstract 4029 PTC has been found to diminish experimental GVHD and is under investigation in clinical studies (Luznik Blood 2010). An important question is…”
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Post-Transplant Cyclophosphamide Treatment Ameliorates Experimental Gvhd While Permitting Lymphopenic Expansion of Non-Host Reactive Donor T Cells
Published in Blood (19-11-2010)“…Abstract 3751 Following myeloablative as well as reduced intensity conditioning regimens, recipients of allogeneic T cell replete (TCR) HLA matched sibling)or…”
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Donor T cell outcome and immune reconstitution following post-transplant cyclophosphamide and regulatory MHC cell therapy in recipients of mhc matched allogeneic hematopoietic stem cell transplants
Published 01-01-2012“…Blood cancers result in the deaths of over 50,000 patients worldwide annually. While capable of inducing temporary or occasionally complete remissions in…”
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Dissertation -
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Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII)
Published in Protein expression and purification (01-03-2008)“…S6K1alphaII is a member of the AGC subfamily of serine-threonine protein kinases, whereby catalytic activation requires dual phosphorylation of critical…”
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Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70kDa 40S ribosomal protein S6 kinase-1 (S6K1)
Published in Protein expression and purification (01-02-2008)“…S6K1 is a member of the AGC subfamily of serine–threonine protein kinases, whereby catalytic activation requires dual phosphorylation of critical residues in…”
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Journal Article -
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Laser and Microwave Observations of Sea-Surface Condition for Fetch-Limited 17- to 25-m/s Winds
Published in IEEE transactions on geoscience electronics (01-10-1970)“…The variability of sea-surface conditions has been observed from a low-flying aircraft by a laser-wave profiling system and a scanning horizontally polarized…”
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Journal Article